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Des Moines International Airport to Columbus flight
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Cheap Flights from Des Moines International Airport to Columbus

Search for flights from Des Moines International Airport to Columbus and check out affordable one-way and round-trip options.

  • One way
  • Round-trip
sortSort by: Lowest Price
  • Sort by: Lowest Price
  • Sort by: Earliest Flight
      • DSM18:41
        4h 18m
        1 stop
        CMH23:59
        Des Moines - Columbus|Wed, Jun 5|United Airlines
        $153$273
        44% OFF
        44% OFF
        $273$153
      • DSM18:41
        4h 18m
        1 stop
        CMH23:59
        Des Moines - Columbus|Mon, Jun 10|United Airlines
        $180$273
        34% OFF
        34% OFF
        $273$180
      • DSM09:19
        12h 23m
        1 stop
        CMH22:42
        Des Moines - Columbus|Wed, Jun 5|Frontier Airlines
        $182$273
        33% OFF
        33% OFF
        $273$182
      • DSM08:00
        4h 21m
        1 stop
        CMH13:21
        Des Moines - Columbus|Sat, Jun 29|United Airlines
        $205
        $205
      • DSM05:00
        8h 20m
        1 stop
        CMH14:20
        Des Moines - Columbus|Mon, Jun 10|American Airlines
        $216
        $216
      • DSM09:54
        13h 5m
        1 stop
        CMH23:59
        Des Moines - Columbus|Wed, Jun 5|American Airlines
        $221
        $221
      • DSM06:54
        4h 49m
        1 stop
        CMH12:43
        Des Moines - Columbus|Sat, Jun 29|American Airlines
        $237
        $237
      • DSM11:30
        4h 14m
        1 stop
        CMH16:44
        Des Moines - Columbus|Wed, Jun 12|United Airlines
        $242
        $242
      • DSM08:00
        4h 21m
        1 stop
        CMH13:21
        Des Moines - Columbus|Sun, Jun 30|United Airlines
        $244
        $244
      • DSM06:30
        5h 50m
        1 stop
        CMH13:20
        Des Moines - Columbus|Wed, Jun 5|Delta Air Lines
        $244
        $244
      • DSM13:00
        3h 5m
        Direct
        CMH14:00
        Des Moines - Columbus|Sun, Jun 9|United Airlines
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Selected Airlines from Des Moines International Airport to Columbus

See which airlines fly from Des Moines International Airport to Columbus. Find the airline that best meets your travel needs by comparing prices and treat yourself to an enjoyable journey.

United Airlines
From $153
Frontier Airlines
From $180
American Airlines
From $216
Delta Air Lines
From $244
Southwest Airlines
From $323
Allegiant Air
From $342
ANA airlines

Find more flights and airlines

There are 2 airport(s) in Columbus. Discover the top routes now!

Learn about different airports in Columbus, find the best flight and transfer options, and plan your journey.

  • 21.04 km from downtown Columbus
    Rickenbacker International Airport
    Tickets From
    $255
  • 0.25 km from downtown ColumbusCheapestClosest
    John Glenn Columbus International Airport
    Tickets From
    $153
Flight Schedule from Des Moines International Airport to Columbus

Check the schedule for flights from Des Moines International Airport to Columbus and find the flight that best matches your travel plans.

Flight info.
Departure
Arrival
Weekly Schedule

  1. AA3418

    American Airlines

    05:54

    DSM

    1.4h

    07:21

    ORD

    ---WTFS
    Search

  2. AA6097

    American Airlines

    08:05

    ORD

    1.5h

    10:35

    CMH

    --TWT-S

  3. DL488

    Delta Air Lines

    05:55

    DSM

    2.2h

    09:05

    ATL

    ----TFS
    Search

  4. DL1522

    Delta Air Lines

    08:55

    ATL

    1.6h

    10:28

    CMH

    ----TFS

  5. DL5414

    Delta Air Lines

    06:30

    DSM

    1.8h

    09:19

    DTW

    SMTWTFS
    Search

  6. DL4061

    Delta Air Lines

    12:26

    DTW

    1.0h

    13:27

    CMH

    ----T-S

  7. DL5414

    Delta Air Lines

    06:30

    DSM

    1.8h

    09:19

    DTW

    SMTWTFS
    Search

  8. DL5670

    Delta Air Lines

    12:20

    DTW

    1.0h

    13:20

    CMH

    SMTW---

  9. AA2488

    American Airlines

    07:08

    DSM

    2.4h

    10:30

    CLT

    SMTWTFS
    Search

  10. AA5663

    American Airlines

    11:09

    CLT

    1.6h

    12:44

    CMH

    --TWTFS

  11. UA2306

    United Airlines

    11:30

    DSM

    1.5h

    13:02

    ORD

    SMTWTF-
    Search

  12. UA503

    United Airlines

    14:20

    ORD

    1.4h

    16:44

    CMH

    SMTWT--

  13. DL5175

    Delta Air Lines

    16:10

    DSM

    1.8h

    18:57

    DTW

    -----F-
    Search

  14. DL5847

    Delta Air Lines

    21:45

    DTW

    1.0h

    22:44

    CMH

    ----TFS

  15. DL2086

    Delta Air Lines

    18:14

    DSM

    2.2h

    21:25

    ATL

    SMTWTFS
    Search

  16. DL1459

    Delta Air Lines

    22:26

    ATL

    1.5h

    23:56

    CMH

    ----TFS

  17. WN776

    Southwest Airlines

    18:40

    DSM

    1.1h

    19:45

    STL

    -MTWT--
    Search

  18. WN4601

    Southwest Airlines

    20:35

    STL

    1.3h

    22:55

    CMH

    -MTWT--

  19. UA5631

    United Airlines

    18:41

    DSM

    1.5h

    20:12

    ORD

    SMTWT--
    Search

  20. UA1492

    United Airlines

    21:35

    ORD

    1.4h

    23:59

    CMH

    SMTWTFS
Find more flights and airlines

Flight Info of Flights from Des Moines International Airport to Columbus

Cheapest nonstop flight price

$153

Off-season for travel

May

Peak season for travel

July

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