App
Help
USD
Search Bookings
Trip.com
>
Flights
>
Flights to Brussels
>
Chicago to Brussels flight
>
O'Hare International Airport to Brussels flight
Worldwide Coverage
Worldwide Coverage
Flights to over 5,000 cities
One-stop Service Guarantee
One-stop Service Guarantee
Price guaranteed upon confirmed payment, booking guaranteed once tickets issued
Secure Payment
Secure Payment
Convenient & reliable booking and payment system

Cheap Flights from O'Hare International Airport to Brussels

Search for flights from O'Hare International Airport to Brussels and check out affordable one-way and round-trip options.

  • One way
  • Round-trip
sortSort by: Lowest Price
  • Sort by: Lowest Price
  • Sort by: Earliest Flight
      • ORD22:35
        13h 25m
        1 stop
        BRU19:00
        Chicago - Brussels|Mon, Apr 29|American Airlines
        $344$580
        41% OFF
        41% OFF
        $580$344
      • ORD18:05
        17h 15m
        2 stops
        BRU18:20
        Chicago - Brussels|Wed, May 1|American Airlines
        $360$580
        38% OFF
        38% OFF
        $580$360
      • ORD08:20
        26h 20m
        2 stops
        BRU17:40
        Chicago - Brussels|Mon, May 6|American Airlines
        $367$580
        37% OFF
        37% OFF
        $580$367
      • ORD16:35
        22h 55m
        1 stop
        BRU22:30
        Chicago - Brussels|Tue, May 14|American Airlines
        $379
        $379
      • ORD07:00
        21h 30m
        2 stops
        BRU11:30
        Chicago - Brussels|Wed, Jul 17|American Airlines
        $383
        $383
      • ORD21:15
        31h 15m
        2 stops
        BRU11:30
        Chicago - Brussels|Thu, May 30|United Airlines
        $383
        $383
      • ORD08:15
        20h 15m
        2 stops
        BRU11:30
        Chicago - Brussels|Wed, Jun 5|American Airlines
        $386
        $386
      • ORD21:15
        31h 15m
        2 stops
        BRU11:30
        Chicago - Brussels|Tue, May 28|United Airlines
        $388
        $388
      • ORD23:05
        27h 15m
        2 stops
        BRU09:20
        Chicago - Brussels|Sun, May 5|American Airlines
        $390
        $390
      • ORD23:00
        28h 15m
        2 stops
        BRU10:15
        Chicago - Brussels|Tue, May 21|American Airlines
        $391
        $391
      • ORD13:00
        3h 5m
        Direct
        BRU14:00
        Chicago - Brussels|Sun, May 5|American Airlines
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Selected Airlines from O'Hare International Airport to Brussels

See which airlines fly from O'Hare International Airport to Brussels. Find the airline that best meets your travel needs by comparing prices and treat yourself to an enjoyable journey.

American Airlines
From $344
Spirit Airlines
From $369
United Airlines
From $382
Delta Air Lines
From $402
Icelandair
From $425
Turkish Airlines
From $458
Iberia
From $473
TAP Air Portugal
From $476
Scandinavian Airlines
From $487
Air Canada
From $494
ANA airlines
Find more flights and airlines

There are 2 airport(s) in Brussels. Discover the top routes now!

Learn about different airports in Brussels, find the best flight and transfer options, and plan your journey.

  • 0.62 km from downtown BrusselsCheapestClosest
    Brussels National Airport
    Tickets From
    $344
  • 49.65 km from downtown Brussels
    Brussels South Charleroi Airport
    Tickets From
    $473
Flight Schedule from O'Hare International Airport to Brussels

Check the schedule for flights from O'Hare International Airport to Brussels and find the flight that best matches your travel plans.

Flight info.
Departure
Arrival
Weekly Schedule

  1. UA8344

    United Airlines

    10:55

    ORD

    2.2h

    14:08

    YUL

    SMTWTFS
    Search

  2. UA8612

    United Airlines

    17:15

    YUL

    7.1h

    06:20

    BRU

    SMTWTFS

  3. UA2654

    United Airlines

    15:42

    ORD

    2.5h

    19:15

    EWR

    SMTWTFS
    Search

  4. UA999

    United Airlines

    18:40

    EWR

    7.1h

    07:45

    BRU

    SMTWTFS

  5. OS066

    Austrian Airlines

    16:20

    ORD

    9.0h

    08:20

    VIE

    SMTWTFS
    Search

  6. OS359

    Austrian Airlines

    12:20

    VIE

    1.8h

    14:05

    BRU

    SMT-TFS

  7. IB6274

    Iberia

    16:35

    ORD

    8.3h

    07:50

    MAD

    SMTWTFS
    Search

  8. IB3206

    Iberia

    09:05

    MAD

    2.3h

    11:25

    BRU

    SMTWTFS

  9. TP244

    TAP Air Portugal

    18:00

    ORD

    7.9h

    07:55

    LIS

    S-T-T-S
    Search

  10. TP642

    TAP Air Portugal

    11:20

    LIS

    2.8h

    15:05

    BRU

    SMTWTFS

  11. LX009

    Swiss Airlines

    19:15

    ORD

    8.6h

    10:50

    ZRH

    SMTWTFS
    Search

  12. LX780

    Swiss Airlines

    12:55

    ZRH

    1.3h

    14:15

    BRU

    SMTWTFS

  13. SK944

    Scandinavian Airlines

    19:45

    ORD

    8.5h

    11:15

    CPH

    SMTWTFS
    Search

  14. SK1593

    Scandinavian Airlines

    12:20

    CPH

    1.5h

    13:50

    BRU

    SM-WT-S

  15. BA1518

    British Airways

    20:40

    ORD

    7.7h

    10:20

    LHR

    SMTWTFS
    Search

  16. BA394

    British Airways

    11:50

    LHR

    1.2h

    14:00

    BRU

    SMTWTFS

  17. LH435

    Lufthansa

    21:25

    ORD

    8.5h

    12:55

    MUC

    SMTWTFS
    Search

  18. LH2288

    Lufthansa

    14:30

    MUC

    1.3h

    15:50

    BRU

    SMTWTFS

  19. AA098

    American Airlines

    22:45

    ORD

    7.5h

    12:15

    LHR

    SMTWTFS
    Search

  20. BA396

    British Airways

    16:55

    LHR

    1.2h

    19:05

    BRU

    SMTWTFS
Find more flights and airlines

Flight Info of Flights from O'Hare International Airport to Brussels

Cheapest round-trip ticket price

$611

Cheapest nonstop flight price

$344

Off-season for travel

April

Peak season for travel

October

FAQs for O'Hare International Airport to Brussels Flights

  • What is the transportation method from the main airport to downtown in Brussels?

    • The distance from Brussels National Airport to downtown is about 10km. It takes about 30 minutes by taxi.
    • The distance from Brussels South Charleroi Airport to downtown is about 43km. It takes about 1 hour by taxi.

Contact Us

About

Other Services

Payment Methods
Our Partners
Copyright © 2024 Trip.com Travel Singapore Pte. Ltd. All rights reserved
Site Operator: Trip.com Travel Singapore Pte. Ltd.