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O'Hare Intl. Airport to Des Moines International Airport flight

Explore the cheapest one-way and round-trip flights from O'Hare Intl. Airport to Des Moines International Airport over the next 90 days, with one-way fares from $120 and round-trip from $239. Based on Trip.com's latest 7-day flight data.

    • Cheapest nonstop
      ORD 10:53 PM
      1h 33m
      Nonstop
      DSM 12:26 AM
      Chicago - Des Moines | Thu, Nov 5 | American Airlines
      DSM 1:58 PM
      1h 46m
      Nonstop
      ORD 3:44 PM
      Des Moines - Chicago | Sat, Nov 7 | American Airlines
      $239 $674
      65% off
      65% off
      $674 $239
    • ORD 7:35 AM
      1h 37m
      Nonstop
      DSM 9:12 AM
      Chicago - Des Moines | Fri, Dec 18 | American Airlines
      DSM 5:30 AM
      1h 50m
      Nonstop
      ORD 7:20 AM
      Des Moines - Chicago | Sun, Dec 20 | American Airlines
      $343 $674
      49% off
      49% off
      $674 $343
    • ORD 11:51 AM
      1h 36m
      Nonstop
      DSM 1:27 PM
      Chicago - Des Moines | Thu, Nov 26 | American Airlines
      DSM 7:24 PM
      1h 50m
      Nonstop
      ORD 9:14 PM
      Des Moines - Chicago | Sun, Nov 29 | American Airlines
      $351 $674
      48% off
      48% off
      $674 $351
    • ORD 8:50 AM
      1h 42m
      Nonstop
      DSM 10:32 AM
      Chicago - Des Moines | Thu, Nov 26 | United Airlines
      DSM 9:25 AM
      1h 49m
      Nonstop
      ORD 11:14 AM
      Des Moines - Chicago | Sun, Nov 29 | American Airlines
      $403
      40% off
      $674 $403
    • ORD 7:35 AM
      1h 37m
      Nonstop
      DSM 9:12 AM
      Chicago - Des Moines | Wed, Dec 30 | American Airlines
      DSM 9:40 AM
      1h 53m
      Nonstop
      ORD 11:33 AM
      Des Moines - Chicago | Sat, Jan 2 | American Airlines
      $441
      35% off
      $674 $441
    • ORD 9:31 PM
      1h 46m
      Nonstop
      DSM 11:17 PM
      Chicago - Des Moines | Wed, Dec 30 | United Airlines
      DSM 8:00 AM
      1h 44m
      Nonstop
      ORD 9:44 AM
      Des Moines - Chicago | Sat, Jan 2 | United Airlines
      $491
      27% off
      $674 $491
    • ORD 6:20 AM
      3h 51m
      1 stop
      DSM 10:11 AM
      Chicago - Des Moines | Thu, Nov 5 | Delta Air Lines
      DSM 10:57 AM
      5h 50m
      1 stop
      MDW 4:47 PM
      Des Moines - Chicago | Sat, Nov 7 | Delta Air Lines
      $251
      63% off
      $674 $251
    • ORD 8:25 PM
      1h 30m
      Nonstop
      DSM 9:55 PM
      Chicago - Des Moines | Thu, Nov 5 | United Airlines
      DSM 10:57 AM
      3h 39m
      1 stop
      ORD 2:36 PM
      Des Moines - Chicago | Sat, Nov 7 | Delta Air Lines
      $290
      56% off
      $674 $290
    • ORD 9:59 AM
      6h 12m
      1 stop
      DSM 4:11 PM
      Chicago - Des Moines | Fri, Dec 18 | Delta Air Lines
      DSM 8:26 PM
      28h
      1 stop
      ORD 12:26 AM
      Des Moines - Chicago | Sun, Dec 20 | Frontier Airlines
      $329
      51% off
      $674 $329
    • CHI 1:00 PM
      17h 25m
      1 stop
      DSM 2:00 PM
      Chicago - Des Moines | Tue, Nov 3 | Normal Airline
      DSM 3:00 PM
      6h
      Nonstop
      CHI 4:00 PM
      Des Moines - Chicago | Thu, Nov 5 | Normal Airline
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    • Cheapest
      ORD 11:50 AM
      1h 45m
      Nonstop
      DSM 1:35 PM
      Chicago - Des Moines | Wed, Dec 9 | American Airlines
      $120 $184
      35% off
      35% off
      $184 $120
    • Cheapest
      ORD 10:53 PM
      1h 33m
      Nonstop
      DSM 12:26 AM
      Chicago - Des Moines | Thu, Nov 12 | American Airlines
      $120 $184
      35% off
      35% off
      $184 $120
    • ORD 10:45 PM
      1h 34m
      Nonstop
      DSM 12:19 AM
      Chicago - Des Moines | Tue, Dec 1 | American Airlines
      $123 $184
      33% off
      33% off
      $184 $123
    • ORD 6:20 AM
      4h 1m
      1 stop
      DSM 10:21 AM
      Chicago - Des Moines | Tue, Dec 1 | Delta Air Lines
      $124
      33% off
      $184 $124
    • ORD 6:20 AM
      4h 1m
      1 stop
      DSM 10:21 AM
      Chicago - Des Moines | Wed, Dec 9 | Delta Air Lines
      $126
      32% off
      $184 $126
    • ORD 6:23 AM
      3h 56m
      1 stop
      DSM 10:19 AM
      Chicago - Des Moines | Thu, Nov 12 | Delta Air Lines
      $127
      31% off
      $184 $127
    • ORD 10:53 PM
      1h 33m
      Nonstop
      DSM 12:26 AM
      Chicago - Des Moines | Fri, Nov 6 | American Airlines
      $143
      47% off
      $271 $143
    • ORD 5:42 PM
      3h 31m
      1 stop
      DSM 9:13 PM
      Chicago - Des Moines | Sat, Nov 21 | Delta Air Lines
      $144
      22% off
      $184 $144
    • ORD 5:19 PM
      1h 36m
      Nonstop
      DSM 6:55 PM
      Chicago - Des Moines | Sat, Nov 21 | American Airlines
      $145
      21% off
      $184 $145
    • CHI 1:00 PM
      17h 25m
      1 stop
      DSM 2:00 PM
      Chicago - Des Moines | Tue, Nov 3 | Normal Airline
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    • Cheapest nonstop
      ORD 11:50 AM
      1h 45m
      Nonstop
      DSM 1:35 PM
      Chicago - Des Moines | Wed, Dec 9 | American Airlines
      $120 $184
      35% off
      35% off
      $184 $120
    • ORD 10:53 PM
      1h 33m
      Nonstop
      DSM 12:26 AM
      Chicago - Des Moines | Thu, Nov 12 | American Airlines
      $120 $184
      35% off
      35% off
      $184 $120
    • ORD 10:45 PM
      1h 34m
      Nonstop
      DSM 12:19 AM
      Chicago - Des Moines | Tue, Dec 1 | American Airlines
      $123 $184
      33% off
      33% off
      $184 $123
    • ORD 10:53 PM
      1h 33m
      Nonstop
      DSM 12:26 AM
      Chicago - Des Moines | Fri, Nov 6 | American Airlines
      $143
      47% off
      $271 $143
    • ORD 5:19 PM
      1h 36m
      Nonstop
      DSM 6:55 PM
      Chicago - Des Moines | Sat, Nov 21 | American Airlines
      $145
      21% off
      $184 $145
    • ORD 11:00 PM
      1h 40m
      Nonstop
      DSM 12:40 AM
      Chicago - Des Moines | Sat, Dec 5 | American Airlines
      $150
      18% off
      $184 $150
    • ORD 5:21 PM
      1h 40m
      Nonstop
      DSM 7:01 PM
      Chicago - Des Moines | Sat, Dec 5 | American Airlines
      $150
      45% off
      $271 $150
    • ORD 5:21 PM
      1h 35m
      Nonstop
      DSM 6:56 PM
      Chicago - Des Moines | Tue, Dec 8 | American Airlines
      $159
      41% off
      $271 $159
    • ORD 5:21 PM
      1h 40m
      Nonstop
      DSM 7:01 PM
      Chicago - Des Moines | Sun, Dec 6 | American Airlines
      $176
      35% off
      $271 $176
    • CHI 1:00 PM
      17h 25m
      1 stop
      DSM 2:00 PM
      Chicago - Des Moines | Tue, Nov 3 | Normal Airline
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    • Cheapest nonstop
      ORD 10:53 PM
      1h 33m
      Nonstop
      DSM 12:26 AM
      Chicago - Des Moines | Fri, Nov 6 | American Airlines
      $143 $271
      47% off
      47% off
      $271 $143
    • ORD 5:21 PM
      1h 40m
      Nonstop
      DSM 7:01 PM
      Chicago - Des Moines | Sat, Dec 5 | American Airlines
      $150 $271
      45% off
      45% off
      $271 $150
    • ORD 5:21 PM
      1h 35m
      Nonstop
      DSM 6:56 PM
      Chicago - Des Moines | Tue, Dec 8 | American Airlines
      $159 $271
      41% off
      41% off
      $271 $159
    • ORD 5:21 PM
      1h 40m
      Nonstop
      DSM 7:01 PM
      Chicago - Des Moines | Sun, Dec 6 | American Airlines
      $176
      35% off
      $271 $176
    • ORD 9:00 PM
      1h 43m
      Nonstop
      DSM 10:43 PM
      Chicago - Des Moines | Mon, Jan 4 | American Airlines
      $201
      26% off
      $271 $201
    • ORD 9:00 PM
      1h 43m
      Nonstop
      DSM 10:43 PM
      Chicago - Des Moines | Wed, Dec 30 | American Airlines
      $201
      26% off
      $271 $201
    • ORD 9:25 PM
      1h 34m
      Nonstop
      DSM 10:59 PM
      Chicago - Des Moines | Fri, Nov 27 | United Airlines
      $206
      24% off
      $271 $206
    • ORD 10:43 PM
      1h 43m
      Nonstop
      DSM 12:26 AM
      Chicago - Des Moines | Sun, Jan 17 | American Airlines
      $217
      20% off
      $271 $217
    • ORD 10:53 PM
      1h 33m
      Nonstop
      DSM 12:26 AM
      Chicago - Des Moines | Mon, Nov 16 | American Airlines
      $241
      11% off
      $271 $241
    • CHI 1:00 PM
      17h 25m
      1 stop
      DSM 2:00 PM
      Chicago - Des Moines | Tue, Nov 3 | Normal Airline
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    • Cheapest nonstop
      ORD 10:53 PM
      1h 33m
      Nonstop
      DSM 12:26 AM
      Chicago - Des Moines | Fri, Nov 6 | American Airlines
      $143 $166
      14% off
      14% off
      $166 $143
    • ORD 6:20 AM
      3h 51m
      1 stop
      DSM 10:11 AM
      Chicago - Des Moines | Fri, Nov 6 | Delta Air Lines
      $147 $166
      11% off
      11% off
      $166 $147
    • CHI 1:00 PM
      17h 25m
      1 stop
      DSM 2:00 PM
      Chicago - Des Moines | Tue, Nov 3 | Normal Airline
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    • ORD 12:50 PM
      1h 24m
      Nonstop
      DSM 2:14 PM
      Chicago - Des Moines | Sun, Dec 6 | United Airlines
      $220 $308
      28% off
      28% off
      $308 $220
    • ORD 4:00 PM
      1h 28m
      Nonstop
      DSM 5:28 PM
      Chicago - Des Moines | Fri, Nov 6 | United Airlines
      $186 $308
      40% off
      40% off
      $308 $186
    • ORD 4:00 PM
      1h 28m
      Nonstop
      DSM 5:28 PM
      Chicago - Des Moines | Mon, Nov 16 | United Airlines
      $274 $308
      11% off
      11% off
      $308 $274
    • ORD 11:10 AM
      1h 29m
      Nonstop
      DSM 12:39 PM
      Chicago - Des Moines | Sat, Dec 5 | United Airlines
      $193
      37% off
      $308 $193
    • ORD 10:53 PM
      1h 33m
      Nonstop
      DSM 12:26 AM
      Chicago - Des Moines | Thu, Nov 12 | American Airlines
      $120
      35% off
      $184 $120
    • ORD 10:53 PM
      1h 33m
      Nonstop
      DSM 12:26 AM
      Chicago - Des Moines | Fri, Nov 6 | American Airlines
      $143
      47% off
      $271 $143
    • ORD 10:53 PM
      1h 33m
      Nonstop
      DSM 12:26 AM
      Chicago - Des Moines | Mon, Nov 16 | American Airlines
      $241
      11% off
      $271 $241
    • ORD 10:45 PM
      1h 34m
      Nonstop
      DSM 12:19 AM
      Chicago - Des Moines | Tue, Dec 1 | American Airlines
      $123
      33% off
      $184 $123
    • ORD 9:25 PM
      1h 34m
      Nonstop
      DSM 10:59 PM
      Chicago - Des Moines | Fri, Nov 27 | United Airlines
      $206
      24% off
      $271 $206
    • CHI 1:00 PM
      17h 25m
      1 stop
      DSM 2:00 PM
      Chicago - Des Moines | Tue, Nov 3 | Normal Airline
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Displayed flight fares from Chicago to Des Moines are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

Which airline offers the cheapest flights from O'Hare Intl. Airport to Des Moines International Airport?

The cheapest airline flying from O'Hare Intl. Airport to Des Moines International Airport is American Airlines (from $120) among 4 carriers operating this route. Based on Trip.com's latest 7-day flight data.

American Airlines
From $120
Delta Air Lines
From $123
United Airlines
From $154
Frontier Airlines
From $164

Find more flights and airlines

What is the flight schedule from O'Hare Intl. Airport to Des Moines International Airport?

Check the schedule for flights from Chicago to Des Moines and find the flight that best matches your travel plans.

Flight info.
Departure
Arrival
Weekly Schedule

  1. AA6284

    O'Hare Intl. Airport

    7:14 AM

    ORD

    1h 32m

    8:46 AM

    DSM

    S M T W T F S
    Search

  2. AA4548

    O'Hare Intl. Airport

    10:41 PM

    ORD

    1h 33m

    12:14 AM

    DSM

    S M T W T F S
    Search

  3. AA4711

    O'Hare Intl. Airport

    5:19 PM

    ORD

    1h 35m

    6:54 PM

    DSM

    S M T W T - S
    Search

  4. UA6041

    O'Hare Intl. Airport

    8:50 AM

    ORD

    1h 42m

    10:32 AM

    DSM

    S M T W T F S
    Search

  5. UA5412

    O'Hare Intl. Airport

    10:45 AM

    ORD

    1h 37m

    12:22 PM

    DSM

    - - - - - F -
    Search

  6. DL1306

    O'Hare Intl. Airport

    5:20 PM

    ORD

    1h 35m

    Nonstop

    6:55 PM

    MSP

    S M T W T - S
    Search

  7. DL5253

    Minneapolis-Saint Paul International Airport

    8:05 PM

    MSP

    1h 19m

    Nonstop

    9:24 PM

    DSM

    S M T W T F S

  8. DL1717

    O'Hare Intl. Airport

    6:00 AM

    ORD

    1h 36m

    Nonstop

    7:36 AM

    MSP

    S M T W T F S
    Search

  9. DL4998

    Minneapolis-Saint Paul International Airport

    9:00 AM

    MSP

    1h 20m

    Nonstop

    10:20 AM

    DSM

    S M T W T F S

  10. F91483

    O'Hare Intl. Airport

    7:35 AM

    ORD

    3h 4m

    Nonstop

    9:39 AM

    DEN

    S M T W T F S
    Search

  11. F91678

    Denver International Airport

    4:58 PM

    DEN

    1h 44m

    Nonstop

    7:42 PM

    DSM

    S - - - T - -
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About O'Hare Intl. Airport and Des Moines International Airport

Learn about O'Hare Intl. Airport (ORD) and Des Moines International Airport (DSM) — including location, terminals, transportation, and travel tips.

Flight distance 479.41 km
Cheapest one-way ticket price $120
Cheapest return ticket price $239

FAQs for O'Hare Intl. Airport to Des Moines International Airport Flights

  • How long is the flight from O'Hare Intl. Airport to Des Moines International Airport?

    O'Hare Intl. Airport to Des Moines International Airport takes about 54 minutes on average. Actual flight time may vary depending on route, weather and air traffic.
  • There are around 8 daily flights from O'Hare Intl. Airport (ORD) to Des Moines International Airport (DSM).
  • The earliest flight from O'Hare Intl. Airport to Des Moines International Airport departs at 07:17, and the last departs at 22:40, with about 16 flights per day. Flight times may change, so please check the latest departure and arrival times before you travel.
  • The route from O'Hare Intl. Airport (ORD) to Des Moines International Airport (DSM) is quite popular. Without considering departure times or holidays, tickets cost around $224 in November, the most expensive month to book this route.
  • The earliest flight departs from O'Hare Intl. Airport (ORD) at 09:06 and arrives in Des Moines International Airport (DSM) at 10:42.
  • The latest flight departs from O'Hare Intl. Airport (ORD) at 20:55 and arrives in Des Moines International Airport (DSM) at 22:23.
  • American Airlines is a very popular airline operating an average of 543 flights per month.
  • One-way flights from O'Hare Intl. Airport to Des Moines International Airport currently start from $120, and round-trip fares start from $239. The current lowest fare is a American Airlines flight departing on Wed, Dec 9; prices may vary depending on availability.
  • Yes. United Airlines and American Airlines operate direct flights from O'Hare Intl. Airport to Des Moines International Airport, with an average flight time of 51 minutes, and around 70 weekly flights. Actual flight frequency may vary by season.
  • Based on Trip.com flight data for departures within the next 30 days with at most one stop, the average one-way price from O'Hare Intl. Airport to Des Moines International Airport is $205. Prices may vary depending on the departure date, airline, and availability.
  • O'Hare Intl. Airport to Des Moines International Airport operates around 70 weekly flights, mainly by United Airlines and American Airlines. Actual frequency may vary during holidays and seasonal schedule adjustments.
  • Enter O'Hare Intl. Airport and Des Moines International Airport, select your departure date and number of passengers, then compare flights by price, flight duration, and baggage allowance. Once you've chosen a fare, review the change and refund rules, fill in passenger details, and pay to receive your booking confirmation.

Popular Destinations

Note: Prices shown on this page are estimated lowest price and include all taxes and fees found in the last 24 hours.

Book with no extra fees

Prices displayed in this page are all-inclusive prices (incl. taxes, fuel surcharge, civil aviation development fund, etc) with all fees confirmed before payment. Fees for luggage, meals, WLAN, or other additional services are also included as shown in the flight cards.

Real-time pricing updates

Prices, availability, and travel information on this page were updated within last 24 hours—even in real-time. The more popular the route, the more precise the data.

Change & Cancellation Policy

Trip.com displays flight cancellation and change policies for each flight ticket during the booking process, including fees and applicable conditions. Please check the following scenarios:
Voluntary cancellation/change:
To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy.
Cancellation/change due to a flight schedule change:
If the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.