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Santa Ana to Des Moines flight
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John Wayne Airport to Des Moines International Airport flight

Search for flights from Santa Ana to Des Moines and check out affordable one-way and round-trip options.

      • Cheapest nonstop
        SNA 12:41 PM
        3h 17m
        Nonstop
        DSM 5:58 PM
        Santa Ana - Des Moines | Sat, May 9 | Allegiant Air
        DSM 10:00 AM
        3h 51m
        Nonstop
        SNA 11:51 AM
        Des Moines - Santa Ana | Tue, May 12 | Allegiant Air
        $154 $423
        64% off
        64% off
        $423 $154
      • SNA 10:32 AM
        3h 19m
        Nonstop
        DSM 3:51 PM
        Santa Ana - Des Moines | Mon, May 25 | Allegiant Air
        DSM 8:00 AM
        3h 42m
        Nonstop
        SNA 9:42 AM
        Des Moines - Santa Ana | Fri, May 29 | Allegiant Air
        $209 $423
        51% off
        51% off
        $423 $209
      • SNA 10:32 AM
        3h 19m
        Nonstop
        DSM 3:51 PM
        Santa Ana - Des Moines | Fri, May 22 | Allegiant Air
        DSM 8:00 AM
        3h 42m
        Nonstop
        SNA 9:42 AM
        Des Moines - Santa Ana | Mon, May 25 | Allegiant Air
        $218 $423
        48% off
        48% off
        $423 $218
      • SNA 12:41 PM
        3h 17m
        Nonstop
        DSM 5:58 PM
        Santa Ana - Des Moines | Tue, May 19 | Allegiant Air
        DSM 8:00 AM
        3h 42m
        Nonstop
        SNA 9:42 AM
        Des Moines - Santa Ana | Fri, May 22 | Allegiant Air
        $238
        44% off
        $423 $238
      • SNA 12:41 PM
        3h 17m
        Nonstop
        DSM 5:58 PM
        Santa Ana - Des Moines | Sat, May 16 | Allegiant Air
        DSM 8:00 AM
        3h 42m
        Nonstop
        SNA 9:42 AM
        Des Moines - Santa Ana | Fri, May 22 | Allegiant Air
        $270
        36% off
        $423 $270
      • SNA 12:26 PM
        3h 17m
        Nonstop
        DSM 5:43 PM
        Santa Ana - Des Moines | Sat, May 2 | Allegiant Air
        DSM 9:45 AM
        3h 51m
        Nonstop
        SNA 11:36 AM
        Des Moines - Santa Ana | Tue, May 5 | Allegiant Air
        $284
        33% off
        $423 $284
      • SNA 6:45 AM
        5h 2m
        1 stop
        DSM 1:47 PM
        Santa Ana - Des Moines | Wed, May 20 | American Airlines
        DSM 5:45 AM
        5h 10m
        1 stop
        SNA 8:55 AM
        Des Moines - Santa Ana | Wed, May 27 | American Airlines
        $243
        43% off
        $423 $243
      • SNA 2:42 PM
        7h 17m
        1 stop
        DSM 11:59 PM
        Santa Ana - Des Moines | Thu, May 21 | American Airlines
        DSM 5:00 AM
        7h 41m
        1 stop
        SNA 10:41 AM
        Des Moines - Santa Ana | Thu, May 28 | American Airlines
        $243
        43% off
        $423 $243
      • SNA 4:15 PM
        5h 29m
        1 stop
        DSM 11:44 PM
        Santa Ana - Des Moines | Wed, May 20 | United Airlines
        DSM 5:45 AM
        5h 10m
        1 stop
        SNA 8:55 AM
        Des Moines - Santa Ana | Wed, May 27 | American Airlines
        $278
        34% off
        $423 $278
      • SNA 4:30 PM
        5h 19m
        1 stop
        DSM 11:49 PM
        Santa Ana - Des Moines | Wed, Jun 17 | American Airlines
        DSM 5:45 AM
        5h 10m
        1 stop
        SNA 8:55 AM
        Des Moines - Santa Ana | Wed, Jun 24 | American Airlines
        $296
        30% off
        $423 $296
      • SNA 1:00 PM
        17h 25m
        1 stop
        DSM 2:00 PM
        Santa Ana - Des Moines | Wed, Apr 29 | Normal Airline
        DSM 3:00 PM
        6h
        Nonstop
        SNA 4:00 PM
        Des Moines - Santa Ana | Fri, May 1 | Normal Airline
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      • Cheapest nonstop
        SNA 10:32 AM
        3h 19m
        Nonstop
        DSM 3:51 PM
        Santa Ana - Des Moines | Sat, May 23 | Allegiant Air
        $85 $230
        63% off
        63% off
        $230 $85
      • SNA 12:41 PM
        3h 17m
        Nonstop
        DSM 5:58 PM
        Santa Ana - Des Moines | Sun, May 10 | Allegiant Air
        $110 $230
        52% off
        52% off
        $230 $110
      • SNA 12:41 PM
        3h 17m
        Nonstop
        DSM 5:58 PM
        Santa Ana - Des Moines | Wed, May 20 | Allegiant Air
        $113 $230
        51% off
        51% off
        $230 $113
      • SNA 10:32 AM
        3h 19m
        Nonstop
        DSM 3:51 PM
        Santa Ana - Des Moines | Tue, Jun 2 | Allegiant Air
        $119
        48% off
        $230 $119
      • SNA 12:41 PM
        3h 17m
        Nonstop
        DSM 5:58 PM
        Santa Ana - Des Moines | Wed, May 13 | Allegiant Air
        $128
        44% off
        $230 $128
      • SNA 12:26 PM
        3h 17m
        Nonstop
        DSM 5:43 PM
        Santa Ana - Des Moines | Sun, May 3 | Allegiant Air
        $150
        35% off
        $230 $150
      • SNA 12:41 PM
        3h 17m
        Nonstop
        DSM 5:58 PM
        Santa Ana - Des Moines | Sun, May 17 | Allegiant Air
        $158
        31% off
        $230 $158
      • SNA 12:25 PM
        8h 7m
        1 stop
        DSM 10:32 PM
        Santa Ana - Des Moines | Thu, May 14 | Delta Air Lines
        $120
        48% off
        $230 $120
      • SNA 7:00 AM
        7h 15m
        1 stop
        DSM 4:15 PM
        Santa Ana - Des Moines | Fri, May 15 | United Airlines
        $159
        31% off
        $230 $159
      • SNA 8:45 AM
        5h 30m
        1 stop
        DSM 4:15 PM
        Santa Ana - Des Moines | Thu, May 14 | United Airlines
        $161
        30% off
        $230 $161
      • SNA 1:00 PM
        17h 25m
        1 stop
        DSM 2:00 PM
        Santa Ana - Des Moines | Wed, Apr 29 | Normal Airline
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Displayed flight fares from Santa Ana to Des Moines are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

Selected Airlines from John Wayne Airport to Des Moines International Airport

See which airlines fly from Santa Ana to Des Moines. Find the airline that best meets your travel needs by comparing prices and treat yourself to an enjoyable journey.

Allegiant Air
From $85
Delta Air Lines
From $120
United Airlines
From $159
American Airlines
From $172
Spirit Airlines
From $199
Frontier Airlines
From $257

Find more flights and airlines

Flight Schedule from John Wayne Airport to Des Moines International Airport

Check the schedule for flights from Santa Ana to Des Moines and find the flight that best matches your travel plans.

Flight info.
Departure
Arrival
Weekly Schedule

  1. G4477

    John Wayne Airport

    10:41 AM

    SNA

    3h 17m

    3:58 PM

    DSM

    S - - - T - -
    Search

  2. AA628

    John Wayne Airport

    6:45 AM

    SNA

    1h 34m

    Nonstop

    8:19 AM

    PHX

    S M T W T F S
    Search

  3. AA2029

    Phoenix Sky Harbor International Airport

    8:55 AM

    PHX

    2h 53m

    Nonstop

    1:48 PM

    DSM

    S M T W T F S

  4. UA489

    John Wayne Airport

    8:40 AM

    SNA

    2h 24m

    Nonstop

    12:04 PM

    DEN

    S M T W T F S
    Search

  5. UA1311

    Denver International Airport

    1:39 PM

    DEN

    1h 35m

    Nonstop

    4:14 PM

    DSM

    S M T W T F S

  6. DL2185

    John Wayne Airport

    8:00 AM

    SNA

    3h 39m

    Nonstop

    1:39 PM

    MSP

    S M T W T F S
    Search

  7. DL4913

    Minneapolis-Saint Paul International Airport

    2:40 PM

    MSP

    1h 17m

    Nonstop

    3:57 PM

    DSM

    S M T W T F S

  8. AA2908

    John Wayne Airport

    2:47 PM

    SNA

    4h 17m

    Nonstop

    9:04 PM

    ORD

    S M T W T F S
    Search

  9. AA1577

    O'Hare Intl. Airport

    10:29 PM

    ORD

    1h 20m

    Nonstop

    11:49 PM

    DSM

    S M T W T F S

  10. AA2590

    John Wayne Airport

    7:45 AM

    SNA

    4h 12m

    Nonstop

    1:57 PM

    ORD

    S M T W T F S
    Search

  11. AA4203

    O'Hare Intl. Airport

    2:59 PM

    ORD

    1h 32m

    Nonstop

    4:31 PM

    DSM

    S M T W T F S

  12. UA1352

    John Wayne Airport

    2:03 PM

    SNA

    4h 3m

    Nonstop

    8:06 PM

    ORD

    S M T W T F S
    Search

  13. UA5422

    O'Hare Intl. Airport

    9:45 PM

    ORD

    1h 39m

    Nonstop

    11:24 PM

    DSM

    S - - W T F -

  14. UA513

    John Wayne Airport

    6:50 AM

    SNA

    2h 24m

    Nonstop

    10:14 AM

    DEN

    S M T W T F -
    Search

  15. UA1311

    Denver International Airport

    1:39 PM

    DEN

    1h 35m

    Nonstop

    4:14 PM

    DSM

    S M T W T F S

  16. UA421

    John Wayne Airport

    11:15 AM

    SNA

    2h 19m

    Nonstop

    2:34 PM

    DEN

    S M T W T F S
    Search

  17. UA549

    Denver International Airport

    5:56 PM

    DEN

    1h 36m

    Nonstop

    8:32 PM

    DSM

    S M T W T F S

  18. AA2916

    John Wayne Airport

    2:42 PM

    SNA

    3h 8m

    Nonstop

    7:50 PM

    DFW

    S M T W T F S
    Search

  19. AA1371

    Dallas Fort Worth International Airport

    9:21 PM

    DFW

    1h 55m

    Nonstop

    11:16 PM

    DSM

    S M T W T F S
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John Wayne Airport to Des Moines International Airport Flights Info

Flight distance2,297.43 km
Cheapest one-way ticket price$85
Cheapest return ticket price$154

FAQs for John Wayne Airport to Des Moines International Airport Flights

  • How long is a flight from John Wayne Airport to Des Moines International Airport?

    It takes around 3 hours 19 minutes to fly from John Wayne Airport (sna) to Des Moines International Airport (dsm).
  • There are around 1 daily flights from John Wayne Airport (SNA) to Des Moines International Airport (DSM).
  • Tickets cost around $151 in May, making it the cheapest month to book. John Wayne Airport (SNA) to Des Moines International Airport (DSM) is a popular route, so don't forget to book your tickets in advance.
  • The route from John Wayne Airport (SNA) to Des Moines International Airport (DSM) is quite popular. Without considering departure times or holidays, tickets cost around $151 in May, the most expensive month to book this route.
  • Allegiant Air is a very popular airline operating an average of 44 flights per month.

Popular Destinations

Note: Prices shown on this page are estimated lowest price and include all taxes and fees found in the last 24 hours.

Book with no extra fees

Prices displayed in this page are all-inclusive prices (incl. taxes, fuel surcharge, civil aviation development fund, etc) with all fees confirmed before payment. Fees for luggage, meals, WLAN, or other additional services are also included as shown in the flight cards.

Real-time pricing updates

Prices, availability, and travel information on this page were updated within last 24 hours—even in real-time. The more popular the route, the more precise the data.

Change & Cancellation Policy

Trip.com displays flight cancellation and change policies for each flight ticket during the booking process, including fees and applicable conditions. Please check the following scenarios:
Voluntary cancellation/change:
To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy.
Cancellation/change due to a flight schedule change:
If the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.