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Santa Ana to Des Moines flight
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John Wayne Airport to Des Moines International Airport flight

Search for flights from Santa Ana to Des Moines and check out affordable one-way and round-trip options.

      • Cheapest nonstop
        SNA 12:27 PM
        3h 17m
        Nonstop
        DSM 5:44 PM
        Santa Ana - Des Moines | Sun, Sep 13 | Allegiant Air
        DSM 10:00 AM
        3h 37m
        Nonstop
        SNA 11:37 AM
        Des Moines - Santa Ana | Sun, Sep 20 | Allegiant Air
        $217 $526
        59% off
        59% off
        $526 $217
      • SNA 12:26 PM
        3h 17m
        Nonstop
        DSM 5:43 PM
        Santa Ana - Des Moines | Thu, Aug 27 | Allegiant Air
        DSM 10:00 AM
        3h 36m
        Nonstop
        SNA 11:36 AM
        Des Moines - Santa Ana | Sun, Aug 30 | Allegiant Air
        $217 $526
        59% off
        59% off
        $526 $217
      • SNA 9:32 AM
        3h 19m
        Nonstop
        DSM 2:51 PM
        Santa Ana - Des Moines | Sun, Aug 9 | Allegiant Air
        DSM 7:00 AM
        3h 42m
        Nonstop
        SNA 8:42 AM
        Des Moines - Santa Ana | Thu, Aug 13 | Allegiant Air
        $313 $526
        40% off
        40% off
        $526 $313
      • SNA 9:32 AM
        3h 19m
        Nonstop
        DSM 2:51 PM
        Santa Ana - Des Moines | Sun, Aug 16 | Allegiant Air
        DSM 10:00 AM
        3h 36m
        Nonstop
        SNA 11:36 AM
        Des Moines - Santa Ana | Sun, Aug 23 | Allegiant Air
        $338
        36% off
        $526 $338
      • SNA 11:15 AM
        24h 19m
        1 stop
        DSM 1:34 PM
        Santa Ana - Des Moines | Sun, Aug 16 | Frontier Airlines
        DSM 10:00 AM
        3h 36m
        Nonstop
        SNA 11:36 AM
        Des Moines - Santa Ana | Sun, Aug 23 | Allegiant Air
        $282
        46% off
        $526 $282
      • SNA 12:27 PM
        3h 17m
        Nonstop
        DSM 5:44 PM
        Santa Ana - Des Moines | Thu, Sep 10 | Allegiant Air
        DSM 5:45 AM
        5h 22m
        1 stop
        SNA 9:07 AM
        Des Moines - Santa Ana | Thu, Sep 17 | United Airlines
        $343
        35% off
        $526 $343
      • SNA 1:20 PM
        5h 26m
        1 stop
        DSM 8:46 PM
        Santa Ana - Des Moines | Wed, Aug 19 | American Airlines
        DSM 6:33 AM
        6h 17m
        1 stop
        SNA 10:50 AM
        Des Moines - Santa Ana | Wed, Aug 26 | American Airlines
        $356
        32% off
        $526 $356
      • SNA 1:20 PM
        5h 26m
        1 stop
        DSM 8:46 PM
        Santa Ana - Des Moines | Thu, Aug 27 | American Airlines
        DSM 5:30 AM
        5h 22m
        1 stop
        SNA 8:52 AM
        Des Moines - Santa Ana | Wed, Sep 2 | American Airlines
        $356
        32% off
        $526 $356
      • SNA 1:20 PM
        5h 26m
        1 stop
        DSM 8:46 PM
        Santa Ana - Des Moines | Tue, Aug 18 | American Airlines
        DSM 6:33 AM
        6h 17m
        1 stop
        SNA 10:50 AM
        Des Moines - Santa Ana | Tue, Aug 25 | American Airlines
        $360
        32% off
        $526 $360
      • SNA 8:10 AM
        6h 38m
        1 stop
        DSM 4:48 PM
        Santa Ana - Des Moines | Tue, Sep 15 | Delta Air Lines
        DSM 2:34 PM
        9h 30m
        1 stop
        SNA 10:04 PM
        Des Moines - Santa Ana | Tue, Sep 22 | Delta Air Lines
        $368
        30% off
        $526 $368
      • SNA 1:00 PM
        17h 25m
        1 stop
        DSM 2:00 PM
        Santa Ana - Des Moines | Fri, Aug 7 | Normal Airline
        DSM 3:00 PM
        6h
        Nonstop
        SNA 4:00 PM
        Des Moines - Santa Ana | Sun, Aug 9 | Normal Airline
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      • Cheapest nonstop
        SNA 12:26 PM
        3h 17m
        Nonstop
        DSM 5:43 PM
        Santa Ana - Des Moines | Sun, Aug 30 | Allegiant Air
        $115 $276
        57% off
        57% off
        $276 $115
      • SNA 2:29 PM
        6h 56m
        1 stop
        DSM 11:25 PM
        Santa Ana - Des Moines | Mon, Aug 17 | American Airlines
        $174 $276
        37% off
        37% off
        $276 $174
      • SNA 12:14 PM
        8h 58m
        1 stop
        DSM 11:12 PM
        Santa Ana - Des Moines | Thu, Oct 1 | American Airlines
        $175 $276
        37% off
        37% off
        $276 $175
      • SNA 2:29 PM
        6h 56m
        1 stop
        DSM 11:25 PM
        Santa Ana - Des Moines | Wed, Aug 19 | American Airlines
        $178
        36% off
        $276 $178
      • SNA 2:29 PM
        6h 47m
        1 stop
        DSM 11:16 PM
        Santa Ana - Des Moines | Sat, Aug 29 | American Airlines
        $178
        36% off
        $276 $178
      • SNA 12:23 PM
        6h 23m
        1 stop
        DSM 8:46 PM
        Santa Ana - Des Moines | Tue, Aug 25 | American Airlines
        $179
        35% off
        $276 $179
      • SNA 11:45 AM
        8h 52m
        1 stop
        DSM 10:37 PM
        Santa Ana - Des Moines | Tue, Aug 25 | Delta Air Lines
        $185
        33% off
        $276 $185
      • SNA 3:21 PM
        6h 59m
        1 stop
        DSM 12:20 AM
        Santa Ana - Des Moines | Thu, Aug 20 | American Airlines
        $189
        32% off
        $276 $189
      • SNA 6:45 AM
        9h 7m
        1 stop
        DSM 5:52 PM
        Santa Ana - Des Moines | Wed, Sep 2 | American Airlines
        $193
        30% off
        $276 $193
      • SNA 2:29 PM
        6h 56m
        1 stop
        DSM 11:25 PM
        Santa Ana - Des Moines | Mon, Aug 31 | American Airlines
        $193
        30% off
        $276 $193
      • SNA 1:00 PM
        17h 25m
        1 stop
        DSM 2:00 PM
        Santa Ana - Des Moines | Fri, Aug 7 | Normal Airline
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Selected Airlines from John Wayne Airport to Des Moines International Airport

See which airlines fly from Santa Ana to Des Moines. Find the airline that best meets your travel needs by comparing prices and treat yourself to an enjoyable journey.

Allegiant Air
From $115
American Airlines
From $174
Delta Air Lines
From $185
Frontier Airlines
From $211
United Airlines
From $211
Breeze Airways
From $543

Find more flights and airlines

Flight Schedule from John Wayne Airport to Des Moines International Airport

Check the schedule for flights from Santa Ana to Des Moines and find the flight that best matches your travel plans.

Flight info.
Departure
Arrival
Weekly Schedule

  1. G42101

    John Wayne Airport

    9:28 AM

    SNA

    3h 14m

    2:42 PM

    DSM

    - - - W - - S
    Search

  2. AA2463

    John Wayne Airport

    4:55 PM

    SNA

    1h 29m

    Nonstop

    6:24 PM

    PHX

    S M T W T F S
    Search

  3. AA1462

    Phoenix Sky Harbor International Airport

    3:57 PM

    PHX

    2h 49m

    Nonstop

    8:46 PM

    DSM

    - - - W - - S

  4. UA1534

    John Wayne Airport

    1:08 PM

    SNA

    2h 23m

    Nonstop

    4:31 PM

    DEN

    - M - - - - -
    Search

  5. UA549

    Denver International Airport

    5:56 PM

    DEN

    1h 36m

    Nonstop

    8:32 PM

    DSM

    S M T W T F S

  6. UA489

    John Wayne Airport

    8:45 AM

    SNA

    2h 23m

    Nonstop

    12:08 PM

    DEN

    S M T W T F S
    Search

  7. UA1311

    Denver International Airport

    1:39 PM

    DEN

    1h 35m

    Nonstop

    4:14 PM

    DSM

    S M T W T F S

  8. UA1048

    John Wayne Airport

    4:08 PM

    SNA

    2h 20m

    Nonstop

    7:28 PM

    DEN

    - M - - - - -
    Search

  9. UA5389

    Denver International Airport

    9:00 PM

    DEN

    1h 39m

    Nonstop

    11:39 PM

    DSM

    - M T W T F S

  10. DL2061

    John Wayne Airport

    1:00 PM

    SNA

    3h 42m

    Nonstop

    6:42 PM

    MSP

    S - - W T - S
    Search

  11. DL5253

    Minneapolis-Saint Paul International Airport

    8:05 PM

    MSP

    1h 19m

    Nonstop

    9:24 PM

    DSM

    S M T W T F S

  12. AA2454

    John Wayne Airport

    12:23 PM

    SNA

    1h 29m

    Nonstop

    1:52 PM

    PHX

    S M T W T F S
    Search

  13. AA1336

    Phoenix Sky Harbor International Airport

    3:57 PM

    PHX

    2h 49m

    Nonstop

    8:46 PM

    DSM

    S M T - T F -

  14. AA2465

    John Wayne Airport

    2:29 PM

    SNA

    3h 21m

    Nonstop

    7:50 PM

    DFW

    S M T W T F S
    Search

  15. AA1371

    Dallas Fort Worth International Airport

    9:29 PM

    DFW

    1h 56m

    Nonstop

    11:25 PM

    DSM

    S M T W T F S

  16. AA3151

    John Wayne Airport

    3:21 PM

    SNA

    4h 37m

    Nonstop

    9:58 PM

    ORD

    S M T W T F S
    Search

  17. AA4460

    O'Hare Intl. Airport

    11:00 PM

    ORD

    1h 35m

    Nonstop

    12:35 AM

    DSM

    S M T W T F S

  18. UA2843

    John Wayne Airport

    11:30 AM

    SNA

    2h 10m

    Nonstop

    2:40 PM

    DEN

    S M T W T F S
    Search

  19. UA549

    Denver International Airport

    5:56 PM

    DEN

    1h 36m

    Nonstop

    8:32 PM

    DSM

    S M T W T F S
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John Wayne Airport to Des Moines International Airport Flights Info

Flight distance 2,297.43 km
Cheapest one-way ticket price $115
Cheapest return ticket price $217

FAQs for John Wayne Airport to Des Moines International Airport Flights

  • How long is a flight from John Wayne Airport to Des Moines International Airport?

    It takes around 3 hours 19 minutes to fly from John Wayne Airport (sna) to Des Moines International Airport (dsm).
  • There are around 1 daily flights from John Wayne Airport (SNA) to Des Moines International Airport (DSM).
  • Tickets cost around $305 in August, making it the cheapest month to book. John Wayne Airport (SNA) to Des Moines International Airport (DSM) is a popular route, so don't forget to book your tickets in advance.
  • The route from John Wayne Airport (SNA) to Des Moines International Airport (DSM) is quite popular. Without considering departure times or holidays, tickets cost around $304 in August, the most expensive month to book this route.
  • Allegiant Air is a very popular airline operating an average of 44 flights per month.

Popular Destinations

Note: Prices shown on this page are estimated lowest price and include all taxes and fees found in the last 24 hours.

Book with no extra fees

Prices displayed in this page are all-inclusive prices (incl. taxes, fuel surcharge, civil aviation development fund, etc) with all fees confirmed before payment. Fees for luggage, meals, WLAN, or other additional services are also included as shown in the flight cards.

Real-time pricing updates

Prices, availability, and travel information on this page were updated within last 24 hours—even in real-time. The more popular the route, the more precise the data.

Change & Cancellation Policy

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Voluntary cancellation/change:
To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy.
Cancellation/change due to a flight schedule change:
If the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.