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St. Louis Lambert International Airport to San Diego International Airport flight

Explore the cheapest one-way and round-trip flights from St. Louis Lambert International Airport to San Diego International Airport over the next 90 days, with one-way fares from £56 and round-trip from £110. Based on Trip.com's latest 7-day flight data.

    • STL 7:54 PM
      6h 4m
      1 stop
      SAN 11:58 PM
      St. Louis - San Diego | Sat, Dec 5 | Frontier Airlines
      SAN 11:14 AM
      21h 43m
      1 stop
      STL 10:57 AM
      San Diego - St. Louis | Fri, Dec 11 | Frontier Airlines
      £110 £488
      77% off
      77% off
      £488 £110
    • STL 4:18 PM
      9h 39m
      1 stop
      SAN 11:57 PM
      St. Louis - San Diego | Wed, Nov 18 | Frontier Airlines
      SAN 5:29 PM
      15h 34m
      1 stop
      STL 11:03 AM
      San Diego - St. Louis | Sun, Nov 22 | Frontier Airlines
      £112 £488
      77% off
      77% off
      £488 £112
    • STL 7:54 PM
      16h 25m
      1 stop
      SAN 10:19 AM
      St. Louis - San Diego | Fri, Dec 11 | Frontier Airlines
      SAN 6:30 AM
      26h 27m
      1 stop
      STL 10:57 AM
      San Diego - St. Louis | Sun, Dec 13 | Frontier Airlines
      £118 £488
      76% off
      76% off
      £488 £118
    • STL 3:04 PM
      10h 53m
      1 stop
      SAN 11:57 PM
      St. Louis - San Diego | Sat, Nov 21 | Frontier Airlines
      SAN 6:30 AM
      26h 33m
      1 stop
      STL 11:03 AM
      San Diego - St. Louis | Sun, Nov 22 | Frontier Airlines
      £132
      73% off
      £488 £132
    • STL 7:59 PM
      5h 58m
      1 stop
      SAN 11:57 PM
      St. Louis - San Diego | Sat, Nov 14 | Frontier Airlines
      SAN 5:29 PM
      15h 34m
      1 stop
      STL 11:03 AM
      San Diego - St. Louis | Fri, Nov 20 | Frontier Airlines
      £135
      72% off
      £488 £135
    • STL 7:58 PM
      5h 59m
      1 stop
      SAN 11:57 PM
      St. Louis - San Diego | Fri, Dec 4 | Frontier Airlines
      SAN 6:30 AM
      26h 27m
      1 stop
      STL 10:57 AM
      San Diego - St. Louis | Sun, Dec 6 | Frontier Airlines
      £136
      72% off
      £488 £136
    • STL 7:59 PM
      21h 59m
      1 stop
      SAN 3:58 PM
      St. Louis - San Diego | Mon, Nov 16 | Frontier Airlines
      SAN 6:25 AM
      26h 20m
      1 stop
      STL 10:45 AM
      San Diego - St. Louis | Wed, Nov 18 | Frontier Airlines
      £147
      70% off
      £488 £147
    • STL 3:04 PM
      10h 53m
      1 stop
      SAN 11:57 PM
      St. Louis - San Diego | Wed, Nov 25 | Frontier Airlines
      SAN 6:30 AM
      26h 36m
      1 stop
      STL 11:06 AM
      San Diego - St. Louis | Tue, Dec 1 | Frontier Airlines
      £147
      70% off
      £488 £147
    • STL 5:51 PM
      7h 48m
      1 stop
      SAN 11:39 PM
      St. Louis - San Diego | Wed, Dec 2 | Delta Air Lines
      SAN 10:10 PM
      9h 13m
      1 stop
      STL 9:23 AM
      San Diego - St. Louis | Wed, Dec 9 | Delta Air Lines
      £166
      66% off
      £488 £166
    • STL 1:00 PM
      17h 25m
      1 stop
      SAN 2:00 PM
      St. Louis - San Diego | Sun, Nov 1 | Normal Airline
      SAN 3:00 PM
      6h
      Nonstop
      STL 4:00 PM
      San Diego - St. Louis | Tue, Nov 3 | Normal Airline
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    • Cheapest
      STL 3:04 PM
      10h 53m
      1 stop
      SAN 11:57 PM
      St. Louis - San Diego | Mon, Nov 23 | Frontier Airlines
      £56 £178
      69% off
      69% off
      £178 £56
    • STL 3:04 PM
      10h 53m
      1 stop
      SAN 11:57 PM
      St. Louis - San Diego | Sat, Nov 21 | Frontier Airlines
      £65 £178
      63% off
      63% off
      £178 £65
    • STL 7:59 PM
      5h 58m
      1 stop
      SAN 11:57 PM
      St. Louis - San Diego | Mon, Nov 9 | Frontier Airlines
      £67 £178
      62% off
      62% off
      £178 £67
    • STL 7:59 PM
      5h 58m
      1 stop
      SAN 11:57 PM
      St. Louis - San Diego | Sat, Nov 7 | Frontier Airlines
      £69
      61% off
      £178 £69
    • STL 7:54 PM
      6h 4m
      1 stop
      SAN 11:58 PM
      St. Louis - San Diego | Fri, Dec 11 | Frontier Airlines
      £70
      61% off
      £178 £70
    • STL 7:54 PM
      6h 4m
      1 stop
      SAN 11:58 PM
      St. Louis - San Diego | Wed, Dec 16 | Frontier Airlines
      £71
      60% off
      £178 £71
    • STL 11:40 AM
      6h 28m
      1 stop
      SAN 4:08 PM
      St. Louis - San Diego | Thu, Nov 19 | Frontier Airlines
      £73
      59% off
      £178 £73
    • STL 4:18 PM
      9h 39m
      1 stop
      SAN 11:57 PM
      St. Louis - San Diego | Wed, Nov 18 | Frontier Airlines
      £74
      57% off
      £178 £74
    • STL 7:59 PM
      21h 59m
      1 stop
      SAN 3:58 PM
      St. Louis - San Diego | Mon, Nov 16 | Frontier Airlines
      £75
      57% off
      £178 £75
    • STL 1:00 PM
      17h 25m
      1 stop
      SAN 2:00 PM
      St. Louis - San Diego | Sun, Nov 1 | Normal Airline
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    • STL 7:59 PM
      5h 58m
      1 stop
      SAN 11:57 PM
      St. Louis - San Diego | Mon, Nov 9 | Frontier Airlines
      £67 £635
      89% off
      89% off
      £635 £67
    • STL 7:59 PM
      5h 58m
      1 stop
      SAN 11:57 PM
      St. Louis - San Diego | Sat, Nov 7 | Frontier Airlines
      £69 £635
      89% off
      89% off
      £635 £69
    • STL 7:02 PM
      6h 56m
      1 stop
      SAN 11:58 PM
      St. Louis - San Diego | Fri, Jan 15 | Frontier Airlines
      £164 £635
      74% off
      74% off
      £635 £164
    • STL 2:17 PM
      6h 8m
      1 stop
      SAN 6:25 PM
      St. Louis - San Diego | Tue, Dec 1 | American Airlines
      £165
      74% off
      £635 £165
    • STL 1:00 PM
      17h 25m
      1 stop
      SAN 2:00 PM
      St. Louis - San Diego | Sun, Nov 1 | Normal Airline
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    • STL 2:20 PM
      5h 44m
      1 stop
      SAN 6:04 PM
      St. Louis - San Diego | Mon, Nov 9 | Delta Air Lines
      £159 £635
      75% off
      75% off
      £635 £159
    • STL 2:28 PM
      5h 55m
      1 stop
      SAN 6:23 PM
      St. Louis - San Diego | Sat, Nov 7 | American Airlines
      £108 £635
      83% off
      83% off
      £635 £108
    • STL 2:28 PM
      5h 55m
      1 stop
      SAN 6:23 PM
      St. Louis - San Diego | Mon, Nov 9 | American Airlines
      £299 £635
      53% off
      53% off
      £635 £299
    • STL 2:28 PM
      5h 56m
      1 stop
      SAN 6:24 PM
      St. Louis - San Diego | Fri, Jan 15 | American Airlines
      £247
      61% off
      £635 £247
    • STL 7:59 PM
      5h 58m
      1 stop
      SAN 11:57 PM
      St. Louis - San Diego | Mon, Nov 9 | Frontier Airlines
      £67
      62% off
      £178 £67
    • STL 7:59 PM
      5h 58m
      1 stop
      SAN 11:57 PM
      St. Louis - San Diego | Sat, Nov 7 | Frontier Airlines
      £69
      61% off
      £178 £69
    • STL 7:54 PM
      6h 4m
      1 stop
      SAN 11:58 PM
      St. Louis - San Diego | Fri, Dec 11 | Frontier Airlines
      £70
      61% off
      £178 £70
    • STL 7:54 PM
      6h 4m
      1 stop
      SAN 11:58 PM
      St. Louis - San Diego | Wed, Dec 16 | Frontier Airlines
      £71
      60% off
      £178 £71
    • STL 7:54 PM
      6h 4m
      1 stop
      SAN 11:58 PM
      St. Louis - San Diego | Sat, Dec 12 | Frontier Airlines
      £75
      57% off
      £178 £75
    • STL 1:00 PM
      17h 25m
      1 stop
      SAN 2:00 PM
      St. Louis - San Diego | Sun, Nov 1 | Normal Airline
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Displayed flight fares from St. Louis to San Diego are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

Which airline offers the cheapest flights from St. Louis Lambert International Airport to San Diego International Airport?

The cheapest airline flying from St. Louis Lambert International Airport to San Diego International Airport is Frontier Airlines (from £56) among 5 carriers operating this route. Based on Trip.com's latest 7-day flight data.

Frontier Airlines
From £56
Delta Air Lines
From £97
Alaska Airlines
From £99
American Airlines
From £108
United Airlines
From £138

Find more flights and airlines

What is the flight schedule from St. Louis Lambert International Airport to San Diego International Airport?

Check the schedule for flights from St. Louis to San Diego and find the flight that best matches your travel plans.

Flight info.
Departure
Arrival
Weekly Schedule

  1. F94567

    St. Louis Lambert International Airport

    7:54 PM

    STL

    2h 31m

    Nonstop

    9:25 PM

    DEN

    S - T - T F -
    Search

  2. F92817

    Denver International Airport

    2:28 PM

    DEN

    2h 30m

    Nonstop

    3:58 PM

    SAN

    S M T W T F S

  3. AA2269

    St. Louis Lambert International Airport

    6:54 PM

    STL

    2h 1m

    Nonstop

    8:55 PM

    DFW

    S M T W T - S
    Search

  4. AA2568

    Dallas Fort Worth International Airport

    10:32 PM

    DFW

    3h 6m

    Nonstop

    11:38 PM

    SAN

    S - T W T - S

  5. AA3409

    St. Louis Lambert International Airport

    6:00 AM

    STL

    1h 34m

    Nonstop

    7:34 AM

    ORD

    S M T W T - -
    Search

  6. AA1543

    O'Hare Intl. Airport

    9:21 PM

    ORD

    4h 23m

    Nonstop

    11:44 PM

    SAN

    S M T W T - S

  7. AA2261

    St. Louis Lambert International Airport

    5:40 AM

    STL

    2h

    Nonstop

    7:40 AM

    DFW

    S M T W T F -
    Search

  8. AA3319

    Dallas Fort Worth International Airport

    9:00 AM

    DFW

    3h 16m

    Nonstop

    10:16 AM

    SAN

    S M T W T - S

  9. F93107

    St. Louis Lambert International Airport

    1:28 PM

    STL

    3h 44m

    Nonstop

    3:12 PM

    LAS

    S - - W T - S
    Search

  10. F91469

    Harry Reid Intl. Airport

    6:15 PM

    LAS

    1h 20m

    Nonstop

    7:35 PM

    SAN

    S - - W T - S

  11. AA3111

    St. Louis Lambert International Airport

    11:35 AM

    STL

    1h 25m

    Nonstop

    1:00 PM

    ORD

    S M T W T - S
    Search

  12. AA3032

    O'Hare Intl. Airport

    4:45 PM

    ORD

    4h 47m

    Nonstop

    7:32 PM

    SAN

    S M T W T - S

  13. DL1626

    St. Louis Lambert International Airport

    6:45 AM

    STL

    1h 33m

    Nonstop

    9:18 AM

    DTW

    S M T W T F S
    Search

  14. DL761

    Detroit Metropolitan Wayne County Airport

    12:15 PM

    DTW

    5h 6m

    Nonstop

    2:21 PM

    SAN

    S M T W T F S

  15. AS615

    St. Louis Lambert International Airport

    6:00 AM

    STL

    4h 36m

    Nonstop

    8:36 AM

    SEA

    S M T W T - S
    Search

  16. AS650

    Seattle Tacoma Intl. Airport

    11:43 AM

    SEA

    3h 4m

    Nonstop

    2:47 PM

    SAN

    S M T W T F S

  17. F94567

    St. Louis Lambert International Airport

    7:54 PM

    STL

    2h 31m

    Nonstop

    9:25 PM

    DEN

    S - T - T F -
    Search

  18. F92711

    Denver International Airport

    10:29 PM

    DEN

    2h 28m

    Nonstop

    11:57 PM

    SAN

    S M T W T F S
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About St. Louis Lambert International Airport and San Diego International Airport

Learn about St. Louis Lambert International Airport (STL) and San Diego International Airport (SAN) — including location, terminals, transportation, and travel tips.

Flight distance 2,504.95 km
Cheapest one-way ticket price £56
Cheapest return ticket price £110

FAQs for St. Louis Lambert International Airport to San Diego International Airport Flights

  • How long is the flight from St. Louis Lambert International Airport to San Diego International Airport?

    St. Louis Lambert International Airport to San Diego International Airport takes about 4 hours 21 minutes on average. Actual flight time may vary depending on route, weather and air traffic.
  • There are around 2 daily flights from St. Louis Lambert International Airport (STL) to San Diego International Airport (SAN).
  • The earliest flight from St. Louis Lambert International Airport to San Diego International Airport departs at 08:00, and the last departs at 13:45, with about 5 flights per day. Flight times may change, so please check the latest departure and arrival times before you travel.
  • The route from St. Louis Lambert International Airport (STL) to San Diego International Airport (SAN) is quite popular. Without considering departure times or holidays, tickets cost around £484 in October, the most expensive month to book this route.
  • The earliest flight departs from St. Louis Lambert International Airport (STL) at 05:30 and arrives in San Diego International Airport (SAN) at 09:15.
  • The latest flight departs from St. Louis Lambert International Airport (STL) at 17:34 and arrives in San Diego International Airport (SAN) at 22:27.
    • The distance from San Diego International Airport to downtown is about 3 km. It takes about 20 minutes by taxi.
    • The distance from McClellan-Palomar Airport to downtown is about 47 km. It takes about 1 hour by taxi.
  • One-way flights from St. Louis Lambert International Airport to San Diego International Airport currently start from £56, and round-trip fares start from £110. The current lowest fare is a Frontier Airlines flight departing on Mon, Nov 23; prices may vary depending on availability.
  • Based on Trip.com flight data for departures within the next 30 days with at most one stop, the average one-way price from St. Louis Lambert International Airport to San Diego International Airport is £187. Prices may vary depending on the departure date, airline, and availability.
  • St. Louis Lambert International Airport to San Diego International Airport operates around 12 weekly flights, mainly by United Airlines. Actual frequency may vary during holidays and seasonal schedule adjustments.
  • Enter St. Louis Lambert International Airport and San Diego International Airport, select your departure date and number of passengers, then compare flights by price, flight duration, and baggage allowance. Once you've chosen a fare, review the change and refund rules, fill in passenger details, and pay to receive your booking confirmation.

Popular Destinations

Note: Prices shown on this page are estimated lowest price and include all taxes and fees found in the last 24 hours.

Book with no extra fees

Prices displayed in this page are all-inclusive prices (incl. taxes, fuel surcharge, civil aviation development fund, etc) with all fees confirmed before payment. Fees for luggage, meals, WLAN, or other additional services are also included as shown in the flight cards.

Real-time pricing updates

Prices, availability, and travel information on this page were updated within last 24 hours—even in real-time. The more popular the route, the more precise the data.

Change & Cancellation Policy

Trip.com displays flight cancellation and change policies for each flight ticket during the booking process, including fees and applicable conditions. Please check the following scenarios:
Voluntary cancellation/change:
To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy.
Cancellation/change due to a flight schedule change:
If the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.