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Mcghee Tyson Airport to O'Hare Intl. Airport flight

Explore the cheapest one-way and round-trip flights from Mcghee Tyson Airport to O'Hare Intl. Airport over the next 90 days, with one-way fares from $127 and round-trip from $180. Based on Trip.com's latest 7-day flight data.

    • Cheapest nonstop
      TYS 8:52 PM
      2h 6m
      Nonstop
      ORD 9:58 PM
      Knoxville - Chicago | Fri, Nov 13 | American Airlines
      MDW 4:31 PM
      1h 30m
      Nonstop
      TYS 7:01 PM
      Chicago - Knoxville | Mon, Nov 16 | Allegiant Air
      $219 $372
      41% off
      41% off
      $372 $219
    • TYS 4:24 PM
      2h 5m
      Nonstop
      ORD 5:29 PM
      Knoxville - Chicago | Sat, Dec 12 | American Airlines
      ORD 1:47 PM
      1h 50m
      Nonstop
      TYS 4:37 PM
      Chicago - Knoxville | Mon, Dec 14 | American Airlines
      $253 $372
      32% off
      32% off
      $372 $253
    • TYS 4:38 PM
      2h 2m
      Nonstop
      ORD 5:40 PM
      Knoxville - Chicago | Thu, Oct 29 | American Airlines
      ORD 8:12 AM
      1h 49m
      Nonstop
      TYS 11:01 AM
      Chicago - Knoxville | Mon, Nov 2 | American Airlines
      $281 $372
      24% off
      24% off
      $372 $281
    • TYS 5:07 PM
      2h 4m
      Nonstop
      ORD 6:11 PM
      Knoxville - Chicago | Fri, Dec 11 | American Airlines
      ORD 1:53 PM
      1h 50m
      Nonstop
      TYS 4:43 PM
      Chicago - Knoxville | Sun, Dec 13 | American Airlines
      $283
      24% off
      $372 $283
    • TYS 11:28 AM
      2h 12m
      Nonstop
      ORD 12:40 PM
      Knoxville - Chicago | Sat, Nov 21 | American Airlines
      ORD 4:08 PM
      1h 44m
      Nonstop
      TYS 6:52 PM
      Chicago - Knoxville | Tue, Nov 24 | American Airlines
      $305
      18% off
      $372 $305
    • TYS 7:22 PM
      5h 32m
      1 stop
      ORD 11:54 PM
      Knoxville - Chicago | Fri, Nov 13 | Delta Air Lines
      MDW 4:31 PM
      1h 30m
      Nonstop
      TYS 7:01 PM
      Chicago - Knoxville | Mon, Nov 16 | Allegiant Air
      $180
      52% off
      $372 $180
    • TYS 6:17 PM
      6h 39m
      1 stop
      ORD 11:56 PM
      Knoxville - Chicago | Sat, Dec 12 | Delta Air Lines
      ORD 5:30 AM
      4h 57m
      1 stop
      TYS 11:27 AM
      Chicago - Knoxville | Mon, Dec 14 | Delta Air Lines
      $253
      32% off
      $372 $253
    • TYS 8:50 PM
      2h 9m
      Nonstop
      ORD 9:59 PM
      Knoxville - Chicago | Thu, Nov 19 | American Airlines
      ORD 6:49 PM
      4h 10m
      1 stop
      TYS 11:59 PM
      Chicago - Knoxville | Sat, Nov 21 | American Airlines
      $264
      28% off
      $372 $264
    • TYS 7:22 PM
      5h 32m
      1 stop
      ORD 11:54 PM
      Knoxville - Chicago | Thu, Nov 19 | Delta Air Lines
      MDW 1:31 PM
      5h 34m
      1 stop
      TYS 8:05 PM
      Chicago - Knoxville | Sat, Nov 21 | Delta Air Lines
      $267
      28% off
      $372 $267
    • TYS 1:00 PM
      17h 25m
      1 stop
      CHI 2:00 PM
      Knoxville - Chicago | Wed, Oct 28 | Normal Airline
      CHI 3:00 PM
      6h
      Nonstop
      TYS 4:00 PM
      Chicago - Knoxville | Fri, Oct 30 | Normal Airline
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    • Cheapest
      TYS 8:48 PM
      2h 12m
      Nonstop
      ORD 10:00 PM
      Knoxville - Chicago | Thu, Dec 31 | American Airlines
      $127 $152
      16% off
      16% off
      $152 $127
    • Cheapest
      TYS 6:00 AM
      2h 26m
      Nonstop
      ORD 7:26 AM
      Knoxville - Chicago | Thu, Dec 24 | American Airlines
      $127 $152
      16% off
      16% off
      $152 $127
    • Cheapest
      TYS 8:48 PM
      2h 12m
      Nonstop
      ORD 10:00 PM
      Knoxville - Chicago | Tue, Dec 29 | American Airlines
      $127 $152
      16% off
      16% off
      $152 $127
    • Cheapest
      TYS 8:48 PM
      2h 12m
      Nonstop
      ORD 10:00 PM
      Knoxville - Chicago | Wed, Dec 23 | American Airlines
      $127
      16% off
      $152 $127
    • Cheapest
      TYS 8:51 PM
      2h 9m
      Nonstop
      ORD 10:00 PM
      Knoxville - Chicago | Wed, Jan 6 | American Airlines
      $127
      16% off
      $152 $127
    • Cheapest
      TYS 8:51 PM
      2h 9m
      Nonstop
      ORD 10:00 PM
      Knoxville - Chicago | Thu, Jan 7 | American Airlines
      $127
      16% off
      $152 $127
    • Cheapest
      TYS 8:48 PM
      2h 12m
      Nonstop
      ORD 10:00 PM
      Knoxville - Chicago | Tue, Dec 22 | American Airlines
      $127
      16% off
      $152 $127
    • Cheapest
      TYS 8:48 PM
      2h 12m
      Nonstop
      ORD 10:00 PM
      Knoxville - Chicago | Mon, Dec 28 | American Airlines
      $127
      16% off
      $152 $127
    • Cheapest
      TYS 6:00 AM
      2h 26m
      Nonstop
      ORD 7:26 AM
      Knoxville - Chicago | Fri, Dec 25 | American Airlines
      $127
      16% off
      $152 $127
    • TYS 1:00 PM
      17h 25m
      1 stop
      CHI 2:00 PM
      Knoxville - Chicago | Wed, Oct 28 | Normal Airline
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    • Cheapest nonstop
      TYS 8:48 PM
      2h 12m
      Nonstop
      ORD 10:00 PM
      Knoxville - Chicago | Thu, Dec 31 | American Airlines
      $127 $152
      16% off
      16% off
      $152 $127
    • TYS 6:00 AM
      2h 26m
      Nonstop
      ORD 7:26 AM
      Knoxville - Chicago | Thu, Dec 24 | American Airlines
      $127 $152
      16% off
      16% off
      $152 $127
    • TYS 8:48 PM
      2h 12m
      Nonstop
      ORD 10:00 PM
      Knoxville - Chicago | Tue, Dec 29 | American Airlines
      $127 $152
      16% off
      16% off
      $152 $127
    • TYS 8:48 PM
      2h 12m
      Nonstop
      ORD 10:00 PM
      Knoxville - Chicago | Wed, Dec 23 | American Airlines
      $127
      16% off
      $152 $127
    • TYS 8:51 PM
      2h 9m
      Nonstop
      ORD 10:00 PM
      Knoxville - Chicago | Wed, Jan 6 | American Airlines
      $127
      16% off
      $152 $127
    • TYS 8:51 PM
      2h 9m
      Nonstop
      ORD 10:00 PM
      Knoxville - Chicago | Thu, Jan 7 | American Airlines
      $127
      16% off
      $152 $127
    • TYS 8:48 PM
      2h 12m
      Nonstop
      ORD 10:00 PM
      Knoxville - Chicago | Tue, Dec 22 | American Airlines
      $127
      16% off
      $152 $127
    • TYS 8:48 PM
      2h 12m
      Nonstop
      ORD 10:00 PM
      Knoxville - Chicago | Mon, Dec 28 | American Airlines
      $127
      16% off
      $152 $127
    • TYS 6:00 AM
      2h 26m
      Nonstop
      ORD 7:26 AM
      Knoxville - Chicago | Fri, Dec 25 | American Airlines
      $127
      16% off
      $152 $127
    • TYS 1:00 PM
      17h 25m
      1 stop
      CHI 2:00 PM
      Knoxville - Chicago | Wed, Oct 28 | Normal Airline
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    • Cheapest nonstop
      TYS 8:48 PM
      2h 12m
      Nonstop
      ORD 10:00 PM
      Knoxville - Chicago | Thu, Dec 31 | American Airlines
      $127 $268
      53% off
      53% off
      $268 $127
    • TYS 8:48 PM
      2h 12m
      Nonstop
      ORD 10:00 PM
      Knoxville - Chicago | Mon, Dec 21 | American Airlines
      $127 $268
      53% off
      53% off
      $268 $127
    • TYS 7:50 AM
      2h 20m
      Nonstop
      ORD 9:10 AM
      Knoxville - Chicago | Fri, Jan 8 | American Airlines
      $127 $268
      53% off
      53% off
      $268 $127
    • TYS 8:48 PM
      2h 12m
      Nonstop
      ORD 10:00 PM
      Knoxville - Chicago | Wed, Dec 23 | American Airlines
      $127
      53% off
      $268 $127
    • TYS 8:51 PM
      2h 9m
      Nonstop
      ORD 10:00 PM
      Knoxville - Chicago | Wed, Jan 6 | American Airlines
      $127
      53% off
      $268 $127
    • TYS 6:00 AM
      2h 26m
      Nonstop
      ORD 7:26 AM
      Knoxville - Chicago | Fri, Dec 25 | American Airlines
      $127
      53% off
      $268 $127
    • TYS 8:48 PM
      2h 12m
      Nonstop
      ORD 10:00 PM
      Knoxville - Chicago | Tue, Dec 29 | American Airlines
      $127
      53% off
      $268 $127
    • TYS 8:48 PM
      2h 12m
      Nonstop
      ORD 10:00 PM
      Knoxville - Chicago | Fri, Jan 1 | American Airlines
      $127
      53% off
      $268 $127
    • TYS 8:48 PM
      2h 12m
      Nonstop
      ORD 10:00 PM
      Knoxville - Chicago | Wed, Dec 30 | American Airlines
      $127
      53% off
      $268 $127
    • TYS 1:00 PM
      17h 25m
      1 stop
      CHI 2:00 PM
      Knoxville - Chicago | Wed, Oct 28 | Normal Airline
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    • Cheapest nonstop
      TYS 7:30 AM
      2h 9m
      Nonstop
      ORD 8:39 AM
      Knoxville - Chicago | Wed, Oct 28 | American Airlines
      $205 $410
      50% off
      50% off
      $410 $205
    • TYS 7:30 AM
      2h 9m
      Nonstop
      ORD 8:39 AM
      Knoxville - Chicago | Tue, Oct 27 | American Airlines
      $205 $410
      50% off
      50% off
      $410 $205
    • TYS 4:59 PM
      2h 12m
      Nonstop
      ORD 6:11 PM
      Knoxville - Chicago | Mon, Nov 2 | American Airlines
      $205 $410
      50% off
      50% off
      $410 $205
    • TYS 7:30 AM
      2h 9m
      Nonstop
      ORD 8:39 AM
      Knoxville - Chicago | Thu, Oct 29 | American Airlines
      $205
      50% off
      $410 $205
    • TYS 4:59 PM
      2h 12m
      Nonstop
      ORD 6:11 PM
      Knoxville - Chicago | Sun, Nov 1 | American Airlines
      $218
      47% off
      $410 $218
    • TYS 11:35 AM
      2h 2m
      Nonstop
      ORD 12:37 PM
      Knoxville - Chicago | Sat, Oct 31 | American Airlines
      $255
      38% off
      $410 $255
    • TYS 10:33 AM
      2h 6m
      Nonstop
      ORD 11:39 AM
      Knoxville - Chicago | Sun, Nov 1 | United Airlines
      $339
      17% off
      $410 $339
    • TYS 6:55 PM
      2h 8m
      Nonstop
      ORD 8:03 PM
      Knoxville - Chicago | Fri, Oct 30 | American Airlines
      $344
      16% off
      $410 $344
    • TYS 2:38 PM
      4h 9m
      1 stop
      ORD 5:47 PM
      Knoxville - Chicago | Sat, Oct 31 | Delta Air Lines
      $213
      48% off
      $410 $213
    • TYS 1:00 PM
      17h 25m
      1 stop
      CHI 2:00 PM
      Knoxville - Chicago | Wed, Oct 28 | Normal Airline
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    • TYS 1:55 PM
      2h
      Nonstop
      ORD 2:55 PM
      Knoxville - Chicago | Wed, Jan 6 | United Airlines
      $172 $550
      69% off
      69% off
      $550 $172
    • TYS 1:55 PM
      2h
      Nonstop
      ORD 2:55 PM
      Knoxville - Chicago | Thu, Jan 7 | United Airlines
      $172 $550
      69% off
      69% off
      $550 $172
    • TYS 1:55 PM
      2h
      Nonstop
      ORD 2:55 PM
      Knoxville - Chicago | Tue, Dec 15 | United Airlines
      $245 $550
      55% off
      55% off
      $550 $245
    • TYS 1:55 PM
      2h
      Nonstop
      ORD 2:55 PM
      Knoxville - Chicago | Fri, Jan 8 | United Airlines
      $261
      53% off
      $550 $261
    • TYS 1:55 PM
      2h
      Nonstop
      ORD 2:55 PM
      Knoxville - Chicago | Tue, Jan 5 | United Airlines
      $261
      53% off
      $550 $261
    • TYS 1:55 PM
      2h
      Nonstop
      ORD 2:55 PM
      Knoxville - Chicago | Wed, Dec 16 | United Airlines
      $262
      52% off
      $550 $262
    • TYS 1:55 PM
      2h
      Nonstop
      ORD 2:55 PM
      Knoxville - Chicago | Wed, Dec 9 | United Airlines
      $262
      52% off
      $550 $262
    • TYS 1:55 PM
      2h
      Nonstop
      ORD 2:55 PM
      Knoxville - Chicago | Tue, Dec 8 | United Airlines
      $305
      45% off
      $550 $305
    • TYS 1:55 PM
      2h
      Nonstop
      ORD 2:55 PM
      Knoxville - Chicago | Tue, Dec 1 | United Airlines
      $462
      16% off
      $550 $462
    • TYS 1:00 PM
      17h 25m
      1 stop
      CHI 2:00 PM
      Knoxville - Chicago | Wed, Oct 28 | Normal Airline
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Displayed flight fares from Knoxville to Chicago are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

Which airline offers the cheapest flights from Mcghee Tyson Airport to O'Hare Intl. Airport?

The cheapest airline flying from Mcghee Tyson Airport to O'Hare Intl. Airport is American Airlines (from $128) among 4 carriers operating this route. Based on Trip.com's latest 7-day flight data.

American Airlines
From $128
Delta Air Lines
From $131
United Airlines
From $168
Allegiant Air
From $216

Find more flights and airlines

What is the flight schedule from Mcghee Tyson Airport to O'Hare Intl. Airport?

Check the schedule for flights from Knoxville to Chicago and find the flight that best matches your travel plans.

Flight info.
Departure
Arrival
Weekly Schedule

  1. AA4229

    Mcghee Tyson Airport

    8:55 PM

    TYS

    2h 10m

    10:05 PM

    ORD

    S M T W T F S
    Search

  2. AA5408

    Mcghee Tyson Airport

    11:49 AM

    TYS

    2h 11m

    1:00 PM

    ORD

    S - - - - - S
    Search

  3. AA5340

    Mcghee Tyson Airport

    7:52 AM

    TYS

    2h 18m

    9:10 AM

    ORD

    S - - - - - -
    Search

  4. DL3015

    Mcghee Tyson Airport

    5:15 AM

    TYS

    1h 8m

    Nonstop

    6:23 AM

    ATL

    S M T W T F S
    Search

  5. DL1147

    Hartsfield–Jackson Atlanta International Airport

    8:05 AM

    ATL

    2h 20m

    Nonstop

    9:25 AM

    ORD

    S M T W T F S

  6. AA6018

    Mcghee Tyson Airport

    11:07 AM

    TYS

    1h 27m

    Nonstop

    12:34 PM

    CLT

    - - - - - - S
    Search

  7. AA1039

    Charlotte Douglas International Airport

    10:55 PM

    CLT

    2h 19m

    Nonstop

    12:14 AM

    ORD

    S - - - - - S

  8. DL1743

    Mcghee Tyson Airport

    12:00 PM

    TYS

    1h 5m

    Nonstop

    1:05 PM

    ATL

    S M T W T - S
    Search

  9. DL2738

    Hartsfield–Jackson Atlanta International Airport

    2:46 PM

    ATL

    2h 7m

    Nonstop

    3:53 PM

    ORD

    S M T W T - S

  10. DL5317

    Mcghee Tyson Airport

    7:08 AM

    TYS

    1h 17m

    Nonstop

    8:25 AM

    ATL

    S M T W T F S
    Search

  11. DL2894

    Hartsfield–Jackson Atlanta International Airport

    10:00 AM

    ATL

    2h 19m

    Nonstop

    11:19 AM

    ORD

    S M T W T F S
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About Mcghee Tyson Airport and O'Hare Intl. Airport

Learn about Mcghee Tyson Airport (TYS) and O'Hare Intl. Airport (ORD) — including location, terminals, transportation, and travel tips.

Flight distance 765.95 km
Cheapest one-way ticket price $127
Cheapest return ticket price $180

FAQs for Mcghee Tyson Airport to O'Hare Intl. Airport Flights

  • How long is the flight from Mcghee Tyson Airport to O'Hare Intl. Airport?

    Mcghee Tyson Airport to O'Hare Intl. Airport takes about 1 hour 24 minutes on average. Actual flight time may vary depending on route, weather and air traffic.
  • There are around 7 daily flights from Mcghee Tyson Airport (TYS) to O'Hare Intl. Airport (ORD).
  • The earliest flight from Mcghee Tyson Airport to O'Hare Intl. Airport departs at 06:00, and the last departs at 18:55, with about 9 flights per day. Flight times may change, so please check the latest departure and arrival times before you travel.
  • The route from Mcghee Tyson Airport (TYS) to O'Hare Intl. Airport (ORD) is quite popular. Without considering departure times or holidays, tickets cost around $280 in November, the most expensive month to book this route.
  • The earliest flight departs from Mcghee Tyson Airport (TYS) at 07:00 and arrives in O'Hare Intl. Airport (ORD) at 07:55.
  • The latest flight departs from Mcghee Tyson Airport (TYS) at 17:53 and arrives in O'Hare Intl. Airport (ORD) at 18:55.
    • The distance from O'Hare International Airport to downtown is about 25 km. It takes about 40 minutes by taxi.
    • The distance from Chicago Midway International Airport to downtown is about 14 km. It takes about 30 minutes by taxi.
  • The closest airport to O'Hare Intl. Airport (ORD) is Chicago Midway International Airport. The distance is around 25 km.
  • American Airlines is a very popular airline operating an average of 811 flights per month.
  • One-way flights from Mcghee Tyson Airport to O'Hare Intl. Airport currently start from $128, and round-trip fares start from $180. The current lowest fare is a American Airlines flight departing on Wed, Dec 23; prices may vary depending on availability.
  • Yes. American Airlines and United Airlines operate direct flights from Mcghee Tyson Airport to O'Hare Intl. Airport, with an average flight time of 1 hour 19 minutes, and around 55 weekly flights. Actual flight frequency may vary by season.
  • Based on Trip.com flight data for departures within the next 30 days with at most one stop, the average one-way price from Mcghee Tyson Airport to O'Hare Intl. Airport is $278. Prices may vary depending on the departure date, airline, and availability.
  • Mcghee Tyson Airport to O'Hare Intl. Airport operates around 55 weekly flights, mainly by American Airlines and United Airlines. Actual frequency may vary during holidays and seasonal schedule adjustments.
  • Enter Mcghee Tyson Airport and O'Hare Intl. Airport, select your departure date and number of passengers, then compare flights by price, flight duration, and baggage allowance. Once you've chosen a fare, review the change and refund rules, fill in passenger details, and pay to receive your booking confirmation.

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Note: Prices shown on this page are estimated lowest price and include all taxes and fees found in the last 24 hours.

Book with no extra fees

Prices displayed in this page are all-inclusive prices (incl. taxes, fuel surcharge, civil aviation development fund, etc) with all fees confirmed before payment. Fees for luggage, meals, WLAN, or other additional services are also included as shown in the flight cards.

Real-time pricing updates

Prices, availability, and travel information on this page were updated within last 24 hours—even in real-time. The more popular the route, the more precise the data.

Change & Cancellation Policy

Trip.com displays flight cancellation and change policies for each flight ticket during the booking process, including fees and applicable conditions. Please check the following scenarios:
Voluntary cancellation/change:
To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy.
Cancellation/change due to a flight schedule change:
If the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.