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Flights from Appleton to Knoxville

Find cheap airlines flights from Appleton to Knoxville

You can choose from 1 airlines that fly from Appleton to Knoxville, including Delta Air Lines, United Airlines has lowest fares on this route.
Delta Air Lines logo Delta Air Lines
Airlines are determined based on actual purchased flight tickets from Appleton to Knoxville according to previous 12 months data from Trip.com.

Find flight deals from Appleton to Knoxville for the next 3 months. Book one way flights from $186 or round trip flights from $363.

      • ATW 5:30 AM
        4h 47m
        1 stop
        TYS 11:17 AM
        Appleton - Knoxville | Mon, May 4 | Delta Air Lines
        TYS 7:51 AM
        3h 37m
        1 stop
        ATW 10:28 AM
        Knoxville - Appleton | Fri, May 8 | Delta Air Lines
        $363 $529
        31% off
        31% off
        $529 $363
      • ATW 4:20 PM
        5h 39m
        1 stop
        TYS 10:59 PM
        Appleton - Knoxville | Sun, Apr 26 | Delta Air Lines
        TYS 6:15 AM
        6h 7m
        1 stop
        ATW 11:22 AM
        Knoxville - Appleton | Thu, Apr 30 | Delta Air Lines
        $382 $529
        28% off
        28% off
        $529 $382
      • ATW 3:46 PM
        6h 22m
        1 stop
        TYS 11:08 PM
        Appleton - Knoxville | Thu, Apr 23 | United Airlines
        TYS 10:49 AM
        5h 22m
        1 stop
        ATW 3:11 PM
        Knoxville - Appleton | Sun, Apr 26 | United Airlines
        $400 $529
        24% off
        24% off
        $529 $400
      • ATW 3:46 PM
        5h 48m
        1 stop
        TYS 10:34 PM
        Appleton - Knoxville | Sun, Apr 26 | United Airlines
        TYS 10:49 AM
        5h 22m
        1 stop
        ATW 3:11 PM
        Knoxville - Appleton | Thu, Apr 30 | United Airlines
        $408
        23% off
        $529 $408
      • ATW 3:46 PM
        5h 43m
        1 stop
        TYS 10:29 PM
        Appleton - Knoxville | Tue, Apr 21 | United Airlines
        TYS 7:00 AM
        5h 48m
        1 stop
        ATW 11:48 AM
        Knoxville - Appleton | Fri, Apr 24 | United Airlines
        $410
        22% off
        $529 $410
      • ATW 4:20 PM
        5h 39m
        1 stop
        TYS 10:59 PM
        Appleton - Knoxville | Tue, Apr 21 | Delta Air Lines
        TYS 5:54 PM
        4h 43m
        1 stop
        ATW 9:37 PM
        Knoxville - Appleton | Thu, Apr 23 | Delta Air Lines
        $412
        22% off
        $529 $412
      • ATW 9:50 AM
        6h 9m
        1 stop
        TYS 4:59 PM
        Appleton - Knoxville | Mon, May 4 | United Airlines
        TYS 7:00 AM
        5h 54m
        1 stop
        ATW 11:54 AM
        Knoxville - Appleton | Fri, May 8 | United Airlines
        $431
        19% off
        $529 $431
      • ATW 3:46 PM
        5h 48m
        1 stop
        TYS 10:34 PM
        Appleton - Knoxville | Wed, Apr 22 | United Airlines
        TYS 7:00 AM
        5h 58m
        1 stop
        ATW 11:58 AM
        Knoxville - Appleton | Sun, Apr 26 | United Airlines
        $434
        18% off
        $529 $434
      • ATW 5:30 AM
        4h 47m
        1 stop
        TYS 11:17 AM
        Appleton - Knoxville | Sat, Apr 18 | Delta Air Lines
        TYS 4:38 PM
        5h 59m
        1 stop
        ATW 9:37 PM
        Knoxville - Appleton | Sat, Apr 18 | Delta Air Lines
        $438
        17% off
        $529 $438
      • ATW 2:40 PM
        5h 16m
        1 stop
        TYS 8:56 PM
        Appleton - Knoxville | Sun, Jun 7 | United Airlines
        TYS 6:30 AM
        4h 33m
        1 stop
        ATW 10:03 AM
        Knoxville - Appleton | Fri, Jun 12 | United Airlines
        $444
        16% off
        $529 $444
      • ATW 1:00 PM
        17h 25m
        1 stop
        TYS Invalid Date
        Appleton - Knoxville | Wed, Apr 15 | Normal Airline
        TYS 3:00 PM
        6h
        Nonstop
        ATW 4:00 PM
        Knoxville - Appleton | Fri, Apr 17 | Normal Airline
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      • ATW 2:54 PM
        7h 9m
        1 stop
        TYS 11:03 PM
        Appleton - Knoxville | Thu, Apr 16 | United Airlines
        $186 $334
        44% off
        44% off
        $334 $186
      • ATW 5:30 AM
        6h 40m
        1 stop
        TYS 1:10 PM
        Appleton - Knoxville | Tue, Jun 2 | Delta Air Lines
        $197 $334
        41% off
        41% off
        $334 $197
      • ATW 7:00 AM
        6h 20m
        1 stop
        TYS 2:20 PM
        Appleton - Knoxville | Sat, May 9 | Delta Air Lines
        $201 $334
        40% off
        40% off
        $334 $201
      • ATW 5:30 AM
        6h 40m
        1 stop
        TYS 1:10 PM
        Appleton - Knoxville | Wed, May 27 | Delta Air Lines
        $213
        36% off
        $334 $213
      • ATW 3:47 PM
        4h 9m
        1 stop
        TYS 8:56 PM
        Appleton - Knoxville | Wed, May 27 | United Airlines
        $222
        34% off
        $334 $222
      • ATW 6:00 AM
        6h 2m
        1 stop
        TYS 1:02 PM
        Appleton - Knoxville | Wed, May 27 | American Airlines
        $228
        32% off
        $334 $228
      • ATW 1:20 PM
        7h 1m
        1 stop
        TYS 9:21 PM
        Appleton - Knoxville | Sat, May 9 | American Airlines
        $280
        16% off
        $334 $280
      • ATW 1:00 PM
        17h 25m
        1 stop
        TYS Invalid Date
        Appleton - Knoxville | Wed, Apr 15 | Normal Airline
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        Find more flights

Displayed flight fares from Appleton to Knoxville are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

Flight Info | Appleton to Knoxville

The distance between Appleton and Knoxville is approximately 1,015.56 km. Based on Trip.com's data travel demand peaks in December. The off-season for travel is October.

Cheapest one-way flight price$186
Cheapest round-trip ticket price$363
Off-season for travelOctober
Peak season for travelDecember
Flight distance1,015.56 km
Popular airlineDelta Air Lines
Flight statistics for the Appleton–Knoxville route are based on aggregated booking data from Trip.com over the past 12 months.

Frequently Asked Questions

  • What are the cheapest flights from Appleton to Knoxville (ATW-TYS)?

    Based on Trip.com data, United Airlines offers one-way fares as low as $186 on Cheapest nonstop routes (e.g. ATW to TYS on Thu, Apr 16), while Delta Air Lines offers Cheapest nonstop round-trips from $363 departing on Mon, May 4 and returning on Fri, May 8.
  • At the moment, several airlines serve connecting flights from Appleton to Knoxville, including: Delta Air Lines Selected airlines are based on historical data collected from flight bookings made by users on Trip.com within the last 90 days.
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Appleton to Knoxville is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • To find best deals on flights from Appleton to Knoxville, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Thu, Apr 16, with one-way flights priced at just $186.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is United Airlines.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Knoxville travel is around December.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Appleton to Knoxville is October, when demand for travel is lower.
  • After crunching the numbers on our April flight calendar, it's currently cheapest to fly from Appleton to Knoxville on April 25, 2026 with Delta Air Lines, with prices starting at $382.
  • You can land at any one of the following hubs in Knoxville, with Appleton International Airport to Mcghee Tyson Airport (ATW-TYS) is by far the most common option on this route: Mcghee Tyson Airport (TYS).
  • The time difference between Knoxville and Appleton is 1h.
  • Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

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Note: Prices shown on this page are estimated lowest price and include all taxes and fees found in the last 24 hours.

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Prices displayed in this page are all-inclusive prices (incl. taxes, fuel surcharge, civil aviation development fund, etc) with all fees confirmed before payment. Fees for luggage, meals, WLAN, or other additional services are also included as shown in the flight cards.

Real-time pricing updates

Prices, availability, and travel information on this page were updated within last 24 hours—even in real-time. The more popular the route, the more precise the data.

Change & Cancellation Policy

Trip.com displays flight cancellation and change policies for each flight ticket during the booking process, including fees and applicable conditions. Please check the following scenarios:
Voluntary cancellation/change:
To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy.
Cancellation/change due to a flight schedule change:
If the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.