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Flights from Boston to St. Louis

Find cheap airlines flights from Boston to St. Louis

Choose from 1 carriers that fly from Boston to St. Louis, including American Airlines, Enjoy the cheapest tickets on this route with American Airlines.
American Airlines logo American Airlines

Book direct flights from Boston to St. Louis: One way flights from $182, round trip flights from $305. Find flight deals for the next 3 months below.

      • Cheapest nonstop
        BOS 7:00 AM
        3h 23m
        Nonstop
        STL 9:23 AM
        Boston - St. Louis | Thu, Nov 27 | American Airlines
        STL 11:50 AM
        2h 40m
        Nonstop
        BOS 3:30 PM
        St. Louis - Boston | Wed, Dec 3 | American Airlines
        $305 $423
        28% OFF
        28% OFF
        $423 $305
      • BOS 5:45 AM
        9h 7m
        1 stop
        STL 1:52 PM
        Boston - St. Louis | Thu, Dec 4 | Spirit Airlines
        STL 8:38 AM
        8h 33m
        1 stop
        BOS 6:11 PM
        St. Louis - Boston | Mon, Dec 8 | American Airlines
        $259 $423
        39% OFF
        39% OFF
        $423 $259
      • BOS 11:19 AM
        7h 37m
        1 stop
        STL 5:56 PM
        Boston - St. Louis | Fri, Dec 5 | Frontier Airlines
        STL 1:59 PM
        8h 41m
        1 stop
        BOS 11:40 PM
        St. Louis - Boston | Mon, Dec 8 | American Airlines
        $281 $423
        34% OFF
        34% OFF
        $423 $281
      • BOS 9:15 AM
        5h 41m
        1 stop
        STL 1:56 PM
        Boston - St. Louis | Thu, Nov 27 | Delta Air Lines
        STL 6:39 AM
        4h 20m
        1 stop
        BOS 11:59 AM
        St. Louis - Boston | Wed, Dec 3 | Delta Air Lines
        $308
        27% OFF
        $423 $308
      • BOS 8:50 AM
        3h 24m
        Nonstop
        STL 11:14 AM
        Boston - St. Louis | Thu, Dec 4 | American Airlines
        STL 8:38 AM
        8h 33m
        1 stop
        BOS 6:11 PM
        St. Louis - Boston | Mon, Dec 8 | American Airlines
        $310
        27% OFF
        $423 $310
      • BOS 6:00 AM
        7h 40m
        1 stop
        STL 12:40 PM
        Boston - St. Louis | Thu, Dec 4 | Delta Air Lines
        STL 8:38 AM
        8h 33m
        1 stop
        BOS 6:11 PM
        St. Louis - Boston | Mon, Dec 8 | American Airlines
        $314
        26% OFF
        $423 $314
      • BOS 9:40 AM
        5h 43m
        1 stop
        STL 2:23 PM
        Boston - St. Louis | Thu, Dec 4 | United Airlines
        STL 8:38 AM
        8h 33m
        1 stop
        BOS 6:11 PM
        St. Louis - Boston | Mon, Dec 8 | American Airlines
        $326
        23% OFF
        $423 $326
      • BOS 6:00 AM
        7h 28m
        1 stop
        STL 12:28 PM
        Boston - St. Louis | Thu, Nov 27 | United Airlines
        STL 2:07 PM
        6h 19m
        1 stop
        BOS 9:26 PM
        St. Louis - Boston | Wed, Dec 3 | Delta Air Lines
        $343
        19% OFF
        $423 $343
      • BOS 6:00 AM
        9h 50m
        1 stop
        STL 2:50 PM
        Boston - St. Louis | Mon, Dec 15 | American Airlines
        STL 7:05 AM
        7h 36m
        1 stop
        BOS 3:41 PM
        St. Louis - Boston | Fri, Dec 19 | Delta Air Lines
        $352
        17% OFF
        $423 $352
      • BOS 4:46 PM
        5h 1m
        1 stop
        STL 8:47 PM
        Boston - St. Louis | Mon, Dec 15 | Delta Air Lines
        STL 9:30 AM
        5h 11m
        1 stop
        BOS 3:41 PM
        St. Louis - Boston | Fri, Dec 19 | Delta Air Lines
        $360
        15% OFF
        $423 $360
      • BOS 1:00 PM
        17h 25m
        1 stop
        STL Invalid Date
        Boston - St. Louis | Tue, Nov 18 | Normal Airline
        STL 3:00 PM
        6h
        Nonstop
        BOS 4:00 PM
        St. Louis - Boston | Thu, Nov 20 | Normal Airline
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Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Flight Info | Boston to St. Louis

The distance between Boston and St. Louis is about 1,670.94 km. It takes around 3 hours 13 minutes on average to fly from Boston to St. Louis. The most popular month to St. Louis is July. The off-season for travel is August.

Cheapest one-way flight price$61
Cheapest round-trip ticket price$259
Off-season for travelAugust
Peak season for travelJuly
Flight distance1,670.94 km
Average flight time3 hours 13 minutes
Popular airlineAmerican Airlines

When is the cheapest time to fly from Boston to St. Louis?

The cheapest time for Boston to St. Louis flights: Jan 11 to Jan 18 — one way flight prices from $60.

Cheapest flights
From price
Search
  • 1623
  • 2330

  • Dec

    307
  • 714
  • 1421
  • 2128

  • Jan

    284
  • 411
  • 1118
  • 1825

  • Feb

    251
  • 18
Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

  • Which airlines offer direct flights from Boston to St. Louis?

    At the moment, you can catch a nonstop flight from Boston to St. Louis with the following airlines, including: American Airlines Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.
  • It takes around 3 hours 13 minutes to fly from Boston (BOS) to St. Louis (STL).
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Boston to St. Louis is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • Based on Trip.com data in the past 4 weeks, there is 12 flight per week flying from Boston to St. Louis. You can check the weekly schedule for popular airlines on this route below: American Airlines: S/M/T/W/T/F/S -- AA3520 (12:45)
  • The cheapest months to fly from Boston to St. Louis is August, when demand for travel is lower.
  • After crunching the numbers on our November flight calendar, it's currently cheapest to fly from Boston to St. Louis on November 20, 2025 with American Airlines, with prices starting at $201.
  • You can land at any one of the following hubs in St. Louis, with Logan International Airport to St. Louis Lambert International Airport (BOS-STL) is by far the most common option on this route: St. Louis Lambert International Airport (STL) St. Louis Downtown Airport (CPS).
  • The time difference between St. Louis and Boston is 1h.
  • Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

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