Cheap Flights from Buffalo to San Diego from $108

Frequently Asked Questions

• What are the cheapest flights from Buffalo to San Diego (BUF-SAN)?

  Based on Trip.com data, American Airlines offers one-way fares as low as $108 on Cheapest nonstop routes (e.g. BUF to SAN on Fri, Nov 6), while Delta Air Lines offers Cheapest nonstop round-trips from $313 departing on Fri, Nov 13 and returning on Thu, Nov 19.

• Which airlines offer flights from Buffalo to San Diego?

  At the moment, several airlines serve connecting flights from Buffalo to San Diego, including: American Airlines Selected airlines are based on historical data collected from flight bookings made by users on Trip.com within the last 90 days.

• When is the best time to book flights from Buffalo to San Diego?

  By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Buffalo to San Diego is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.

• How can I find the best deals on flights from Buffalo to San Diego?

  To find best deals on flights from Buffalo to San Diego, you can use various tools on Trip.com:
  · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Fri, Nov 6, with one-way flights priced at just $108.
  · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is American Airlines.
  · Set up price alerts to easily monitor ticket prices without having to check every day.
  · Check Trip.com flight deals and promo codes frequently.
  · Avoid peak season unless you book very early. It seems the peak season for San Diego travel is around July.
  · Get exclusive promo codes for Trip.com app users.

• When are flight tickets from Buffalo (BUF) to San Diego (SAN) the cheapest?

  The cheapest months to fly from Buffalo to San Diego is October, when demand for travel is lower.

• Which upcoming date is cheapest to fly from Buffalo to San Diego on?

  After crunching the numbers on our October flight calendar, it's currently cheapest to fly from Buffalo to San Diego on October 23, 2026 with American Airlines, with prices starting at $246.

• Which airports can I fly into San Diego from Buffalo?

  You can arrive at any of the following airports in San Diego: San Diego International Airport (SAN), McClellan-Palomar Airport (CLD), and Marine Corps Air Station Miramar (NKX). Flights from Buffalo Niagara International Airport to San Diego International Airport (BUF-SAN) are by far the most popular option for this route.

• Is there any time difference between Buffalo and San Diego?

  The time difference between San Diego and Buffalo is 3h.

• How do I change or cancel my ticket from Buffalo to San Diego?

  Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

• What is the average cost of a one-way flight from Buffalo to San Diego?

  Based on Trip.com data for flights departing in the next 30 days, the average one-way fare from Buffalo to San Diego is $303. Fares vary by travel date, airline and availability.

• What is the average cost of a round-trip flight from Buffalo to San Diego?

  Based on Trip.com data for travel in the next 30 days, the average round-trip fare from Buffalo to San Diego is $1,030. The final price depends on the outbound and return dates, airline and fare conditions.

• How do I book flights from Buffalo to San Diego on Trip.com?

  Enter Buffalo and San Diego, choose your travel dates and passengers, then compare flights by price, duration and baggage. Select a fare, review the change and cancellation rules, enter traveler details and complete payment to receive your confirmation.