$163 Cheap Flights from Des Moines to Greenville (DSM to GSP)

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Cheap flight deals from Des Moines to Greenville Starting at $163

For as little as $163, you can take your next adventure to Greenville without breaking the bank. Choose between one-way and return tickets from Des Moines below.

One way
Round-trip

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

When is the cheapest time to fly from Des Moines to Greenville?

These price trend charts carefully monitor and predict how flight prices from Des Moines to Greenville will change. Keep a close eye on them to understand when the best time to buy your tickets is.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Find cheap airlines flights from Des Moines to Greenville

We have a range of prices from different airlines providing flights from Des Moines to Greenville. Check below for the journey which best suits your travel needs.

Delta Air Lines

From $163

United Airlines

From $196

American Airlines

From $196

Find more flights and airlines

Alternative Cheap Routes from Des Moines to Greenville

Did you know that you can save money and time on an alternative route from Des Moines to Greenville? Check out some of the different available routes below.

Cheapest
DSM
07:05 am
8h 39m
1 transfer
GSP
04:44 pm
Des Moines International Airport - Greenville-Spartanburg International Airport
Thu, Jan 16Delta Air Lines
$163
DSM
07:05 am
8h 39m
1 transfer
GSP
04:44 pm
Des Moines International Airport - Greenville-Spartanburg International Airport
Thu, Jan 16Delta Air Lines
$163
Find More Flights

Frequently Asked Questions

When are flight tickets from Des Moines (DSM) to Greenville (GSP) the cheapest?
Airlines adjust prices for flights from Des Moines to Greenville based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.
How much do flights from Des Moines (DSM) to Greenville (GSP) cost?
According to Trip.com's data, the lowest price is around $466.
What is the transportation method from the main airport to downtown in Greenville?
- The distance from Greenville-Spartanburg International Airport to downtown is about 16 km. It takes about 30 minutes by taxi.

How to find a cheap flight from Des Moines to Greenville

Understanding the common pitfalls when booking your flight tickets can help you save massively when it comes time to fly. We’ve listed our six essential steps to keep in mind when you’re booking flight tickets to help you find the best price.

Book Early

Once prices are gone, they're gone. Lock in deals while you can!

Compare Flight Prices

Compare prices on travel agency and airline websites.

Look Out for Deals

Check airline and travel agency websites for latest flight deals

Check One-way Fares

Buying two cheap one-way flights can sometimes be a better deal than a round-trip.

Try Different Dates

Flying during the week, early in the morning, or late at night can help save money.

Use the Trip.com App

Save up to £10 per person when booking your flights on Trip.com

Flight Info | Des Moines to Greenville

Cheapest nonstop flight price	$163
Off-season for travel	November
Peak season for travel	March
Flight distance	1,232.43 km
Popular airline	American Airlines