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Flights from Des Moines to Guadalajara Starting at $291

We've found these cheap flights for you. You can book one-way or round-trip flight tickets.

  • One way
  • Round-trip

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

When is the cheapest time to fly from Des Moines to Guadalajara?

We monitor flight fares to help you find the best deals effortlessly

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.
Find cheap airlines flights from Des Moines to Guadalajara

Compare prices, find the option that best suits your travel needs, and enjoy a comfortable journey with a trusted airline.

Frontier Airlines
From $271
American Airlines
From $281
Delta Air Lines
From $291
Aeromexico
From $306
United Airlines
From $327
ANA airlines

Find more flights and airlines

Alternative Cheap Routes from Des Moines to Guadalajara

Searching for potential routes that might be cheaper and faster? Check out these alternative flights from Des Moines to Guadalajara.

  • Cheapest
    Frontier Airlines
    DSM
    12:01
    26h 43m
    2 transfer
    GDL
    13:44
    Des Moines International Airport - Miguel Hidalgo y Costilla International Airport
    Wed, Apr 3Frontier Airlines
    $271
  • Frontier Airlines
    DSM
    12:01
    26h 43m
    2 transfer
    GDL
    13:44
    Des Moines International Airport - Miguel Hidalgo y Costilla International Airport
    Wed, Apr 3Frontier Airlines
    $271
    Find More Flights

Frequently Asked Questions

  • When are flight tickets from Des Moines (DSM) to Guadalajara (GDL) the cheapest?

    Airlines adjust prices for flights from Des Moines to Guadalajara based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.
  • How much do flights from Des Moines (DSM) to Guadalajara (GDL) cost?

    According to Trip.com's data, the lowest price is around $569.
  • What is the transportation method from the main airport to downtown in Guadalajara?

    • The distance from Miguel Hidalgo y Costilla International Airport to downtown is about 15km. It takes about 30 minutes by taxi.

Travel Info | Des Moines to Guadalajara

Cheapest nonstop flight price

$291

Off-season for travel

January

Peak season for travel

October