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Flights from Des Moines to Los Angeles

Book direct flights from Des Moines to Los Angeles: One way flights from $148, round trip flights from $440. Find flight deals for the next 3 months below.

      • Cheapest nonstop
        DSM 6:48 PM
        3h 54m
        Nonstop
        LAX 8:42 PM
        Des Moines - Los Angeles | Fri, Aug 14 | American Airlines
        LAX 12:37 PM
        3h 40m
        Nonstop
        DSM 6:17 PM
        Los Angeles - Des Moines | Wed, Aug 19 | American Airlines
        $440 $502
        12% off
        12% off
        $502 $440
      • DSM 6:48 PM
        3h 54m
        Nonstop
        LAX 8:42 PM
        Des Moines - Los Angeles | Sat, Aug 29 | American Airlines
        LAX 12:37 PM
        3h 40m
        Nonstop
        DSM 6:17 PM
        Los Angeles - Des Moines | Tue, Sep 1 | American Airlines
        $441 $502
        12% off
        12% off
        $502 $441
      • DSM 2:45 PM
        8h 18m
        1 stop
        LAX 9:03 PM
        Des Moines - Los Angeles | Sun, Aug 16 | Delta Air Lines
        LAX 6:20 AM
        5h 44m
        1 stop
        DSM 2:04 PM
        Los Angeles - Des Moines | Fri, Aug 21 | Delta Air Lines
        $327 $502
        35% off
        35% off
        $502 $327
      • DSM 11:28 AM
        9h 49m
        1 stop
        LAX 7:17 PM
        Des Moines - Los Angeles | Tue, Sep 8 | Delta Air Lines
        LAX 10:40 PM
        8h 53m
        1 stop
        DSM 9:33 AM
        Los Angeles - Des Moines | Thu, Sep 10 | Delta Air Lines
        $342
        32% off
        $502 $342
      • DSM 6:00 AM
        10h 34m
        1 stop
        LAX 2:34 PM
        Des Moines - Los Angeles | Mon, Aug 31 | Delta Air Lines
        LAX 11:59 PM
        8h 19m
        1 stop
        DSM 10:18 AM
        Los Angeles - Des Moines | Thu, Sep 3 | Delta Air Lines
        $372
        26% off
        $502 $372
      • DSM 1:35 PM
        5h 54m
        1 stop
        LAX 5:29 PM
        Des Moines - Los Angeles | Mon, Aug 31 | United Airlines
        LAX 8:45 AM
        5h 34m
        1 stop
        DSM 4:19 PM
        Los Angeles - Des Moines | Thu, Sep 3 | United Airlines
        $376
        25% off
        $502 $376
      • DSM 2:45 PM
        8h 18m
        1 stop
        LAX 9:03 PM
        Des Moines - Los Angeles | Mon, Sep 7 | Delta Air Lines
        LAX 10:40 PM
        9h 3m
        1 stop
        DSM 9:43 AM
        Los Angeles - Des Moines | Wed, Sep 9 | Delta Air Lines
        $378
        25% off
        $502 $378
      • DSM 5:45 AM
        5h 47m
        1 stop
        LAX 9:32 AM
        Des Moines - Los Angeles | Sun, Aug 16 | United Airlines
        LAX 5:00 AM
        5h 32m
        1 stop
        DSM 12:32 PM
        Los Angeles - Des Moines | Fri, Aug 21 | United Airlines
        $399
        21% off
        $502 $399
      • DSM 6:48 PM
        3h 54m
        Nonstop
        LAX 8:42 PM
        Des Moines - Los Angeles | Sun, Aug 16 | American Airlines
        LAX 12:41 AM
        7h 15m
        1 stop
        DSM 9:56 AM
        Los Angeles - Des Moines | Fri, Aug 21 | American Airlines
        $408
        19% off
        $502 $408
      • DSM 6:50 PM
        3h 52m
        Nonstop
        LAX 8:42 PM
        Des Moines - Los Angeles | Fri, Jul 24 | American Airlines
        LAX 1:10 AM
        6h 1m
        1 stop
        DSM 9:11 AM
        Los Angeles - Des Moines | Thu, Jul 30 | American Airlines
        $414
        18% off
        $502 $414
      • DSM 1:00 PM
        17h 25m
        1 stop
        LAX 2:00 PM
        Des Moines - Los Angeles | Wed, Jul 22 | Normal Airline
        LAX 3:00 PM
        6h
        Nonstop
        DSM 4:00 PM
        Los Angeles - Des Moines | Fri, Jul 24 | Normal Airline
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      • Cheapest nonstop
        DSM 6:57 PM
        3h 56m
        Nonstop
        LAX 8:53 PM
        Des Moines - Los Angeles | Sun, Sep 13 | American Airlines
        $148 $302
        51% off
        51% off
        $302 $148
      • DSM 6:07 PM
        3h 56m
        Nonstop
        LAX 8:03 PM
        Des Moines - Los Angeles | Thu, Sep 17 | American Airlines
        $265 $302
        12% off
        12% off
        $302 $265
      • DSM 9:21 PM
        19h 44m
        1 stop
        LAX 3:05 PM
        Des Moines - Los Angeles | Sun, Aug 9 | Allegiant Air
        $128 $302
        57% off
        57% off
        $302 $128
      • DSM 10:06 PM
        13h 23m
        1 stop
        LAX 9:29 AM
        Des Moines - Los Angeles | Wed, Aug 19 | Allegiant Air
        $128
        57% off
        $302 $128
      • DSM 1:00 PM
        17h 25m
        1 stop
        LAX 2:00 PM
        Des Moines - Los Angeles | Wed, Jul 22 | Normal Airline
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Find cheap airlines flights from Des Moines to Los Angeles

You can choose from 1 airlines that fly from Des Moines to Los Angeles, including American Airlines, American Airlines has lowest fares on this route.
American Airlines logo American Airlines
Airlines are determined based on actual purchased flight tickets from Des Moines to Los Angeles according to previous 12 months data from Trip.com.

Flight Info | Des Moines to Los Angeles

The distance between Des Moines and Los Angeles is approximately 2,324.07 km. It takes around 3 hours 52 minutes on average to fly from Des Moines to Los Angeles. Based on Trip.com's data travel demand peaks in January. The off-season for travel is October.

Cheapest one-way flight price$128
Cheapest round-trip ticket price$327
Off-season for travelOctober
Peak season for travelJanuary
Flight distance2,324.07 km
Average flight time3 hours 52 minutes
Popular airlineAmerican Airlines
Flight statistics for the Des Moines–Los Angeles route are based on aggregated booking data from Trip.com over the past 12 months.

Frequently Asked Questions

  • What are the cheapest flights from Des Moines to Los Angeles (DSM-LAX)?

    Based on Trip.com data, Allegiant Air offers one-way fares as low as $128 on Cheapest nonstop routes (e.g. DSM to LAX on Sun, Aug 9), while Delta Air Lines offers Cheapest nonstop round-trips from $327 departing on Sun, Aug 16 and returning on Fri, Aug 21.
  • At the moment, you can catch a nonstop flight from Des Moines to Los Angeles with the following airlines, including: American Airlines Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.
  • It takes around 3 hours 52 minutes to fly from Des Moines (DSM) to Los Angeles (LAX).
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Des Moines to Los Angeles is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • Based on Trip.com data in the past 4 weeks, there is 6 flight per week flying from Des Moines to Los Angeles. You can check the weekly schedule for popular airlines on this route below: American Airlines: S/M/T/W/T/F/S -- AA4971 (20:01)
  • To find best deals on flights from Des Moines to Los Angeles, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Sun, Aug 9, with one-way flights priced at just $128.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is American Airlines.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Los Angeles travel is around January.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Des Moines to Los Angeles is October, when demand for travel is lower.
  • After crunching the numbers on our July flight calendar, it's currently cheapest to fly from Des Moines to Los Angeles on July 20, 2026 with Allegiant Air, with prices starting at $90.
  • You can land at any one of the following hubs in Los Angeles, with Des Moines International Airport to Los Angeles International Airport (DSM-LAX) is by far the most common option on this route: Los Angeles International Airport (LAX) Ontario International Airport (ONT) Van Nuys Airport (VNY).
  • The time difference between Los Angeles and Des Moines is 2h.
  • Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

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Note: Prices shown on this page are estimated lowest price and include all taxes and fees found in the last 24 hours.

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Prices displayed in this page are all-inclusive prices (incl. taxes, fuel surcharge, civil aviation development fund, etc) with all fees confirmed before payment. Fees for luggage, meals, WLAN, or other additional services are also included as shown in the flight cards.

Real-time pricing updates

Prices, availability, and travel information on this page were updated within last 24 hours—even in real-time. The more popular the route, the more precise the data.

Change & Cancellation Policy

Trip.com displays flight cancellation and change policies for each flight ticket during the booking process, including fees and applicable conditions. Please check the following scenarios:
Voluntary cancellation/change:
To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy.
Cancellation/change due to a flight schedule change:
If the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.