Cheap flight deals from Des Moines to Palermo Starting at $597

We've found these cheap flights for you. You can book one-way or round-trip flight tickets.

Round-trip
One way

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

When is the cheapest time to fly from Des Moines to Palermo?

We monitor flight fares to help you find the best deals effortlessly

Cheapest flights

From price

9 16
16 23
23 30
Apr

30 6
6 13
13 20
20 27
May

27 4
4 11
11 18
18 25
Jun

25 1

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

When are flight tickets from Des Moines (DSM) to Palermo (PMO) the cheapest?

Airlines adjust prices for flights from Des Moines to Palermo based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.
How much do flights from Des Moines (DSM) to Palermo (PMO) cost?

According to Trip.com's data, the lowest price is around $1,510.
What is the transportation method from the main airport to downtown in Palermo?
- The distance from Falcone-Borsellino International Airport to downtown is about 23 km. It takes about 40 minutes by taxi.

How to find a cheap flight from Des Moines to Palermo

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Des Moines to Palermo. Book your flights at the right time and save more.

Be flexible with your travel dates to get the cheapest Des Moines to Palermo ticket.

Tap "Date" on flight search bar to get the calender for Des Moines to Palermo airfare over next 6 months in 2025.

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Book early or wait unitl the last minute to fine the best fares.

It's always better to book early! Airlines typically release their lowest fares about a year before departure, so check as soon as flights become available. If you miss that window, you may still find great deals closer to your travel date.

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