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Flights from Guayaquil to Medellin

Find cheap airlines flights from Guayaquil to Medellin

You can choose from 1 airlines that fly from Guayaquil to Medellin, including avianca, avianca has lowest fares on this route.
avianca logo avianca
Airlines are determined based on actual purchased flight tickets from Guayaquil to Medellin according to previous 12 months data from Trip.com.

Book direct flights from Guayaquil to Medellin: One way flights from $184, round trip flights from $349. Find flight deals for the next 3 months below.

      • Cheapest nonstop
        GYE 1:40 PM
        1h 50m
        Nonstop
        MDE 3:30 PM
        Guayaquil - Medellin | Mon, Jun 8 | avianca
        MDE 4:50 PM
        2h
        Nonstop
        GYE 6:50 PM
        Medellin - Guayaquil | Mon, Jun 15 | avianca
        $349 $509
        31% off
        31% off
        $509 $349
      • GYE 2:05 PM
        1h 50m
        Nonstop
        MDE 3:55 PM
        Guayaquil - Medellin | Wed, Jun 10 | avianca
        MDE 4:50 PM
        2h
        Nonstop
        GYE 6:50 PM
        Medellin - Guayaquil | Wed, Jun 17 | avianca
        $370 $509
        27% off
        27% off
        $509 $370
      • GYE 2:05 PM
        1h 50m
        Nonstop
        MDE 3:55 PM
        Guayaquil - Medellin | Wed, Jun 24 | avianca
        MDE 4:50 PM
        2h
        Nonstop
        GYE 6:50 PM
        Medellin - Guayaquil | Mon, Jun 29 | avianca
        $370 $509
        27% off
        27% off
        $509 $370
      • GYE 2:05 PM
        1h 50m
        Nonstop
        MDE 3:55 PM
        Guayaquil - Medellin | Wed, Jul 8 | avianca
        MDE 4:50 PM
        2h
        Nonstop
        GYE 6:50 PM
        Medellin - Guayaquil | Fri, Jul 10 | avianca
        $371
        27% off
        $509 $371
      • GYE 9:10 AM
        9h
        1 stop
        MDE 6:10 PM
        Guayaquil - Medellin | Tue, Jul 7 | avianca
        MDE 4:50 PM
        2h
        Nonstop
        GYE 6:50 PM
        Medellin - Guayaquil | Mon, Jul 13 | avianca
        $358
        30% off
        $509 $358
      • GYE 5:59 AM
        8h 46m
        1 stop
        MDE 2:45 PM
        Guayaquil - Medellin | Wed, Jul 29 | Copa Airlines
        MDE 6:25 AM
        17h 13m
        1 stop
        GYE 11:38 PM
        Medellin - Guayaquil | Sun, Aug 2 | Copa Airlines
        $361
        28% off
        $509 $361
      • GYE 2:05 PM
        1h 50m
        Nonstop
        MDE 3:55 PM
        Guayaquil - Medellin | Wed, Jul 15 | avianca
        MDE 4:50 AM
        12h 45m
        1 stop
        GYE 5:35 PM
        Medellin - Guayaquil | Sun, Jul 19 | avianca
        $372
        27% off
        $509 $372
      • GYE 2:05 PM
        1h 50m
        Nonstop
        MDE 3:55 PM
        Guayaquil - Medellin | Wed, Jul 29 | avianca
        MDE 9:05 PM
        11h 50m
        1 stop
        GYE 8:55 AM
        Medellin - Guayaquil | Sun, Aug 2 | avianca
        $372
        27% off
        $509 $372
      • GYE 8:27 AM
        5h 48m
        1 stop
        MDE 2:15 PM
        Guayaquil - Medellin | Wed, Jun 10 | Copa Airlines
        MDE 6:20 PM
        17h
        1 stop
        GYE 11:20 AM
        Medellin - Guayaquil | Tue, Jun 16 | Copa Airlines
        $375
        26% off
        $509 $375
      • GYE 4:12 AM
        6h 43m
        1 stop
        MDE 10:55 AM
        Guayaquil - Medellin | Wed, Jul 8 | Copa Airlines
        MDE 12:40 PM
        10h 58m
        1 stop
        GYE 11:38 PM
        Medellin - Guayaquil | Fri, Jul 10 | Copa Airlines
        $376
        26% off
        $509 $376
      • GYE 1:00 PM
        17h 25m
        1 stop
        MDE 2:00 PM
        Guayaquil - Medellin | Tue, Jun 9 | Normal Airline
        MDE 3:00 PM
        6h
        Nonstop
        GYE 4:00 PM
        Medellin - Guayaquil | Thu, Jun 11 | Normal Airline
        Find more flights
        Find more flights
      • Cheapest nonstop
        GYE 1:40 PM
        1h 50m
        Nonstop
        MDE 3:30 PM
        Guayaquil - Medellin | Mon, Jul 20 | avianca
        $184 $259
        28% off
        28% off
        $259 $184
      • GYE 2:05 PM
        1h 50m
        Nonstop
        MDE 3:55 PM
        Guayaquil - Medellin | Wed, Jul 22 | avianca
        $184 $259
        28% off
        28% off
        $259 $184
      • GYE 1:40 PM
        1h 50m
        Nonstop
        MDE 3:30 PM
        Guayaquil - Medellin | Fri, Jul 31 | avianca
        $189 $259
        27% off
        27% off
        $259 $189
      • GYE 1:40 PM
        1h 50m
        Nonstop
        MDE 3:30 PM
        Guayaquil - Medellin | Mon, Jun 15 | avianca
        $191
        26% off
        $259 $191
      • GYE 6:27 PM
        13h 48m
        1 stop
        MDE 8:15 AM
        Guayaquil - Medellin | Wed, Jul 22 | Copa Airlines
        $187
        28% off
        $259 $187
      • GYE 4:23 AM
        10h 22m
        1 stop
        MDE 2:45 PM
        Guayaquil - Medellin | Sat, Jul 18 | Copa Airlines
        $188
        27% off
        $259 $188
      • GYE 8:27 AM
        6h 18m
        1 stop
        MDE 2:45 PM
        Guayaquil - Medellin | Mon, Jul 20 | Copa Airlines
        $188
        27% off
        $259 $188
      • GYE 8:27 AM
        14h 23m
        1 stop
        MDE 10:50 PM
        Guayaquil - Medellin | Wed, Jun 10 | Copa Airlines
        $190
        27% off
        $259 $190
      • GYE 4:13 AM
        10h 32m
        1 stop
        MDE 2:45 PM
        Guayaquil - Medellin | Sat, Aug 1 | Copa Airlines
        $190
        27% off
        $259 $190
      • GYE 4:13 AM
        16h 22m
        1 stop
        MDE 8:35 PM
        Guayaquil - Medellin | Sun, Aug 2 | Copa Airlines
        $190
        27% off
        $259 $190
      • GYE 1:00 PM
        17h 25m
        1 stop
        MDE 2:00 PM
        Guayaquil - Medellin | Tue, Jun 9 | Normal Airline
        Find more flights
        Find more flights

Displayed flight fares from Guayaquil to Medellin are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

Flight Info | Guayaquil to Medellin

The distance between Guayaquil and Medellin is approximately 1,048.08 km. It takes around 1 hour 50 minutes on average to fly from Guayaquil to Medellin. Based on Trip.com's data travel demand peaks in January. The off-season for travel is November.

Cheapest one-way flight price$184
Cheapest round-trip ticket price$349
Off-season for travelNovember
Peak season for travelJanuary
Flight distance1,048.08 km
Average flight time1 hour 50 minutes
Popular airlineavianca
Flight statistics for the Guayaquil–Medellin route are based on aggregated booking data from Trip.com over the past 12 months.

Trip.com price insights on flights from Guayaquil to Medellin

Which month has the cheapest one-way flights from Guayaquil to Medellin?

The average price of one-way flights from Guayaquil to Medellin purchased by Trip.com users by month over the past 12 months.

Based on Trip.com’s data, the cheapest month for flights from Guayaquil to Medellin is August, with an average price of $153; while the month with the highest flight price is usually January, with an average price of up to $395.

$395
$274
$153
$32
    Cheapest
  • $181
    Jun
  • $188
    Jul
  • $153
    Aug
  • $181
    Sep
  • $196
    Oct
  • $208
    Nov
  • $181
    Dec
  • $395
    Jan
  • $213
    Feb
  • $221
    Mar
  • $321
    Apr
  • $310
    May

When is the cheapest day to fly from Guayaquil to Medellin during Juneteenth National Independence Day?

Data is based on the lowest one-way price from Guayaquil to Medellin during Juneteenth National Independence Day on Trip.com in the past 3 days.

Juneteenth National Independence Day is scheduled for Jun 19. The cheapest flights from Guayaquil to Medellin are available on Jun 19, with fares starting at $196.

$211
$204
$196
$189
    Cheapest
  • $210
    15
    Jun
  • $203
    16
  • $203
    17
  • $210
    18
  • $196
    19
  • $211
    20
  • $201
    21

Frequently Asked Questions

  • What are the cheapest flights from Guayaquil to Medellin (GYE-MDE)?

    Based on Trip.com data, avianca offers one-way fares as low as $184 on Cheapest nonstop routes (e.g. GYE to MDE on Mon, Jul 20), while avianca offers Cheapest nonstop round-trips from $349 departing on Mon, Jun 8 and returning on Mon, Jun 15.
  • At the moment, you can catch a nonstop flight from Guayaquil to Medellin with the following airlines, including: avianca Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.
  • It takes around 1 hour 50 minutes to fly from Guayaquil (GYE) to Medellin (MDE).
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Guayaquil to Medellin is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • Based on Trip.com data in the past 4 weeks, there is 1 flight per week flying from Guayaquil to Medellin. You can check the weekly schedule for popular airlines on this route below: avianca: -/-/-/-/-/-/- -- AV5098 (13:50)
  • To find best deals on flights from Guayaquil to Medellin, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Mon, Jul 20, with one-way flights priced at just $184.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is avianca.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Medellin travel is around January.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Guayaquil to Medellin is November, when demand for travel is lower.
  • After crunching the numbers on our June flight calendar, it's currently cheapest to fly from Guayaquil to Medellin on June 10, 2026 with avianca, with prices starting at $358.
  • You can land at any one of the following hubs in Medellin, with José Joaquín de Olmedo International Airport to Jose Maria Cordova International Airport (GYE-MDE) is by far the most common option on this route: Jose Maria Cordova International Airport (MDE) Olaya Herrera Airport (EOH).
  • The time difference between Medellin and Guayaquil is 0h.
  • Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

Explore More Popular Flights

Note: Prices shown on this page are estimated lowest price and include all taxes and fees found in the last 24 hours.

Book with no extra fees

Prices displayed in this page are all-inclusive prices (incl. taxes, fuel surcharge, civil aviation development fund, etc) with all fees confirmed before payment. Fees for luggage, meals, WLAN, or other additional services are also included as shown in the flight cards.

Real-time pricing updates

Prices, availability, and travel information on this page were updated within last 24 hours—even in real-time. The more popular the route, the more precise the data.

Change & Cancellation Policy

Trip.com displays flight cancellation and change policies for each flight ticket during the booking process, including fees and applicable conditions. Please check the following scenarios:
Voluntary cancellation/change:
To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy.
Cancellation/change due to a flight schedule change:
If the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.