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Flights from Guayaquil to Santiago Starting at $171

We've found these cheap flights for you. You can book one-way or round-trip flight tickets.

  • One way
  • Round-trip

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

When is the cheapest time to fly from Guayaquil to Santiago?

We monitor flight fares to help you find the best deals effortlessly

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.
Find cheap airlines flights from Guayaquil to Santiago

Compare prices, find the option that best suits your travel needs, and enjoy a comfortable journey with a trusted airline.

JetSMART Airlines
From $171
LATAM Airlines
From $186
Copa Airlines
From $187
Avianca
From $223
ANA airlines

Find more flights and airlines

Alternative Cheap Routes from Guayaquil to Santiago

Searching for potential routes that might be cheaper and faster? Check out these alternative flights from Guayaquil to Santiago.

  • Cheapest
    JetSMART Airlines
    GYE
    16:56
    10h 5m
    1 transfer
    SCL
    04:01
    Jose Joaquin De Olmedo International Airport - Arturo Merino Benitez Airport
    Sat, Jun 1JetSMART Airlines
    $171
  • JetSMART Airlines
    GYE
    16:56
    10h 5m
    1 transfer
    SCL
    04:01
    Jose Joaquin De Olmedo International Airport - Arturo Merino Benitez Airport
    Sat, Jun 1JetSMART Airlines
    $171
    Find More Flights

Frequently Asked Questions

  • When are flight tickets from Guayaquil (GYE) to Santiago (SCL) the cheapest?

    Airlines adjust prices for flights from Guayaquil to Santiago based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.
  • How much do flights from Guayaquil (GYE) to Santiago (SCL) cost?

    According to Trip.com's data, the lowest price is around $470.
  • How long does it take to fly from Guayaquil (GYE) to Santiago (SCL) and what is the distance?

    It takes around 4 hours 53 minutes to fly from Guayaquil (GYE) to Santiago (SCL).
  • What is the transportation method from the main airport to downtown in Santiago?

    • The distance from Arturo Merino Benitez Airport to downtown is about 13km. It takes about 30 minutes by taxi.
  • What are the most popular airlines that fly from Guayaquil (GYE) to Santiago (SCL)?

    Airlines with flights from Guayaquil (GYE) to Santiago (SCL): LATAM Airlines.

Travel Info | Guayaquil to Santiago

Cheapest nonstop flight price

$170

Cheapest round-trip ticket price

$355

Off-season for travel

April

Peak season for travel

September