$125 Cheap Flights from Key West to San Francisco
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Flights from Key West to San Francisco
Cheap flight deals from Key West to San Francisco
We've found these cheap flights for you. You can book one-way or round-trip flight tickets.
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EYW 6:10 PM9h 9m1 stopsSFO 12:19 AMKey West - San Francisco | Thu, Apr 3 | Delta Air Lines
SFO 6:00 AM8h 15m1 stopsEYW 5:15 PMSan Francisco - Key West | Wed, Apr 9 | Delta Air Lines$278 $51346% OFF46% OFF$513 $278 -
EYW 6:15 PM9h 7m1 stopsSFO 12:22 AMKey West - San Francisco | Tue, Apr 1 | Delta Air Lines
SFO 6:00 AM8h 15m1 stopsEYW 5:15 PMSan Francisco - Key West | Tue, Apr 8 | Delta Air Lines$303 $51341% OFF41% OFF$513 $303
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EYW 4:15 PM9h 17m1 stopsSFO 10:32 PMKey West - San Francisco | Wed, Apr 30 | Delta Air Lines
SFO 6:15 AM8h 15m1 stopsEYW 5:30 PMSan Francisco - Key West | Wed, May 7 | Delta Air Lines$304 $51341% OFF41% OFF$513 $304
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EYW 1:51 PM9h 18m1 stopsSFO 8:09 PMKey West - San Francisco | Wed, May 21 | Delta Air Lines
SFO 6:15 AM8h 15m1 stopsEYW 5:30 PMSan Francisco - Key West | Wed, May 28 | Delta Air Lines$33036% OFF$513 $330
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EYW 4:04 PM11h 11m1 stopsSFO 12:15 AMKey West - San Francisco | Thu, Apr 17 | United Airlines
SFO 10:46 PM9h 29m1 stopsEYW 11:15 AMSan Francisco - Key West | Fri, Apr 25 | United Airlines$33834% OFF$513 $338 -
EYW 6:10 PM9h 9m1 stopsSFO 12:19 AMKey West - San Francisco | Tue, Apr 8 | Delta Air Lines
SFO 6:00 AM8h 17m1 stopsEYW 5:17 PMSan Francisco - Key West | Tue, Apr 15 | Delta Air Lines$34034% OFF$513 $340
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EYW 8:45 AM17h 57m1 stopsSFO 11:42 PMKey West - San Francisco | Sun, Apr 20 | United Airlines
SFO 11:35 PM15h 30m1 stopsEYW 6:05 PMSan Francisco - Key West | Sat, Apr 26 | Jetblue Airways$34533% OFF$513 $345
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EYW 6:10 PM8h 4m1 stopsSFO 11:14 PMKey West - San Francisco | Thu, Apr 10 | Delta Air Lines
SFO 10:47 PM9h 41m1 stopsEYW 11:28 AMSan Francisco - Key West | Mon, Apr 14 | Delta Air Lines$34832% OFF$513 $348
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EYW 12:25 PM8h 42m1 stopsSFO 6:07 PMKey West - San Francisco | Tue, Apr 22 | Delta Air Lines
SFO 6:00 AM8h 17m1 stopsEYW 5:17 PMSan Francisco - Key West | Mon, Apr 28 | Delta Air Lines$36228% OFF$513 $362
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EYW 7:00 AM9h 44m1 stopsSFO 1:44 PMKey West - San Francisco | Wed, Apr 9 | Delta Air Lines
SFO 6:00 AM9h 36m1 stopsEYW 6:36 PMSan Francisco - Key West | Sun, Apr 13 | Delta Air Lines$36428% OFF$513 $364
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EYW 1:00 PM17h 25m1 stopsSFO Invalid DateKey West - San Francisco | Tue, Apr 1 | Normal Airline
SFO 3:00 PM6hNonstopEYW 4:00 PMSan Francisco - Key West | Thu, Apr 3 | Normal AirlineFind More FlightsFind More Flights
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EYW 6:15 PM9h 7m1 stopsSFO 12:22 AMKey West - San Francisco | Wed, Apr 2 | Delta Air Lines$125 $29757% OFF57% OFF$297 $125
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EYW 3:00 PM9h 41m1 stopsSFO 9:41 PMKey West - San Francisco | Fri, May 2 | Delta Air Lines$125 $29757% OFF57% OFF$297 $125
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EYW 6:13 PM8h 18m1 stopsSFO 11:31 PMKey West - San Francisco | Thu, May 1 | Delta Air Lines$128 $29756% OFF56% OFF$297 $128
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EYW 7:40 PM28h 50m1 stopsSFO 9:30 PMKey West - San Francisco | Mon, Mar 31 | United Airlines$14153% OFF$297 $141
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EYW 7:40 PM28h 50m1 stopsSFO 9:30 PMKey West - San Francisco | Mon, Mar 31 | Silver Airways$14252% OFF$297 $142 -
EYW 8:45 AM28h 24m1 stopsSFO 10:09 AMKey West - San Francisco | Fri, May 2 | United Airlines$15648% OFF$297 $156
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EYW 8:45 AM28h 24m1 stopsSFO 10:09 AMKey West - San Francisco | Fri, May 2 | Silver Airways$15747% OFF$297 $157
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EYW 4:04 PM11h 11m1 stopsSFO 12:15 AMKey West - San Francisco | Wed, Apr 30 | United Airlines$17342% OFF$297 $173
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EYW 4:04 PM11h 11m1 stopsSFO 12:15 AMKey West - San Francisco | Thu, Apr 10 | United Airlines$17541% OFF$297 $175
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EYW 8:45 AM18h 23m1 stopsSFO 12:08 AMKey West - San Francisco | Thu, May 1 | Silver Airways$21128% OFF$297 $211
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EYW 1:00 PM17h 25m1 stopsSFO Invalid DateKey West - San Francisco | Tue, Apr 1 | Normal AirlineFind More FlightsFind More Flights
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Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.
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Frequently Asked Questions
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When are flight tickets from Key West (EYW) to San Francisco (SFO) the cheapest?
Airlines adjust prices for flights from Key West to San Francisco based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays. -
How much do flights from Key West (EYW) to San Francisco (SFO) cost?
According to Trip.com's data, the lowest price is around $565. -
What is the transportation method from the main airport to downtown in San Francisco?
- The distance from San Francisco Intl. Airport to downtown is about 17 km. It takes about 30 minutes by taxi.
How to find a cheap flight from Key West to San Francisco
Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Key West to San Francisco. Book your flights at the right time and save more.
Be flexible with your travel dates to get the cheapest Key West to San Francisco ticket.
Tap "Date" in the flight search bar to browse the calendar and find airfare from Key West to San Francisco for the next six months in 2025. If you're looking to fly within the next three months, the lowest fare is $125 for a one-way ticket on Wed, Apr 2.
Compare cheap Key West to San Francisco flight deals from hundreds of airlines.
Our powerful search system compares prices from over 500 airlines. So you can find the cheapest flights from Key West to San Francisco. The most affordable airline currently operating on this route is Delta Air Lines.
Set up a Price Alert to track fare drops.
Set up a Price Alert for your Key West to San Francisco route to track ticket prices effortlessly—no need to check manually every day.
Don't miss out on cheap Key West to San Francisco flight deals and promo codes.
Stay updated on the latest deals with Trip.com Deals and Promo Codes for cheap flights. Sign up for a free membership to unlock even more exclusive flight discounts.
Book early or wait unitl the last minute to fine the best fares.
It's always better to book early! Airlines typically release their lowest fares about a year before departure, so check as soon as flights become available. If you miss that window, you may still find great deals closer to your travel date.
Search for flights on the go.
For the best booking experience on the go, download Trip.com and search for cheap flights from Key West to San Francisco to access exclusive deals just for you.
Flight Info | Key West to San Francisco
| Cheapest one-way flight price | $124 |
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| Off-season for travel | May |
| Peak season for travel | January |
| Flight distance | 4,094.93 km |
| Popular airline | Silver Airways |
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