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Flights from Madrid to Santiago

Hi, I've summed up all the key info for Madrid to Santiago flights

Cheapest one-way

$ 525
Azul Airlines Tue, Sep 22

48% below next 30d avg. ($1,013)

Cheapest round-trip

$ 754
avianca Mon, Sep 14

47% below next 30d avg. ($1,432)

When to travel

September Cheapest month
July Peak month

Fastest flight

12h 20m 1h 22m faster than avg. (13h 42m)

Recommended airlines

With a lowest one-way fare of $525 , travelers can expect an average price of $1,013 for upcoming trips, while round-trip tickets start at $754 . Flights typically take around 13h 42m , but the fastest nonstop option completes the journey in just 12h 20m minutes. There are 56 flights weekly on this route. You can arrive at any of the following airports in Santiago: Arturo Merino Benitez International Airport (SCL) . Flights from Madrid Barajas Airport to Arturo Merino Benitez International Airport (MAD-SCL) are by far the most popular option for this route. To secure the best rates, booking 40 days in advance is recommended, and the cheapest travel days are Tuesday, Wednesday, and Saturday .

Updated 4d ago · This content is an AI-powered summary based on Trip.com data. Prices and availability are subject to change. Please refer to actual prices, availability, and travel conditions.

Explore the cheapest one-way and round-trip flights from Madrid to Santiago over the next 90 days, with one-way fares from $525 and round-trip from $754. Based on Trip.com's latest 7-day flight data.

      • Cheapest nonstop
        MAD 11:15 AM
        13h 30m
        Nonstop
        SCL 8:45 PM
        Madrid - Santiago | Thu, Nov 5 | LATAM Airlines
        SCL 12:50 PM
        12h 35m
        Nonstop
        MAD 5:25 AM
        Santiago - Madrid | Tue, Nov 10 | Iberia
        $985 $1,052
        6% off
        6% off
        $1,052 $985
      • MAD 11:15 AM
        13h 30m
        Nonstop
        SCL 8:45 PM
        Madrid - Santiago | Wed, Nov 11 | LATAM Airlines
        SCL 12:50 AM
        12h 40m
        Nonstop
        MAD 5:30 PM
        Santiago - Madrid | Wed, Nov 18 | Iberia
        $988 $1,052
        6% off
        6% off
        $1,052 $988
      • MAD 11:05 AM
        18h 15m
        1 stop
        SCL 12:20 AM
        Madrid - Santiago | Mon, Sep 14 | avianca
        SCL 7:40 AM
        17h 30m
        1 stop
        MAD 6:10 AM
        Santiago - Madrid | Fri, Sep 18 | avianca
        $754 $1,052
        28% off
        28% off
        $1,052 $754
      • MAD 9:50 AM
        27h 25m
        1 stop
        SCL 8:15 AM
        Madrid - Santiago | Wed, Oct 21 | Delta Air Lines
        SCL 8:40 PM
        33h 15m
        1 stop
        MAD 9:55 AM
        Santiago - Madrid | Sat, Oct 24 | Delta Air Lines
        $859
        18% off
        $1,052 $859
      • MAD 9:50 AM
        27h 25m
        1 stop
        SCL 8:15 AM
        Madrid - Santiago | Mon, Oct 12 | Delta Air Lines
        SCL 8:40 PM
        34h 35m
        1 stop
        MAD 12:15 PM
        Santiago - Madrid | Sun, Oct 18 | Delta Air Lines
        $860
        18% off
        $1,052 $860
      • MAD 1:25 PM
        29h 45m
        2 stops
        SCL 3:10 PM
        Madrid - Santiago | Thu, Nov 5 | Air Canada
        SCL 12:50 AM
        12h 40m
        Nonstop
        MAD 5:30 PM
        Santiago - Madrid | Sat, Nov 7 | Iberia
        $864
        18% off
        $1,052 $864
      • MAD 12:40 AM
        25h 10m
        1 stop
        SCL 9:50 PM
        Madrid - Santiago | Thu, Nov 5 | LATAM Airlines
        SCL 12:50 PM
        12h 35m
        Nonstop
        MAD 5:25 AM
        Santiago - Madrid | Sat, Nov 7 | Iberia
        $893
        15% off
        $1,052 $893
      • MAD 12:40 AM
        18h 20m
        1 stop
        SCL 3:00 PM
        Madrid - Santiago | Tue, Nov 10 | LATAM Airlines
        SCL 12:50 PM
        12h 35m
        Nonstop
        MAD 5:25 AM
        Santiago - Madrid | Tue, Nov 17 | Iberia
        $894
        15% off
        $1,052 $894
      • MAD 10:10 AM
        23h 25m
        1 stop
        SCL 5:35 AM
        Madrid - Santiago | Sun, Nov 8 | avianca
        SCL 12:50 AM
        12h 40m
        Nonstop
        MAD 5:30 PM
        Santiago - Madrid | Thu, Nov 12 | Iberia
        $902
        14% off
        $1,052 $902
      • MAD 1:20 AM
        32h 10m
        1 stop
        SCL 5:30 AM
        Madrid - Santiago | Mon, Nov 9 | avianca
        SCL 10:00 PM
        13h
        Nonstop
        MAD 3:00 PM
        Santiago - Madrid | Thu, Nov 12 | LATAM Airlines
        $928
        12% off
        $1,052 $928
      • MAD 11:05 AM
        23h 40m
        1 stop
        SCL 5:45 AM
        Madrid - Santiago | Wed, Oct 21 | avianca
        SCL 8:00 PM
        12h 55m
        Nonstop
        MAD 12:55 PM
        Santiago - Madrid | Sat, Oct 24 | LATAM Airlines
        $929
        12% off
        $1,052 $929
      • MAD 4:20 PM
        36h 45m
        1 stop
        SCL 1:05 AM
        Madrid - Santiago | Sun, Oct 25 | avianca
        SCL 12:50 AM
        12h 40m
        Nonstop
        MAD 5:30 PM
        Santiago - Madrid | Fri, Oct 30 | Iberia
        $930
        12% off
        $1,052 $930
      • MAD 1:00 PM
        17h 25m
        1 stop
        SCL 2:00 PM
        Madrid - Santiago | Tue, Sep 15 | Normal Airline
        SCL 3:00 PM
        6h
        Nonstop
        MAD 4:00 PM
        Santiago - Madrid | Thu, Sep 17 | Normal Airline
        Find more flights
        Find more flights
      • Cheapest nonstop
        MAD 11:35 PM
        12h 20m
        Nonstop
        SCL 7:55 AM
        Madrid - Santiago | Mon, Nov 2 | LATAM Airlines
        $587 $770
        24% off
        24% off
        $770 $587
      • MAD 1:20 PM
        13h 20m
        Nonstop
        SCL 10:40 PM
        Madrid - Santiago | Mon, Nov 2 | Iberia
        $723 $770
        6% off
        6% off
        $770 $723
      • MAD 1:50 PM
        38h 30m
        1 stop
        SCL 11:20 PM
        Madrid - Santiago | Tue, Sep 22 | Azul Airlines
        $525 $770
        32% off
        32% off
        $770 $525
      • MAD 2:55 PM
        40h 40m
        1 stop
        SCL 3:35 AM
        Madrid - Santiago | Mon, Nov 9 | World2Fly Airlines
        $527
        32% off
        $770 $527
      • MAD 1:45 AM
        21h
        1 stop
        SCL 5:45 PM
        Madrid - Santiago | Fri, Sep 18 | LATAM Airlines
        $595
        23% off
        $770 $595
      • MAD 6:35 AM
        26h 55m
        1 stop
        SCL 5:30 AM
        Madrid - Santiago | Sun, Nov 8 | avianca
        $608
        21% off
        $770 $608
      • MAD 1:50 PM
        26h 40m
        1 stop
        SCL 11:30 AM
        Madrid - Santiago | Thu, Sep 24 | Azul Airlines
        $610
        21% off
        $770 $610
      • MAD 1:50 PM
        26h 40m
        1 stop
        SCL 11:30 AM
        Madrid - Santiago | Tue, Sep 29 | Azul Airlines
        $617
        20% off
        $770 $617
      • MAD 1:50 PM
        32h 26m
        1 stop
        SCL 5:16 PM
        Madrid - Santiago | Thu, Oct 1 | Azul Airlines
        $627
        19% off
        $770 $627
      • MAD 12:45 AM
        17h 20m
        1 stop
        SCL 2:05 PM
        Madrid - Santiago | Sun, Nov 8 | LATAM Airlines
        $629
        18% off
        $770 $629
      • MAD 8:10 AM
        35h
        1 stop
        SCL 3:10 PM
        Madrid - Santiago | Sun, Nov 1 | avianca
        $635
        18% off
        $770 $635
      • MAD 2:45 PM
        15h 45m
        1 stop
        SCL 1:30 AM
        Madrid - Santiago | Fri, Sep 25 | Boliviana De Aviación
        $661
        14% off
        $770 $661
      • MAD 1:00 PM
        17h 25m
        1 stop
        SCL 2:00 PM
        Madrid - Santiago | Tue, Sep 15 | Normal Airline
        Find more flights
        Find more flights

Flight.News
Flights from Madrid to Santiago operate an average of 15 times per day over the past 7 days, with a 22.3% on-time departure rate and a 94.6% on-time arrival rate.

Which airlines are the most popular for Madrid to Santiago flights?

You can choose from 1 airlines that fly from Madrid to Santiago, including LATAM Airlines, Azul Airlines has lowest fares on this route.
LATAM Airlines logo LATAM Airlines
Airlines are determined based on actual purchased flight tickets from Madrid to Santiago according to previous 12 months data from Trip.com.

Flight Info | Madrid to Santiago

The distance between Madrid and Santiago is approximately 10,717.78 km. It takes around 13 hours 42 minutes on average to fly from Madrid to Santiago. Based on Trip.com's data travel demand peaks in July. The off-season for travel is September.

Cheapest one-way flight price $525
Cheapest round-trip ticket price $754
Off-season for travel September
Peak season for travel July
Flight distance 10,717.78 km
Average flight time 13 hours 42 minutes
Popular airline LATAM Airlines
Frequency ～16/week
Flight statistics for the Madrid–Santiago route are based on aggregated booking data from Trip.com over the past 12 months.

Trip.com price insights on flights from Madrid to Santiago

Which month has the cheapest one-way flights from Madrid to Santiago?

The average price of one-way flights from Madrid to Santiago purchased by Trip.com users by month over the past 12 months.

Based on Trip.com’s data, the cheapest month for flights from Madrid to Santiago is May, with an average price of $515; while the month with the highest flight price is usually July, with an average price of up to $991.

$991
$753
$515
$277
    Cheapest
  • $670
    Sep
  • $763
    Oct
  • $722
    Nov
  • $735
    Dec
  • $690
    Jan
  • $749
    Feb
  • $551
    Mar
  • $581
    Apr
  • $515
    May
  • $647
    Jun
  • $991
    Jul
  • $704
    Aug

What is the cheapest month for round-trip flights from Madrid to Santiago?

Average price of round-trip flights from Madrid to Santiago purchased by Trip.com users by month over the past 12 months

According to historical data from Trip.com, the lowest prices for flights from Madrid to Santiago are found during April, with an average price of $1,056. Conversely, the highest prices are found during July, with an average price of up to $1,591.

$1,591
$1,324
$1,056
$789
    Cheapest
  • $1,446
    Sep
  • $1,412
    Oct
  • $1,187
    Nov
  • $1,525
    Dec
  • $1,091
    Jan
  • $1,176
    Feb
  • $1,082
    Mar
  • $1,056
    Apr
  • $1,187
    May
  • $1,190
    Jun
  • $1,591
    Jul
  • $1,324
    Aug

When is the cheapest day to fly from Madrid to Santiago during Columbus Day?

Data is based on the lowest one-way price from Madrid to Santiago during Columbus Day on Trip.com in the past 3 days.

Columbus Day is scheduled for Oct 12. The cheapest flights from Madrid to Santiago are available on Oct 13, with fares starting at $755.

$930
$843
$755
$668
    Cheapest
  • $930
    8
    Oct
  • $820
    9
  • $762
    10
  • $919
    11
  • $771
    12
  • $755
    13
  • $785
    14

Frequently Asked Questions

  • What are the cheapest flights from Madrid to Santiago (MAD-SCL)?

    Based on Trip.com data, Azul Airlines offers one-way fares as low as $525 on Cheapest nonstop routes (e.g. MAD to SCL on Tue, Sep 22), while avianca offers Cheapest nonstop round-trips from $754 departing on Mon, Sep 14 and returning on Fri, Sep 18.
  • At the moment, you can catch a nonstop flight from Madrid to Santiago with the following airlines, including: LATAM Airlines Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.
  • It takes around 13 hours 42 minutes to fly from Madrid (MAD) to Santiago (SCL).
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Madrid to Santiago is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • Based on Trip.com data in the past 4 weeks, there is 56 flight per week flying from Madrid to Santiago. You can check the weekly schedule for popular airlines on this route below: LATAM Airlines: S/M/T/W/T/F/S -- LA705 (00:10)
  • To find best deals on flights from Madrid to Santiago, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Tue, Sep 22, with one-way flights priced at just $525.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is LATAM Airlines.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Santiago travel is around July.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Madrid to Santiago is September, when demand for travel is lower.
  • After crunching the numbers on our September flight calendar, it's currently cheapest to fly from Madrid to Santiago on September 18, 2026 with LATAM Airlines, with prices starting at $859.
  • You can arrive at any of the following airports in Santiago: Arturo Merino Benitez International Airport (SCL). Flights from Madrid Barajas Airport to Arturo Merino Benitez International Airport (MAD-SCL) are by far the most popular option for this route.
  • The time difference between Santiago and Madrid is 5h.
  • Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.
  • Based on Trip.com data for flights departing in the next 30 days, the average one-way fare from Madrid to Santiago is $1,013. Fares vary by travel date, airline and availability.
  • Based on Trip.com data for travel in the next 30 days, the average round-trip fare from Madrid to Santiago is $1,432. The final price depends on the outbound and return dates, airline and fare conditions.
  • Enter Madrid and Santiago, choose your travel dates and passengers, then compare flights by price, duration and baggage. Select a fare, review the change and cancellation rules, enter traveler details and complete payment to receive your confirmation.
  • Sky Airlineare the most popular budget airlines flying from Madrid to Santiago. Check baggage, seat and payment fees before comparing the final price.

Explore More Popular Flights

Note: Prices shown on this page are estimated lowest price and include all taxes and fees found in the last 24 hours.

Book with no extra fees

Prices displayed in this page are all-inclusive prices (incl. taxes, fuel surcharge, civil aviation development fund, etc) with all fees confirmed before payment. Fees for luggage, meals, WLAN, or other additional services are also included as shown in the flight cards.

Real-time pricing updates

Prices, availability, and travel information on this page were updated within last 24 hours—even in real-time. The more popular the route, the more precise the data.

Change & Cancellation Policy

Trip.com displays flight cancellation and change policies for each flight ticket during the booking process, including fees and applicable conditions. Please check the following scenarios:
Voluntary cancellation/change:
To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy.
Cancellation/change due to a flight schedule change:
If the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.