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Flights from Medellin to Panama City Starting at $102

We've found these cheap flights for you. You can book one-way or round-trip flight tickets.

  • One way
  • Round-trip

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

When is the cheapest time to fly from Medellin to Panama City?

We monitor flight fares to help you find the best deals effortlessly

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.
Find cheap airlines flights from Medellin to Panama City

Compare prices, find the option that best suits your travel needs, and enjoy a comfortable journey with a trusted airline.

JetSMART
From $130
Copa Airlines
From $132
Avianca
From $138
LATAM Airlines
From $168
Aero Republica S.A.
From $300
A.P.G. Distribution System
From $367
American Airlines
From $455
United Airlines
From $752
ANA airlines

Find more flights and airlines

Alternative Cheap Routes from Medellin to Panama City

Searching for potential routes that might be cheaper and faster? Check out these alternative flights from Medellin to Panama City.

  • Cheapest
    Avianca
    MDE
    16:18
    4h 27m
    1 transfer
    PTY
    20:45
    Jose Marie Cordova Airport - Tocumen International Airport
    Wed, Apr 24Avianca
    $138
  • APG Airline
    EOH
    10:40
    6h 23m
    1 transfer
    PTY
    17:03
    Olaya Herrera Airport - Tocumen International Airport
    Thu, May 2APG Airline
    $367
  • APG Airline
    EOH
    10:40
    6h 23m
    1 transfer
    PTY
    17:03
    Olaya Herrera Airport - Tocumen International Airport
    Thu, May 2APG Airline
    $367
    Find More Flights

Frequently Asked Questions

  • When are flight tickets from Medellin (MDE) to Panama City (PTY) the cheapest?

    Airlines adjust prices for flights from Medellin to Panama City based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.
  • How much do flights from Medellin (MDE) to Panama City (PTY) cost?

    According to Trip.com's data, the lowest price is around $196.
  • How long does it take to fly from Medellin (MDE) to Panama City (PTY) and what is the distance?

    It takes around 1 hour 27 minutes to fly from Medellin (MDE) to Panama City (PTY).
  • What is the transportation method from the main airport to downtown in Panama City?

    • The distance from Tocumen International Airport to downtown is about 16km. It takes about 30 minutes by taxi.
    • The distance from Albrook "Marcos A. Gelabert" International Airport to downtown is about 5km. It takes about 20 minutes by taxi.
  • What are the most popular airlines that fly from Medellin (MDE) to Panama City (PTY)?

    Airlines with flights from Medellin (MDE) to Panama City (PTY): Copa Airlines, KLM, Turkish Airlines and United Airlines.

How to find a cheap flight from Medellin to Panama City

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Medellin to Panama City. Book your flights at the right time and save more.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com

Travel Info | Medellin to Panama City

Cheapest nonstop flight price

$102

Cheapest round-trip ticket price

$223

Off-season for travel

January

Peak season for travel

October

Flight distance

530.92km

Average flight time

1 hour 27 minutes

Popular airline

Avianca