Trip.com
>
Flights
>
Flights to United States
>
Flights to Texas
>
Flights to San Antonio
Hotels in San Antonio
>
Flights from Medford to San Antonio

Find flight deals from Medford to San Antonio for the next 3 months. Book one way flights from $198 or round trip flights from $333.

      • MFR 7:50 PM
        7h 10m
        1 stop
        SAT 5:00 AM
        Medford - San Antonio | Sat, Aug 15 | Alaska Airlines
        SAT 6:03 PM
        7h 52m
        1 stop
        MFR 11:55 PM
        San Antonio - Medford | Fri, Aug 21 | Delta Air Lines
        $333 $763
        56% off
        56% off
        $763 $333
      • MFR 5:15 AM
        6h 16m
        1 stop
        SAT 1:31 PM
        Medford - San Antonio | Wed, Aug 5 | Delta Air Lines
        SAT 6:03 PM
        7h 52m
        1 stop
        MFR 11:55 PM
        San Antonio - Medford | Tue, Aug 11 | Delta Air Lines
        $361 $763
        53% off
        53% off
        $763 $361
      • MFR 2:07 PM
        5h 52m
        1 stop
        SAT 9:59 PM
        Medford - San Antonio | Sat, Aug 15 | United Airlines
        SAT 6:03 PM
        7h 52m
        1 stop
        MFR 11:55 PM
        San Antonio - Medford | Fri, Aug 21 | Delta Air Lines
        $388 $763
        49% off
        49% off
        $763 $388
      • MFR 3:40 PM
        6h 11m
        1 stop
        SAT 11:51 PM
        Medford - San Antonio | Sat, Aug 15 | American Airlines
        SAT 6:03 PM
        7h 52m
        1 stop
        MFR 11:55 PM
        San Antonio - Medford | Fri, Aug 21 | Delta Air Lines
        $435
        43% off
        $763 $435
      • MFR 1:23 PM
        8h 35m
        1 stop
        SAT 11:58 PM
        Medford - San Antonio | Fri, Jul 31 | American Airlines
        SAT 7:04 PM
        6h 34m
        1 stop
        MFR 11:38 PM
        San Antonio - Medford | Thu, Aug 6 | American Airlines
        $446
        42% off
        $763 $446
      • MFR 2:07 PM
        5h 52m
        1 stop
        SAT 9:59 PM
        Medford - San Antonio | Sun, Aug 23 | United Airlines
        SAT 4:39 PM
        6h 29m
        1 stop
        MFR 9:08 PM
        San Antonio - Medford | Wed, Aug 26 | United Airlines
        $456
        40% off
        $763 $456
      • MFR 2:11 PM
        8h 18m
        1 stop
        SAT 12:29 AM
        Medford - San Antonio | Thu, Aug 6 | United Airlines
        SAT 4:35 PM
        6h 41m
        1 stop
        MFR 9:16 PM
        San Antonio - Medford | Wed, Aug 12 | United Airlines
        $469
        39% off
        $763 $469
      • MFR 1:10 PM
        8h 45m
        1 stop
        SAT 11:55 PM
        Medford - San Antonio | Fri, Jul 31 | United Airlines
        SAT 7:04 PM
        6h 34m
        1 stop
        MFR 11:38 PM
        San Antonio - Medford | Thu, Aug 6 | American Airlines
        $494
        35% off
        $763 $494
      • MFR 1:10 PM
        8h 45m
        1 stop
        SAT 11:55 PM
        Medford - San Antonio | Sat, Aug 1 | United Airlines
        SAT 4:35 PM
        6h 41m
        1 stop
        MFR 9:16 PM
        San Antonio - Medford | Fri, Aug 7 | United Airlines
        $533
        30% off
        $763 $533
      • MFR 1:23 PM
        8h 35m
        1 stop
        SAT 11:58 PM
        Medford - San Antonio | Thu, Aug 6 | American Airlines
        SAT 3:43 PM
        5h 37m
        1 stop
        MFR 7:20 PM
        San Antonio - Medford | Wed, Aug 12 | American Airlines
        $534
        30% off
        $763 $534
      • MFR 1:00 PM
        17h 25m
        1 stop
        SAT 2:00 PM
        Medford - San Antonio | Tue, Jul 21 | Normal Airline
        SAT 3:00 PM
        6h
        Nonstop
        MFR 4:00 PM
        San Antonio - Medford | Thu, Jul 23 | Normal Airline
        Find more flights
        Find more flights
      • MFR 5:15 AM
        6h 16m
        1 stop
        SAT 1:31 PM
        Medford - San Antonio | Sun, Aug 16 | Delta Air Lines
        $198 $379
        48% off
        48% off
        $379 $198
      • MFR 5:20 AM
        6h 20m
        1 stop
        SAT 1:40 PM
        Medford - San Antonio | Sun, Aug 16 | American Airlines
        $202 $379
        47% off
        47% off
        $379 $202
      • MFR 5:00 AM
        5h 43m
        1 stop
        SAT 12:43 PM
        Medford - San Antonio | Fri, Aug 14 | United Airlines
        $219 $379
        42% off
        42% off
        $379 $219
      • MFR 2:07 PM
        5h 51m
        1 stop
        SAT 9:58 PM
        Medford - San Antonio | Tue, Aug 18 | United Airlines
        $250
        34% off
        $379 $250
      • MFR 2:07 PM
        5h 52m
        1 stop
        SAT 9:59 PM
        Medford - San Antonio | Sat, Aug 15 | United Airlines
        $250
        34% off
        $379 $250
      • MFR 2:07 PM
        5h 52m
        1 stop
        SAT 9:59 PM
        Medford - San Antonio | Sun, Aug 16 | United Airlines
        $251
        34% off
        $379 $251
      • MFR 5:20 AM
        6h 1m
        1 stop
        SAT 1:21 PM
        Medford - San Antonio | Tue, Aug 18 | American Airlines
        $255
        33% off
        $379 $255
      • MFR 1:00 PM
        5h 52m
        1 stop
        SAT 8:52 PM
        Medford - San Antonio | Mon, Aug 17 | United Airlines
        $265
        30% off
        $379 $265
      • MFR 2:11 PM
        8h 18m
        1 stop
        SAT 12:29 AM
        Medford - San Antonio | Fri, Aug 7 | United Airlines
        $265
        30% off
        $379 $265
      • MFR 5:00 AM
        5h 43m
        1 stop
        SAT 12:43 PM
        Medford - San Antonio | Mon, Aug 10 | United Airlines
        $265
        30% off
        $379 $265
      • MFR 1:00 PM
        17h 25m
        1 stop
        SAT 2:00 PM
        Medford - San Antonio | Tue, Jul 21 | Normal Airline
        Find more flights
        Find more flights

Flight Info | Medford to San Antonio

The distance between Medford and San Antonio is approximately 2,605.26 km. Based on Trip.com's data travel demand peaks in July. The off-season for travel is November.

Cheapest one-way flight price$198
Cheapest round-trip ticket price$333
Off-season for travelNovember
Peak season for travelJuly
Flight distance2,605.26 km
Flight statistics for the Medford–San Antonio route are based on aggregated booking data from Trip.com over the past 12 months.

Frequently Asked Questions

  • What are the cheapest flights from Medford to San Antonio (MFR-SAT)?

    Based on Trip.com data, Delta Air Lines offers one-way fares as low as $198 on Cheapest nonstop routes (e.g. MFR to SAT on Sun, Aug 16), while Alaska Airlines offers Cheapest nonstop round-trips from $333 departing on Sat, Aug 15 and returning on Fri, Aug 21.
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Medford to San Antonio is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • To find best deals on flights from Medford to San Antonio, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Sun, Aug 16, with one-way flights priced at just $198.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is Delta Air Lines.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for San Antonio travel is around July.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Medford to San Antonio is November, when demand for travel is lower.
  • After crunching the numbers on our July flight calendar, it's currently cheapest to fly from Medford to San Antonio on July 29, 2026 with American Airlines, with prices starting at $446.
  • The time difference between San Antonio and Medford is 2h.
  • Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

Explore More Popular Flights

Note: Prices shown on this page are estimated lowest price and include all taxes and fees found in the last 24 hours.

Book with no extra fees

Prices displayed in this page are all-inclusive prices (incl. taxes, fuel surcharge, civil aviation development fund, etc) with all fees confirmed before payment. Fees for luggage, meals, WLAN, or other additional services are also included as shown in the flight cards.

Real-time pricing updates

Prices, availability, and travel information on this page were updated within last 24 hours—even in real-time. The more popular the route, the more precise the data.

Change & Cancellation Policy

Trip.com displays flight cancellation and change policies for each flight ticket during the booking process, including fees and applicable conditions. Please check the following scenarios:
Voluntary cancellation/change:
To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy.
Cancellation/change due to a flight schedule change:
If the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.