Cheap Flights from Mendoza to Santiago from $56

Frequently Asked Questions

• What are the cheapest flights from Mendoza to Santiago (MDZ-SCL)?

  Based on Trip.com data, Sky Airline offers one-way fares as low as $56 on Cheapest nonstop routes (e.g. MDZ to SCL on Sun, May 31), while Sky Airline offers Cheapest nonstop round-trips from $89 departing on Thu, May 14 and returning on Mon, May 18.

• Which airlines offer direct flights from Mendoza to Santiago?

  At the moment, you can catch a nonstop flight from Mendoza to Santiago with the following airlines, including: Sky Airline JetSMART LATAM Airlines Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.

• How long does it take to fly from Mendoza (MDZ) to Santiago (SCL) and what is the distance?

  It takes around 2 hours 19 minutes to fly from Mendoza (MDZ) to Santiago (SCL).

• When is the best time to book flights from Mendoza to Santiago?

  By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Mendoza to Santiago is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.

• How many flights are there per week from Mendoza to Santiago?

  Based on Trip.com data in the past 4 weeks, there is 23 flight per week flying from Mendoza to Santiago. You can check the weekly schedule for popular airlines on this route below: Sky Airline: S/-/T/-/-/F/S -- H2528 (21:16) LATAM Airlines: S/-/-/W/T/F/S -- LA435 (11:58)

• How can I find the best deals on flights from Mendoza to Santiago?

  To find best deals on flights from Mendoza to Santiago, you can use various tools on Trip.com:
  · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Sun, May 31, with one-way flights priced at just $56.
  · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is Sky Airline.
  · Set up price alerts to easily monitor ticket prices without having to check every day.
  · Check Trip.com flight deals and promo codes frequently.
  · Avoid peak season unless you book very early. It seems the peak season for Santiago travel is around July.
  · Get exclusive promo codes for Trip.com app users.

• When are flight tickets from Mendoza (MDZ) to Santiago (SCL) the cheapest?

  The cheapest months to fly from Mendoza to Santiago is October, when demand for travel is lower.

• Which upcoming date is cheapest to fly from Mendoza to Santiago on?

  After crunching the numbers on our May flight calendar, it's currently cheapest to fly from Mendoza to Santiago on May 20, 2026 with Sky Airline, with prices starting at $56.

• Which airports can I fly to for Santiago from Mendoza?

  You can land at any one of the following hubs in Santiago, with El Plumerillo International Airport to Arturo Merino Benitez International Airport (MDZ-SCL) is by far the most common option on this route: Arturo Merino Benitez International Airport (SCL).

• Is there any time difference between Mendoza and Santiago?

  The time difference between Santiago and Mendoza is 1h.

• How do I change or cancel my ticket from Mendoza to Santiago?

  Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.