Cheap Flights from Mexico City to Des Moines from $364

Frequently Asked Questions

• What are the cheapest flights from Mexico City to Des Moines (MEX-DSM)?

  Based on Trip.com data, United Airlines offers one-way fares as low as $364 on Cheapest nonstop routes (e.g. MEX to DSM on Wed, Jul 22), while United Airlines offers Cheapest nonstop round-trips from $528 departing on Wed, Aug 19 and returning on Mon, Aug 24.

• Which airlines offer direct flights from Mexico City to Des Moines?

  At the moment, you can catch a nonstop flight from Mexico City to Des Moines with the following airlines, including: Frontier Airlines Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.

• When is the best time to book flights from Mexico City to Des Moines?

  By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Mexico City to Des Moines is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.

• How can I find the best deals on flights from Mexico City to Des Moines?

  To find best deals on flights from Mexico City to Des Moines, you can use various tools on Trip.com:
  · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Wed, Jul 22, with one-way flights priced at just $364.
  · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is United Airlines.
  · Set up price alerts to easily monitor ticket prices without having to check every day.
  · Check Trip.com flight deals and promo codes frequently.
  · Avoid peak season unless you book very early. It seems the peak season for Des Moines travel is around July.
  · Get exclusive promo codes for Trip.com app users.

• When are flight tickets from Mexico City (MEX) to Des Moines (DSM) the cheapest?

  The cheapest months to fly from Mexico City to Des Moines is September, when demand for travel is lower.

• Which upcoming date is cheapest to fly from Mexico City to Des Moines on?

  After crunching the numbers on our July flight calendar, it's currently cheapest to fly from Mexico City to Des Moines on July 21, 2026 with United Airlines, with prices starting at $364.

• Which airports can I fly to for Des Moines from Mexico City?

  You can land at any one of the following hubs in Des Moines, with Mexico City International Airport to Des Moines International Airport (MEX-DSM) is by far the most common option on this route: Des Moines International Airport (DSM).

• Is there any time difference between Mexico City and Des Moines?

  The time difference between Des Moines and Mexico City is 0h.

• How do I change or cancel my ticket from Mexico City to Des Moines?

  Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.