$106 Cheap Flights from Milwaukee to Des Moines
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Flights from Milwaukee to Des Moines
Cheap flight deals from Milwaukee to Des Moines Starting at $106
We've found these cheap flights for you. You can book one-way or round-trip flight tickets.
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Round-trip
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One way
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MKE 1:10 PM4h 9m1 stopsDSM 5:19 PMMilwaukee - Des Moines | Thu, Apr 3 | Delta Air Lines
DSM 5:59 PM3h 46m1 stopsMKE 9:45 PMDes Moines - Milwaukee | Wed, Apr 9 | Delta Air Lines$209 $28827% OFF27% OFF$288 $209 -
MKE 10:55 AM4h 44m1 stopsDSM 3:39 PMMilwaukee - Des Moines | Sat, Mar 29 | Delta Air Lines
DSM 6:52 AM3h 12m1 stopsMKE 10:04 AMDes Moines - Milwaukee | Fri, Apr 4 | Delta Air Lines$215 $28825% OFF25% OFF$288 $215
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MKE 6:34 AM5h 53m1 stopsDSM 12:27 PMMilwaukee - Des Moines | Fri, May 9 | Delta Air Lines
DSM 10:25 AM5h 42m1 stopsMKE 4:07 PMDes Moines - Milwaukee | Tue, May 13 | Delta Air Lines$220 $28824% OFF24% OFF$288 $220
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MKE 10:55 AM5h 32m1 stopsDSM 4:27 PMMilwaukee - Des Moines | Tue, Mar 18 | Delta Air Lines
DSM 6:52 AM3h 18m1 stopsMKE 10:10 AMDes Moines - Milwaukee | Sat, Mar 22 | Delta Air Lines$22422% OFF$288 $224
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MKE 1:10 PM4h 9m1 stopsDSM 5:19 PMMilwaukee - Des Moines | Sat, Apr 5 | Delta Air Lines
DSM 10:22 AM5h 54m1 stopsMKE 4:16 PMDes Moines - Milwaukee | Fri, Apr 11 | Delta Air Lines$23020% OFF$288 $230
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MKE 6:20 AM4h 59m1 stopsDSM 11:19 AMMilwaukee - Des Moines | Wed, Apr 23 | Delta Air Lines
DSM 7:00 AM3h 30m1 stopsMKE 10:30 AMDes Moines - Milwaukee | Thu, Apr 24 | Delta Air Lines$25113% OFF$288 $251
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MKE 2:51 PM6h 29m1 stopsDSM 9:20 PMMilwaukee - Des Moines | Mon, Mar 31 | Delta Air Lines
DSM 6:52 AM3h 12m1 stopsMKE 10:04 AMDes Moines - Milwaukee | Sun, Apr 6 | Delta Air Lines$25611% OFF$288 $256
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MKE 2:51 PM6h 29m1 stopsDSM 9:20 PMMilwaukee - Des Moines | Wed, Mar 19 | Delta Air Lines
DSM 6:52 AM3h 18m1 stopsMKE 10:10 AMDes Moines - Milwaukee | Wed, Mar 26 | Delta Air Lines$2629% OFF$288 $262
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MKE 2:25 PM3h 41m1 stopsDSM 6:06 PMMilwaukee - Des Moines | Tue, Apr 1 | United Airlines
DSM 6:47 PM3h 28m1 stopsMKE 10:15 PMDes Moines - Milwaukee | Mon, Apr 7 | United Airlines$2696% OFF$288 $269 -
MKE 5:30 PM4h 22m1 stopsDSM 9:52 PMMilwaukee - Des Moines | Thu, Apr 3 | United Airlines
DSM 11:38 AM3h 30m1 stopsMKE 3:08 PMDes Moines - Milwaukee | Wed, Apr 9 | United Airlines$2706% OFF$288 $270
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MKE 1:00 PM17h 25m1 stopsDSM Invalid DateMilwaukee - Des Moines | Sun, Mar 16 | Normal Airline
DSM 3:00 PM6hNonstopMKE 4:00 PMDes Moines - Milwaukee | Tue, Mar 18 | Normal AirlineFind More FlightsFind More Flights
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MKE 2:51 PM6h 29m1 stopsDSM 9:20 PMMilwaukee - Des Moines | Tue, Mar 18 | Delta Air Lines$106 $15833% OFF33% OFF$158 $106
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MKE 11:25 AM5h 13m1 stopsDSM 4:38 PMMilwaukee - Des Moines | Wed, Apr 23 | Delta Air Lines$107 $15832% OFF32% OFF$158 $107
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MKE 6:43 AM4h 30m1 stopsDSM 11:13 AMMilwaukee - Des Moines | Thu, Apr 3 | Delta Air Lines$121 $15824% OFF24% OFF$158 $121
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MKE 10:55 AM4h 44m1 stopsDSM 3:39 PMMilwaukee - Des Moines | Sat, Mar 15 | Delta Air Lines$12223% OFF$158 $122
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MKE 2:51 PM6h 29m1 stopsDSM 9:20 PMMilwaukee - Des Moines | Fri, Mar 28 | Delta Air Lines$12223% OFF$158 $122
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MKE 2:48 PM6h 32m1 stopsDSM 9:20 PMMilwaukee - Des Moines | Mon, Mar 17 | Delta Air Lines$12223% OFF$158 $122
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MKE 3:02 PM8h 28m1 stopsDSM 11:30 PMMilwaukee - Des Moines | Tue, Mar 18 | United Airlines$13514% OFF$158 $135
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MKE 5:30 PM4h 22m1 stopsDSM 9:52 PMMilwaukee - Des Moines | Wed, Apr 23 | United Airlines$13614% OFF$158 $136
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MKE 6:43 AM4h 31m1 stopsDSM 11:14 AMMilwaukee - Des Moines | Fri, Mar 14 | Delta Air Lines$13714% OFF$158 $137
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MKE 10:15 AM4h 23m1 stopsDSM 2:38 PMMilwaukee - Des Moines | Thu, Apr 3 | United Airlines$1496% OFF$158 $149
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MKE 1:00 PM17h 25m1 stopsDSM Invalid DateMilwaukee - Des Moines | Sun, Mar 16 | Normal AirlineFind More FlightsFind More Flights
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Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.
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Frequently Asked Questions
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When are flight tickets from Milwaukee (MKE) to Des Moines (DSM) the cheapest?
Airlines adjust prices for flights from Milwaukee to Des Moines based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays. -
How much do flights from Milwaukee (MKE) to Des Moines (DSM) cost?
According to Trip.com's data, the lowest price is around $532.
How to find a cheap flight from Milwaukee to Des Moines
Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Milwaukee to Des Moines. Book your flights at the right time and save more.
Be flexible with your travel dates to get the cheapest Milwaukee to Des Moines ticket.
Tap "Date" in the flight search bar to browse the calendar and find airfare from Milwaukee to Des Moines for the next six months in 2025. If you're looking to fly within the next three months, the lowest fare is $106 for a one-way ticket on Tue, Mar 18.
Compare cheap Milwaukee to Des Moines flight deals from hundreds of airlines.
Our powerful search system compares prices from over 500 airlines. So you can find the cheapest flights from Milwaukee to Des Moines. The most affordable airline currently operating on this route is Delta Air Lines.
Set up a Price Alert to track fare drops.
Set up a Price Alert for your Milwaukee to Des Moines route to track ticket prices effortlessly—no need to check manually every day.
Don't miss out on cheap Milwaukee to Des Moines flight deals and promo codes.
Stay updated on the latest deals with Trip.com Deals and Promo Codes for cheap flights. Sign up for a free membership to unlock even more exclusive flight discounts.
Book early or wait unitl the last minute to fine the best fares.
It's always better to book early! Airlines typically release their lowest fares about a year before departure, so check as soon as flights become available. If you miss that window, you may still find great deals closer to your travel date.
Search for flights on the go.
For the best booking experience on the go, download Trip.com and search for cheap flights from Milwaukee to Des Moines to access exclusive deals just for you.
Flight Info | Milwaukee to Des Moines
| Cheapest nonstop flight price | $106 |
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| Off-season for travel | March |
| Peak season for travel | December |
| Flight distance | 499.31 km |
| Popular airline | American Airlines |
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