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Flights from Mobile to St. Louis

What to know about flights from Mobile to St. Louis?

The distance between Mobile and St. Louis is approximately 903.72 km. Based on Trip.com's data, travel demand peaks in July.

Cheapest one-way
$267
Delta Air Lines Delta Air Lines MOB-STL 7h 18m · 1 stop Thu, Oct 29
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Cheapest round-trip
$309
Delta Air Lines Delta Air Lines MOB-STL 4h 22m · 2 stops Sun, Nov 8 - Wed, Nov 11
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Recommended airlines
Delta Air Lines Delta Air Lines Cheapest · From $267 Delta Air Lines Delta Air Lines Most booked
When to travel
September
Cheapest
July
Peak season for travel
Route details
903.72 km
Flight distance

Explore the cheapest one-way and round-trip flights from Mobile to St. Louis over the next 90 days, with one-way fares from $267 and round-trip from $309. Based on Trip.com's latest 7-day flight data.

      • MOB 12:06 PM
        4h 22m
        1 stop
        STL 4:28 PM
        Mobile - St. Louis | Sun, Nov 8 | Delta Air Lines
        STL 12:29 PM
        4h 56m
        1 stop
        MOB 5:25 PM
        St. Louis - Mobile | Wed, Nov 11 | Delta Air Lines
        $309 $407
        24% off
        24% off
        $407 $309
      • MOB 6:17 PM
        5h 25m
        1 stop
        STL 11:42 PM
        Mobile - St. Louis | Fri, Oct 16 | American Airlines
        STL 5:40 AM
        5h 13m
        1 stop
        MOB 10:53 AM
        St. Louis - Mobile | Mon, Oct 19 | American Airlines
        $320 $407
        21% off
        21% off
        $407 $320
      • MOB 12:01 PM
        5h 34m
        1 stop
        STL 5:35 PM
        Mobile - St. Louis | Sun, Nov 8 | American Airlines
        STL 10:21 AM
        5h 11m
        1 stop
        MOB 3:32 PM
        St. Louis - Mobile | Wed, Nov 11 | American Airlines
        $320 $407
        21% off
        21% off
        $407 $320
      • MOB 6:30 PM
        5h 24m
        1 stop
        STL 11:54 PM
        Mobile - St. Louis | Fri, Oct 16 | Delta Air Lines
        STL 5:35 PM
        5h 42m
        1 stop
        MOB 11:17 PM
        St. Louis - Mobile | Tue, Oct 20 | Delta Air Lines
        $327
        20% off
        $407 $327
      • MOB 6:00 AM
        4h 51m
        1 stop
        STL 10:51 AM
        Mobile - St. Louis | Sat, Nov 7 | Delta Air Lines
        STL 10:00 AM
        5h 13m
        1 stop
        MOB 3:13 PM
        St. Louis - Mobile | Thu, Nov 12 | Delta Air Lines
        $330
        19% off
        $407 $330
      • MOB 6:12 PM
        5h 46m
        1 stop
        STL 11:58 PM
        Mobile - St. Louis | Fri, Nov 6 | American Airlines
        STL 5:00 AM
        5h 56m
        1 stop
        MOB 10:56 AM
        St. Louis - Mobile | Mon, Nov 9 | American Airlines
        $340
        16% off
        $407 $340
      • MOB 6:17 PM
        5h 25m
        1 stop
        STL 11:42 PM
        Mobile - St. Louis | Sat, Oct 31 | American Airlines
        STL 8:29 AM
        7h 3m
        1 stop
        MOB 3:32 PM
        St. Louis - Mobile | Mon, Nov 2 | American Airlines
        $340
        16% off
        $407 $340
      • MOB 5:03 PM
        6h 51m
        1 stop
        STL 11:54 PM
        Mobile - St. Louis | Fri, Nov 6 | Delta Air Lines
        STL 6:00 AM
        5h 17m
        1 stop
        MOB 11:17 AM
        St. Louis - Mobile | Mon, Nov 9 | Delta Air Lines
        $349
        14% off
        $407 $349
      • MOB 12:06 PM
        4h 22m
        1 stop
        STL 4:28 PM
        Mobile - St. Louis | Sat, Oct 31 | Delta Air Lines
        STL 10:25 AM
        5h 24m
        1 stop
        MOB 3:49 PM
        St. Louis - Mobile | Mon, Nov 2 | Delta Air Lines
        $349
        14% off
        $407 $349
      • MOB 5:51 PM
        6h 8m
        1 stop
        STL 11:59 PM
        Mobile - St. Louis | Sat, Oct 17 | American Airlines
        STL 3:30 PM
        5h 29m
        1 stop
        MOB 8:59 PM
        St. Louis - Mobile | Wed, Oct 21 | American Airlines
        $370
        9% off
        $407 $370
      • MOB 1:00 PM
        17h 25m
        1 stop
        STL 2:00 PM
        Mobile - St. Louis | Wed, Oct 14 | Normal Airline
        STL 3:00 PM
        6h
        Nonstop
        MOB 4:00 PM
        St. Louis - Mobile | Fri, Oct 16 | Normal Airline
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      • MOB 9:10 AM
        7h 18m
        1 stop
        STL 4:28 PM
        Mobile - St. Louis | Thu, Oct 29 | Delta Air Lines
        $267 $480
        44% off
        44% off
        $480 $267
      • MOB 9:11 AM
        6h 43m
        1 stop
        STL 3:54 PM
        Mobile - St. Louis | Tue, Oct 13 | Delta Air Lines
        $271 $480
        44% off
        44% off
        $480 $271
      • MOB 12:10 PM
        5h 30m
        1 stop
        STL 5:40 PM
        Mobile - St. Louis | Wed, Oct 14 | Delta Air Lines
        $273 $480
        43% off
        43% off
        $480 $273
      • MOB 5:24 PM
        5h 40m
        1 stop
        STL 11:04 PM
        Mobile - St. Louis | Wed, Oct 21 | American Airlines
        $275
        43% off
        $480 $275
      • MOB 5:51 PM
        6h 8m
        1 stop
        STL 11:59 PM
        Mobile - St. Louis | Sat, Oct 31 | American Airlines
        $275
        43% off
        $480 $275
      • MOB 6:00 PM
        5h 43m
        1 stop
        STL 11:43 PM
        Mobile - St. Louis | Tue, Oct 13 | American Airlines
        $275
        43% off
        $480 $275
      • MOB 8:28 AM
        4h 35m
        1 stop
        STL 1:03 PM
        Mobile - St. Louis | Wed, Oct 14 | American Airlines
        $275
        43% off
        $480 $275
      • MOB 5:51 PM
        6h 8m
        1 stop
        STL 11:59 PM
        Mobile - St. Louis | Tue, Nov 3 | American Airlines
        $276
        43% off
        $480 $276
      • MOB 5:51 PM
        6h 8m
        1 stop
        STL 11:59 PM
        Mobile - St. Louis | Fri, Nov 6 | American Airlines
        $276
        43% off
        $480 $276
      • MOB 6:17 PM
        5h 26m
        1 stop
        STL 11:43 PM
        Mobile - St. Louis | Mon, Oct 19 | American Airlines
        $436
        9% off
        $480 $436
      • MOB 1:00 PM
        17h 25m
        1 stop
        STL 2:00 PM
        Mobile - St. Louis | Wed, Oct 14 | Normal Airline
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Which airlines are the most popular for Mobile to St. Louis flights?

You can choose from 1 airlines that fly from Mobile to St. Louis, including Delta Air Lines, Delta Air Lines has lowest fares on this route.
Delta Air Lines logo Delta Air Lines
Airlines are determined based on actual purchased flight tickets from Mobile to St. Louis according to previous 12 months data from Trip.com.

Frequently Asked Questions

  • What are the cheapest flights from Mobile to St. Louis (MOB-STL)?

    Based on Trip.com data, Delta Air Lines offers one-way fares as low as $267 on Cheapest nonstop routes (e.g. MOB to STL on Thu, Oct 29), while Delta Air Lines offers Cheapest nonstop round-trips from $309 departing on Sun, Nov 8 and returning on Wed, Nov 11.
  • At the moment, several airlines serve connecting flights from Mobile to St. Louis, including: Delta Air Lines Selected airlines are based on historical data collected from flight bookings made by users on Trip.com within the last 90 days.
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Mobile to St. Louis is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • To find best deals on flights from Mobile to St. Louis, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Thu, Oct 29, with one-way flights priced at just $267.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is Delta Air Lines.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for St. Louis travel is around July.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Mobile to St. Louis is September, when demand for travel is lower.
  • After crunching the numbers on our October flight calendar, it's currently cheapest to fly from Mobile to St. Louis on October 15, 2026 with American Airlines, with prices starting at $320.
  • You can arrive at any of the following airports in St. Louis: St. Louis Lambert International Airport (STL), and St. Louis Downtown Airport (CPS). Flights from Mobile Regional Airport to St. Louis Lambert International Airport (MOB-STL) are by far the most popular option for this route.
  • The time difference between St. Louis and Mobile is 0m.
  • Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.
  • Based on Trip.com data for flights departing in the next 30 days, the average one-way fare from Mobile to St. Louis is $305. Fares vary by travel date, airline and availability.
  • Enter Mobile and St. Louis, choose your travel dates and passengers, then compare flights by price, duration and baggage. Select a fare, review the change and cancellation rules, enter traveler details and complete payment to receive your confirmation.

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Note: Prices shown on this page are estimated lowest price and include all taxes and fees found in the last 24 hours.

Book with no extra fees

Prices displayed in this page are all-inclusive prices (incl. taxes, fuel surcharge, civil aviation development fund, etc) with all fees confirmed before payment. Fees for luggage, meals, WLAN, or other additional services are also included as shown in the flight cards.

Real-time pricing updates

Prices, availability, and travel information on this page were updated within last 24 hours—even in real-time. The more popular the route, the more precise the data.

Change & Cancellation Policy

Trip.com displays flight cancellation and change policies for each flight ticket during the booking process, including fees and applicable conditions. Please check the following scenarios:
Voluntary cancellation/change:
To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy.
Cancellation/change due to a flight schedule change:
If the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.