Cheap Flights from Palermo to San Francisco from $627
Find the best flight deals from Palermo to San Francisco from $627
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Flights from Palermo to San Francisco
What to know about flights from Palermo to San Francisco?
The distance between Palermo and San Francisco is approximately 10,432.73 km. Based on Trip.com's data, travel demand peaks in July.
Cheapest one-way
$627
British Airways
PMO-SFO
35h 5m · 1 stop
Fri, Nov 20
Cheapest round-trip
$582
ITA Airways
PMO-SFO
31h 20m · 2 stops
Fri, Oct 23 - Fri, Oct 30
Recommended airlines
When to travel
September
Cheapest
July
Peak season for travel
Route details
10,432.73 km
Flight distance
How can I find cheap flights from Palermo to San Francisco?
Explore the cheapest one-way and round-trip flights from Palermo to San Francisco over the next 90 days, with one-way fares from $627 and round-trip from $582. Based on Trip.com's latest 7-day flight data.
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One way
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Round-trip
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PMO 2:55 PM31h 20m1 stopSFO 1:15 PMPalermo - San Francisco | Fri, Oct 23 | ITA Airways
SFO 4:05 PM19h 45m1 stopPMO 7:50 PMSan Francisco - Palermo | Fri, Oct 30 | ITA Airways
Price detailsDeparturePMO-FCOEconomy class
Included
In-flight meals are availableWi-Fi (additional charge)USB port and power outletFCO-SFOEconomy class
Included
In-flight meals are availableWi-Fi (additional charge)USB port and power outletReturnSFO-FCOEconomy class
Included
In-flight meals are availableWi-Fi (additional charge)USB port and power outletFCO-PMOEconomy class
Included
In-flight meals are availableWi-Fi (additional charge)USB port and power outlet$582 $89635% off35% off$896 $582 -
PMO 9:45 AM15h 45m1 stopSFO 4:30 PMPalermo - San Francisco | Fri, Nov 6 | Swiss Airlines
SFO 7:00 AM20h 20m1 stopPMO 12:20 PMSan Francisco - Palermo | Tue, Nov 10 | Lufthansa
Price detailsDeparturePMO-ZRHEconomy class
Included
Wi-Fi (additional charge)USB port and power outletZRH-SFOEconomy class
Included
In-flight meals are availableWi-Fi (additional charge)USB port and power outletReturnSFO-EWREconomy class
Included
Wi-Fi (additional charge)USB port and power outletEWR-PMOEconomy class
Included
In-flight meals are availableWi-Fi (additional charge)USB port and power outlet$587 $89634% off34% off$896 $587 -
PMO 6:10 AM16h1 stopSFO 1:10 PMPalermo - San Francisco | Sun, Nov 22 | ITA Airways
SFO 3:05 PM14h 15m1 stopPMO 2:20 PMSan Francisco - Palermo | Sun, Nov 29 | ITA Airways
Price detailsDeparturePMO-FCOEconomy class
Included
In-flight meals are availableFCO-SFOEconomy class
Included
In-flight meals are availableWi-Fi (additional charge)USB port and power outletReturnSFO-FCOEconomy class
Included
In-flight meals are availableWi-Fi (additional charge)USB port and power outletFCO-PMOEconomy class
Included
In-flight meals are availableWi-Fi (additional charge)USB port and power outlet$594 $89634% off34% off$896 $594
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PMO 7:25 PM29h 50m1 stopSFO 4:15 PMPalermo - San Francisco | Thu, Oct 15 | Swiss Airlines
SFO 2:25 PM19h 15m1 stopPMO 6:40 PMSan Francisco - Palermo | Wed, Oct 21 | Swiss Airlines
Price detailsDeparturePMO-ZRHEconomy class
Included
USB port and power outletZRH-SFOEconomy class
Included
In-flight meals are availableWi-Fi (additional charge)USB port and power outletReturnSFO-ZRHEconomy class
Included
In-flight meals are availableWi-Fi (additional charge)USB port and power outlet$59933% off$896 $599
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PMO 3:10 PM31h 5m1 stopSFO 1:15 PMPalermo - San Francisco | Fri, Oct 16 | ITA Airways
SFO 3:15 PM15h 10m1 stopPMO 3:25 PMSan Francisco - Palermo | Tue, Oct 20 | ITA Airways
Price detailsDeparturePMO-FCOEconomy class
Included
In-flight meals are availableWi-Fi (additional charge)USB port and power outletReturnSFO-FCOEconomy class
Included
In-flight meals are availableWi-Fi (additional charge)USB port and power outletFCO-PMOEconomy class
Included
In-flight meals are availableWi-Fi (additional charge)USB port and power outlet$59933% off$896 $599
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PMO 6:05 PM34h 30m1 stopSFO 7:35 PMPalermo - San Francisco | Fri, Nov 6 | Lufthansa
SFO 7:00 AM20h 20m1 stopPMO 12:20 PMSan Francisco - Palermo | Tue, Nov 10 | Lufthansa
Price detailsDeparturePMO-MUCEconomy class
Included
MUC-SFOEconomy class
Included
In-flight meals are availableWi-Fi (additional charge)USB port and power outletReturnSFO-EWREconomy class
Included
Wi-Fi (additional charge)USB port and power outletEWR-PMOEconomy class
Included
In-flight meals are availableWi-Fi (additional charge)USB port and power outlet$60532% off$896 $605
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PMO 9:45 AM15h 45m1 stopSFO 4:30 PMPalermo - San Francisco | Fri, Nov 27 | Swiss Airlines
SFO 6:45 PM31h 35m1 stopPMO 11:20 AMSan Francisco - Palermo | Fri, Dec 4 | Lufthansa
Price detailsDeparturePMO-ZRHEconomy class
Included
ZRH-SFOEconomy class
Included
In-flight meals are availableWi-Fi (additional charge)USB port and power outletReturnSFO-FRAEconomy class
Included
In-flight meals are availableWi-Fi (additional charge)USB port and power outlet$61731% off$896 $617
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PMO 6:10 AM16h1 stopSFO 1:10 PMPalermo - San Francisco | Fri, Nov 27 | ITA Airways
SFO 3:05 PM18h 15m1 stopPMO 6:20 PMSan Francisco - Palermo | Fri, Dec 4 | ITA Airways
Price detailsDeparturePMO-FCOEconomy class
Included
In-flight meals are availableFCO-SFOEconomy class
Included
In-flight meals are availableWi-Fi (additional charge)USB port and power outletReturnSFO-FCOEconomy class
Included
In-flight meals are availableWi-Fi (additional charge)USB port and power outletFCO-PMOEconomy class
Included
In-flight meals are available$64328% off$896 $643
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PMO 12:10 PM33h 25m1 stopSFO 12:35 PMPalermo - San Francisco | Fri, Nov 27 | Lufthansa
SFO 6:45 PM31h 35m1 stopPMO 11:20 AMSan Francisco - Palermo | Fri, Dec 4 | Lufthansa
Price detailsDeparturePMO-FRAEconomy class
Included
FRA-SFOEconomy class
Included
In-flight meals are availableWi-Fi (additional charge)USB port and power outletReturnSFO-FRAEconomy class
Included
In-flight meals are availableWi-Fi (additional charge)USB port and power outlet$64428% off$896 $644
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PMO 9:45 AM20h 37m1 stopSFO 9:22 PMPalermo - San Francisco | Fri, Oct 16 | Lufthansa
SFO 3:15 PM18h 5m1 stopPMO 6:20 PMSan Francisco - Palermo | Tue, Oct 20 | ITA Airways
Price detailsDeparturePMO-EWREconomy class
Included
In-flight meals are availableWi-Fi (additional charge)USB port and power outletReturnSFO-FCOEconomy class
Included
In-flight meals are availableWi-Fi (additional charge)USB port and power outletFCO-PMOEconomy class
Included
In-flight meals are available$65427% off$896 $654
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PMO 1:00 PM17h 25m1 stopSFO 2:00 PMPalermo - San Francisco | Fri, Oct 9 | Normal Airline
SFO 3:00 PM6hNonstopPMO 4:00 PMSan Francisco - Palermo | Sun, Oct 11 | Normal AirlineFind more flightsFind more flights
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PMO 12:50 PM35h 5m1 stopSFO 2:55 PMPalermo - San Francisco | Fri, Nov 20 | British Airways
Price detailsPMO-LHREconomy classWi-Fi (additional charge)USB port and power outletLHR-SFOEconomy classIn-flight meals are availableWi-Fi (additional charge)USB port and power outlet$627 $92132% off32% off$921 $627 -
PMO 6:30 AM23h 20m1 stopSFO 8:50 PMPalermo - San Francisco | Thu, Oct 15 | Transavia France
Price detailsPMO-ORYEconomy classORY-SFOEconomy classIn-flight meals are availableWi-Fi (additional charge)USB port and power outlet$634 $92131% off31% off$921 $634 -
PMO 6:30 AM23h 20m1 stopSFO 8:50 PMPalermo - San Francisco | Thu, Oct 22 | Transavia France
Price detailsPMO-ORYEconomy classORY-SFOEconomy classIn-flight meals are availableWi-Fi (additional charge)USB port and power outlet$639 $92131% off31% off$921 $639
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PMO 6:45 PM31h 45m1 stopSFO 5:30 PMPalermo - San Francisco | Mon, Nov 2 | Turkish Airlines
Price detailsPMO-ISTEconomy classIn-flight meals are availableWi-Fi (additional charge)USB port and power outletIST-SFOEconomy classIn-flight meals are availableWi-Fi (additional charge)USB port and power outlet$64130% off$921 $641 -
PMO 7:40 PM24h 5m1 stopSFO 10:45 AMPalermo - San Francisco | Thu, Oct 8 | Turkish Airlines
Price detailsPMO-ISTEconomy classIn-flight meals are availableUSB port and power outletIST-SFOEconomy classWi-Fi (additional charge)USB port and power outlet$64430% off$921 $644
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PMO 7:40 PM30h1 stopSFO 4:40 PMPalermo - San Francisco | Thu, Oct 15 | Turkish Airlines
Price detailsPMO-ISTEconomy classIn-flight meals are availableUSB port and power outletIST-SFOEconomy classIn-flight meals are availableWi-Fi (additional charge)USB port and power outlet$64730% off$921 $647
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PMO 6:55 PM29h1 stopSFO 3:55 PMPalermo - San Francisco | Sun, Oct 25 | British Airways
Price detailsPMO-LHREconomy classWi-Fi (additional charge)USB port and power outletLHR-SFOEconomy classIn-flight meals are availableWi-Fi (additional charge)USB port and power outlet$64830% off$921 $648
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PMO 11:35 AM17h 35m1 stopSFO 8:10 PMPalermo - San Francisco | Thu, Nov 12 | Transavia France
Price detailsPMO-ORYEconomy classORY-SFOEconomy classIn-flight meals are availableWi-Fi (additional charge)USB port and power outlet$65628% off$921 $656
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PMO 4:50 PM37h1 stopSFO 8:50 PMPalermo - San Francisco | Wed, Oct 14 | Transavia France
$66628% off$921 $666
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PMO 9:35 AM39h 55m1 stopSFO 4:30 PMPalermo - San Francisco | Sat, Nov 14 | Turkish Airlines
Price detailsPMO-ISTEconomy classIn-flight meals are availableUSB port and power outletIST-SFOEconomy classIn-flight meals are availableWi-Fi (additional charge)USB port and power outlet$67227% off$921 $672
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PMO 1:00 PM17h 25m1 stopSFO 2:00 PMPalermo - San Francisco | Fri, Oct 9 | Normal AirlineFind more flightsFind more flights
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Flight.News
A Heat Advisory is in effect for the San Francisco Bay Shoreline and surrounding areas until 10 PM PDT Thursday. Hot conditions will bring maximum temperatures ranging from the mid-90s to near 105, with limited overnight relief. This level of heat affects anyone lacking effective cooling or adequate hydration, posing potential impacts to health systems, infrastructure, and heat-sensitive industries.
Which airlines are the most popular for Palermo to San Francisco flights?
You can choose from 1 airlines that fly from Palermo to San Francisco, including ITA Airways, British Airways has lowest fares on this route.
ITA Airways
Airlines are determined based on actual purchased flight tickets from Palermo to San Francisco according to previous 12 months data from Trip.com.
Frequently Asked Questions
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What are the cheapest flights from Palermo to San Francisco (PMO-SFO)?
Based on Trip.com data, British Airways offers one-way fares as low as $627 on Cheapest nonstop routes (e.g. PMO to SFO on Fri, Nov 20), while ITA Airways offers Cheapest nonstop round-trips from $582 departing on Fri, Oct 23 and returning on Fri, Oct 30. -
Which airlines offer flights from Palermo to San Francisco?
At the moment, several airlines serve connecting flights from Palermo to San Francisco, including: ITA Airways Selected airlines are based on historical data collected from flight bookings made by users on Trip.com within the last 90 days. -
When is the best time to book flights from Palermo to San Francisco?
By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Palermo to San Francisco is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals. -
How can I find the best deals on flights from Palermo to San Francisco?
To find best deals on flights from Palermo to San Francisco, you can use various tools on Trip.com:
· Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Fri, Nov 20, with one-way flights priced at just $627.
· Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is British Airways.
· Set up price alerts to easily monitor ticket prices without having to check every day.
· Check Trip.com flight deals and promo codes frequently.
· Avoid peak season unless you book very early. It seems the peak season for San Francisco travel is around July.
· Get exclusive promo codes for Trip.com app users. -
When are flight tickets from Palermo (PMO) to San Francisco (SFO) the cheapest?
The cheapest months to fly from Palermo to San Francisco is September, when demand for travel is lower. -
Which upcoming date is cheapest to fly from Palermo to San Francisco on?
After crunching the numbers on our October flight calendar, it's currently cheapest to fly from Palermo to San Francisco on October 12, 2026 with British Airways, with prices starting at $551. -
Which airports can I fly into San Francisco from Palermo?
You can arrive at any of the following airports in San Francisco: San Francisco International Airport (SFO). Flights from Falcone-Borsellino International Airport to San Francisco International Airport (PMO-SFO) are by far the most popular option for this route. -
Is there any time difference between Palermo and San Francisco?
The time difference between San Francisco and Palermo is 9h. -
How do I change or cancel my ticket from Palermo to San Francisco?
Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages. -
What is the average cost of a one-way flight from Palermo to San Francisco?
Based on Trip.com data for flights departing in the next 30 days, the average one-way fare from Palermo to San Francisco is $1,387. Fares vary by travel date, airline and availability. -
How do I book flights from Palermo to San Francisco on Trip.com?
Enter Palermo and San Francisco, choose your travel dates and passengers, then compare flights by price, duration and baggage. Select a fare, review the change and cancellation rules, enter traveler details and complete payment to receive your confirmation.
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Note: Prices shown on this page are estimated lowest price and include all taxes and fees found in the last 24 hours.