Cheap flight from Portland to Des Moines from $170

Frequently Asked Questions

• Which airlines offer direct flights from Portland to Des Moines?

  At the moment, you can catch a nonstop flight from Portland to Des Moines with the following airlines, including: Allegiant Air Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.

• When is the best time to book flights from Portland to Des Moines?

  By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Portland to Des Moines is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.

• How many flights are there per week from Portland to Des Moines?

  Based on Trip.com data in the past 4 weeks, there is 1 flight per week flying from Portland to Des Moines. You can check the weekly schedule for popular airlines on this route below: Allegiant Air: -/-/-/-/-/-/- -- G4471 (09:46)

• When are flight tickets from Portland (PDX) to Des Moines (DSM) the cheapest?

  The cheapest months to fly from Portland to Des Moines is October, when demand for travel is lower.

• Which upcoming date is cheapest to fly from Portland to Des Moines on?

  After crunching the numbers on our November flight calendar, it's currently cheapest to fly from Portland to Des Moines on November 13, 2025 with Frontier Airlines, with prices starting at $169.

• Which airports can I fly to for Des Moines from Portland?

  You can land at any one of the following hubs in Des Moines, with Portland International Airport to Des Moines International Airport (PDX-DSM) is by far the most common option on this route: Des Moines International Airport (DSM).

• Is there any time difference between Portland and Des Moines?

  The time difference between Des Moines and Portland is 2h.

• How do I change or cancel my ticket from Portland to Des Moines?

  Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.