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Flights from Portland to Des Moines

Hi, I've summed up all the key info for Portland to Des Moines flights

Cheapest one-way

$ 148
American Airlines Fri, Oct 16

49% below next 30d avg. ($292)

Cheapest round-trip

$ 279
Delta Air Lines Tue, Sep 15

44% below next 30d avg. ($499)

When to travel

October Cheapest month
July Peak month

Recommended airlines

With a lowest one-way fare of $148 , travelers can expect an average price of $292 for upcoming trips, while round-trip tickets start at $279 . There are 1 flights weekly on this route. You can arrive at any of the following airports in Des Moines: Des Moines International Airport (DSM) . Flights from Portland International Airport to Des Moines International Airport (PDX-DSM) are by far the most popular option for this route. To secure the best rates, booking 40 days in advance is recommended, and the cheapest travel days are Tuesday, Wednesday, and Saturday .

Updated 4d ago · This content is an AI-powered summary based on Trip.com data. Prices and availability are subject to change. Please refer to actual prices, availability, and travel conditions.

Explore the cheapest one-way and round-trip flights from Portland to Des Moines over the next 90 days, with one-way fares from $148 and round-trip from $279. Based on Trip.com's latest 7-day flight data.

      • PDX 12:25 AM
        7h 52m
        1 stop
        DSM 10:17 AM
        Portland - Des Moines | Tue, Sep 15 | Delta Air Lines
        DSM 10:59 AM
        8h 32m
        1 stop
        PDX 5:31 PM
        Des Moines - Portland | Tue, Sep 22 | Delta Air Lines
        $279 $385
        28% off
        28% off
        $385 $279
      • PDX 6:00 AM
        6h 25m
        1 stop
        DSM 2:25 PM
        Portland - Des Moines | Tue, Oct 20 | Delta Air Lines
        DSM 7:51 PM
        5h 53m
        1 stop
        PDX 11:44 PM
        Des Moines - Portland | Thu, Oct 22 | Delta Air Lines
        $345 $385
        10% off
        10% off
        $385 $345
      • PDX 6:00 AM
        6h 6m
        1 stop
        DSM 2:06 PM
        Portland - Des Moines | Fri, Sep 25 | Delta Air Lines
        DSM 5:59 PM
        7h 11m
        1 stop
        PDX 11:10 PM
        Des Moines - Portland | Thu, Oct 1 | Delta Air Lines
        $345 $385
        10% off
        10% off
        $385 $345
      • PDX 1:44 PM
        5h 16m
        1 stop
        DSM 9:00 PM
        Portland - Des Moines | Fri, Oct 23 | Delta Air Lines
        DSM 7:51 PM
        5h 53m
        1 stop
        PDX 11:44 PM
        Des Moines - Portland | Fri, Oct 30 | Delta Air Lines
        $345
        10% off
        $385 $345
      • PDX 11:51 AM
        7h 9m
        1 stop
        DSM 9:00 PM
        Portland - Des Moines | Sun, Nov 1 | Delta Air Lines
        DSM 4:01 PM
        6h 1m
        1 stop
        PDX 8:02 PM
        Des Moines - Portland | Fri, Nov 6 | Delta Air Lines
        $349
        9% off
        $385 $349
      • PDX 6:30 AM
        6h 41m
        1 stop
        DSM 3:11 PM
        Portland - Des Moines | Tue, Oct 20 | American Airlines
        DSM 6:29 PM
        7h 26m
        1 stop
        PDX 11:55 PM
        Des Moines - Portland | Thu, Oct 22 | American Airlines
        $356
        8% off
        $385 $356
      • PDX 6:30 AM
        6h 41m
        1 stop
        DSM 3:11 PM
        Portland - Des Moines | Fri, Oct 23 | American Airlines
        DSM 4:12 PM
        6h 59m
        1 stop
        PDX 9:11 PM
        Des Moines - Portland | Fri, Oct 30 | American Airlines
        $356
        8% off
        $385 $356
      • PDX 5:10 AM
        6h 39m
        1 stop
        DSM 1:49 PM
        Portland - Des Moines | Sun, Nov 1 | American Airlines
        DSM 6:27 PM
        7h 16m
        1 stop
        PDX 11:43 PM
        Des Moines - Portland | Fri, Nov 6 | American Airlines
        $356
        8% off
        $385 $356
      • PDX 6:00 AM
        7h 10m
        1 stop
        DSM 3:10 PM
        Portland - Des Moines | Mon, Sep 14 | American Airlines
        DSM 5:56 PM
        8h 12m
        1 stop
        PDX 12:08 AM
        Des Moines - Portland | Sun, Sep 20 | American Airlines
        $357
        7% off
        $385 $357
      • PDX 6:00 AM
        6h 45m
        1 stop
        DSM 2:45 PM
        Portland - Des Moines | Mon, Oct 19 | Delta Air Lines
        DSM 6:55 AM
        7h 43m
        1 stop
        PDX 12:38 PM
        Des Moines - Portland | Tue, Oct 20 | Delta Air Lines
        $361
        6% off
        $385 $361
      • PDX 1:00 PM
        17h 25m
        1 stop
        DSM 2:00 PM
        Portland - Des Moines | Tue, Sep 15 | Normal Airline
        DSM 3:00 PM
        6h
        Nonstop
        PDX 4:00 PM
        Des Moines - Portland | Thu, Sep 17 | Normal Airline
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        Find more flights
      • PDX 10:55 PM
        8h 1m
        1 stop
        DSM 8:56 AM
        Portland - Des Moines | Fri, Oct 16 | American Airlines
        $148 $493
        70% off
        70% off
        $493 $148
      • PDX 6:00 AM
        6h 25m
        1 stop
        DSM 2:25 PM
        Portland - Des Moines | Sun, Oct 18 | Delta Air Lines
        $174 $493
        65% off
        65% off
        $493 $174
      • PDX 6:00 AM
        6h 25m
        1 stop
        DSM 2:25 PM
        Portland - Des Moines | Thu, Nov 5 | Delta Air Lines
        $174 $493
        65% off
        65% off
        $493 $174
      • PDX 6:00 AM
        6h 25m
        1 stop
        DSM 2:25 PM
        Portland - Des Moines | Sun, Nov 8 | Delta Air Lines
        $174
        65% off
        $493 $174
      • PDX 12:45 AM
        7h 34m
        1 stop
        DSM 10:19 AM
        Portland - Des Moines | Tue, Nov 10 | Delta Air Lines
        $174
        65% off
        $493 $174
      • PDX 11:52 AM
        5h 23m
        1 stop
        DSM 7:15 PM
        Portland - Des Moines | Wed, Nov 11 | Delta Air Lines
        $174
        65% off
        $493 $174
      • PDX 6:00 AM
        6h 25m
        1 stop
        DSM 2:25 PM
        Portland - Des Moines | Wed, Oct 14 | Delta Air Lines
        $174
        65% off
        $493 $174
      • PDX 11:49 PM
        7h 26m
        1 stop
        DSM 9:15 AM
        Portland - Des Moines | Wed, Oct 14 | American Airlines
        $178
        64% off
        $493 $178
      • PDX 5:20 AM
        7h 51m
        1 stop
        DSM 3:11 PM
        Portland - Des Moines | Sun, Oct 18 | American Airlines
        $178
        64% off
        $493 $178
      • PDX 11:08 PM
        7h 31m
        1 stop
        DSM 8:39 AM
        Portland - Des Moines | Tue, Sep 15 | American Airlines
        $463
        6% off
        $493 $463
      • PDX 1:00 PM
        17h 25m
        1 stop
        DSM 2:00 PM
        Portland - Des Moines | Tue, Sep 15 | Normal Airline
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        Find more flights

Which airlines are the most popular for Portland to Des Moines flights?

You can choose from 1 airlines that fly from Portland to Des Moines, including American Airlines, American Airlines has lowest fares on this route.
American Airlines logo American Airlines
Airlines are determined based on actual purchased flight tickets from Portland to Des Moines according to previous 12 months data from Trip.com.

Flight Info | Portland to Des Moines

The distance between Portland and Des Moines is approximately 2,361.55 km. Based on Trip.com's data travel demand peaks in July. The off-season for travel is October.

Cheapest one-way flight price $148
Cheapest round-trip ticket price $279
Off-season for travel October
Peak season for travel July
Flight distance 2,361.55 km
Popular airline American Airlines
Flight statistics for the Portland–Des Moines route are based on aggregated booking data from Trip.com over the past 12 months.

Frequently Asked Questions

  • What are the cheapest flights from Portland to Des Moines (PDX-DSM)?

    Based on Trip.com data, American Airlines offers one-way fares as low as $148 on Cheapest nonstop routes (e.g. PDX to DSM on Fri, Oct 16), while Delta Air Lines offers Cheapest nonstop round-trips from $279 departing on Tue, Sep 15 and returning on Tue, Sep 22.
  • At the moment, you can catch a nonstop flight from Portland to Des Moines with the following airlines, including: Allegiant Air Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Portland to Des Moines is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • Based on Trip.com data in the past 4 weeks, there is 1 flight per week flying from Portland to Des Moines. You can check the weekly schedule for popular airlines on this route below: Allegiant Air: -/-/-/-/-/-/- -- G4461 (12:25)
  • To find best deals on flights from Portland to Des Moines, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Fri, Oct 16, with one-way flights priced at just $148.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is American Airlines.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Des Moines travel is around July.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Portland to Des Moines is October, when demand for travel is lower.
  • After crunching the numbers on our September flight calendar, it's currently cheapest to fly from Portland to Des Moines on September 14, 2026 with American Airlines, with prices starting at $179.
  • You can arrive at any of the following airports in Des Moines: Des Moines International Airport (DSM). Flights from Portland International Airport to Des Moines International Airport (PDX-DSM) are by far the most popular option for this route.
  • The time difference between Des Moines and Portland is 2h.
  • Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.
  • Based on Trip.com data for flights departing in the next 30 days, the average one-way fare from Portland to Des Moines is $292. Fares vary by travel date, airline and availability.
  • Based on Trip.com data for travel in the next 30 days, the average round-trip fare from Portland to Des Moines is $499. The final price depends on the outbound and return dates, airline and fare conditions.
  • Enter Portland and Des Moines, choose your travel dates and passengers, then compare flights by price, duration and baggage. Select a fare, review the change and cancellation rules, enter traveler details and complete payment to receive your confirmation.

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Note: Prices shown on this page are estimated lowest price and include all taxes and fees found in the last 24 hours.

Book with no extra fees

Prices displayed in this page are all-inclusive prices (incl. taxes, fuel surcharge, civil aviation development fund, etc) with all fees confirmed before payment. Fees for luggage, meals, WLAN, or other additional services are also included as shown in the flight cards.

Real-time pricing updates

Prices, availability, and travel information on this page were updated within last 24 hours—even in real-time. The more popular the route, the more precise the data.

Change & Cancellation Policy

Trip.com displays flight cancellation and change policies for each flight ticket during the booking process, including fees and applicable conditions. Please check the following scenarios:
Voluntary cancellation/change:
To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy.
Cancellation/change due to a flight schedule change:
If the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.