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Flights from Portland to St. Louis

Book direct flights from Portland to St. Louis: One way flights from $145, round trip flights from $290. Find flight deals for the next 3 months below.

      • Cheapest nonstop
        PDX 11:16 AM
        3h 54m
        Nonstop
        STL 5:10 PM
        Portland - St. Louis | Wed, Aug 19 | Alaska Airlines
        STL 6:08 PM
        4h 12m
        Nonstop
        PDX 8:20 PM
        St. Louis - Portland | Wed, Aug 26 | Alaska Airlines
        $290 $357
        19% off
        19% off
        $357 $290
      • PDX 11:16 AM
        3h 54m
        Nonstop
        STL 5:10 PM
        Portland - St. Louis | Sat, Aug 22 | Alaska Airlines
        STL 6:08 PM
        4h 12m
        Nonstop
        PDX 8:20 PM
        St. Louis - Portland | Sat, Aug 29 | Alaska Airlines
        $314 $357
        12% off
        12% off
        $357 $314
      • PDX 10:55 PM
        8h 59m
        1 stop
        STL 9:54 AM
        Portland - St. Louis | Thu, Aug 13 | Delta Air Lines
        STL 7:45 PM
        5h 54m
        1 stop
        PDX 11:39 PM
        St. Louis - Portland | Mon, Aug 17 | Delta Air Lines
        $197 $357
        45% off
        45% off
        $357 $197
      • PDX 2:08 PM
        7h 13m
        1 stop
        STL 11:21 PM
        Portland - St. Louis | Tue, Sep 1 | Delta Air Lines
        STL 11:21 AM
        8h 10m
        1 stop
        PDX 5:31 PM
        St. Louis - Portland | Tue, Sep 8 | Delta Air Lines
        $197
        45% off
        $357 $197
      • PDX 12:35 AM
        7h 48m
        1 stop
        STL 10:23 AM
        Portland - St. Louis | Sat, Aug 22 | Delta Air Lines
        STL 3:44 PM
        8h
        1 stop
        PDX 9:44 PM
        St. Louis - Portland | Sat, Aug 29 | Delta Air Lines
        $200
        44% off
        $357 $200
      • PDX 12:35 AM
        7h 48m
        1 stop
        STL 10:23 AM
        Portland - St. Louis | Sat, Aug 29 | Delta Air Lines
        STL 3:44 PM
        8h
        1 stop
        PDX 9:44 PM
        St. Louis - Portland | Sat, Aug 29 | Delta Air Lines
        $209
        41% off
        $357 $209
      • PDX 11:34 PM
        6h 49m
        1 stop
        STL 8:23 AM
        Portland - St. Louis | Tue, Aug 25 | American Airlines
        STL 5:42 AM
        7h 12m
        1 stop
        PDX 10:54 AM
        St. Louis - Portland | Sat, Aug 29 | American Airlines
        $241
        32% off
        $357 $241
      • PDX 3:00 PM
        6h 26m
        1 stop
        STL 11:26 PM
        Portland - St. Louis | Thu, Sep 3 | Delta Air Lines
        STL 5:00 PM
        7h 31m
        1 stop
        PDX 10:31 PM
        St. Louis - Portland | Tue, Sep 8 | Delta Air Lines
        $253
        28% off
        $357 $253
      • PDX 6:17 PM
        21h 33m
        1 stop
        STL 5:50 PM
        Portland - St. Louis | Mon, Aug 31 | Frontier Airlines
        STL 6:45 PM
        20h 7m
        1 stop
        PDX 12:52 PM
        St. Louis - Portland | Wed, Sep 2 | Frontier Airlines
        $256
        28% off
        $357 $256
      • PDX 6:49 PM
        21h 26m
        1 stop
        STL 6:15 PM
        Portland - St. Louis | Sun, Aug 16 | Frontier Airlines
        STL 7:58 PM
        23h 13m
        1 stop
        PDX 5:11 PM
        St. Louis - Portland | Sun, Aug 23 | Frontier Airlines
        $256
        28% off
        $357 $256
      • PDX 6:49 PM
        21h 26m
        1 stop
        STL 6:15 PM
        Portland - St. Louis | Thu, Aug 13 | Frontier Airlines
        STL 7:58 PM
        23h 13m
        1 stop
        PDX 5:11 PM
        St. Louis - Portland | Thu, Aug 20 | Frontier Airlines
        $256
        28% off
        $357 $256
      • PDX 5:56 PM
        23h 17m
        1 stop
        STL 7:13 PM
        Portland - St. Louis | Wed, Aug 19 | Frontier Airlines
        STL 6:45 PM
        20h 7m
        1 stop
        PDX 12:52 PM
        St. Louis - Portland | Wed, Aug 26 | Frontier Airlines
        $256
        28% off
        $357 $256
      • PDX 1:00 PM
        17h 25m
        1 stop
        STL 2:00 PM
        Portland - St. Louis | Wed, Jul 22 | Normal Airline
        STL 3:00 PM
        6h
        Nonstop
        PDX 4:00 PM
        St. Louis - Portland | Fri, Jul 24 | Normal Airline
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      • Cheapest nonstop
        PDX 11:16 AM
        3h 54m
        Nonstop
        STL 5:10 PM
        Portland - St. Louis | Wed, Aug 19 | Alaska Airlines
        $145 $195
        26% off
        26% off
        $195 $145
      • PDX 11:16 AM
        3h 54m
        Nonstop
        STL 5:10 PM
        Portland - St. Louis | Tue, Aug 25 | Alaska Airlines
        $171 $195
        12% off
        12% off
        $195 $171
      • PDX 12:35 AM
        7h 48m
        1 stop
        STL 10:23 AM
        Portland - St. Louis | Sat, Aug 15 | Delta Air Lines
        $107 $195
        45% off
        45% off
        $195 $107
      • PDX 2:08 PM
        7h 13m
        1 stop
        STL 11:21 PM
        Portland - St. Louis | Wed, Aug 26 | Delta Air Lines
        $107
        45% off
        $195 $107
      • PDX 3:00 PM
        6h 26m
        1 stop
        STL 11:26 PM
        Portland - St. Louis | Thu, Aug 27 | Delta Air Lines
        $124
        36% off
        $195 $124
      • PDX 6:49 PM
        21h 26m
        1 stop
        STL 6:15 PM
        Portland - St. Louis | Sun, Aug 16 | Frontier Airlines
        $126
        35% off
        $195 $126
      • PDX 6:49 PM
        21h 26m
        1 stop
        STL 6:15 PM
        Portland - St. Louis | Thu, Aug 13 | Frontier Airlines
        $127
        35% off
        $195 $127
      • PDX 5:49 PM
        22h 26m
        1 stop
        STL 6:15 PM
        Portland - St. Louis | Fri, Aug 14 | Frontier Airlines
        $127
        35% off
        $195 $127
      • PDX 5:56 PM
        23h 17m
        1 stop
        STL 7:13 PM
        Portland - St. Louis | Wed, Aug 19 | Frontier Airlines
        $127
        35% off
        $195 $127
      • PDX 5:49 PM
        22h 26m
        1 stop
        STL 6:15 PM
        Portland - St. Louis | Fri, Aug 7 | Frontier Airlines
        $128
        34% off
        $195 $128
      • PDX 1:47 PM
        26h 3m
        1 stop
        STL 5:50 PM
        Portland - St. Louis | Thu, Aug 20 | Frontier Airlines
        $129
        34% off
        $195 $129
      • PDX 5:21 PM
        24h 2m
        1 stop
        STL 7:23 PM
        Portland - St. Louis | Wed, Aug 5 | Frontier Airlines
        $151
        23% off
        $195 $151
      • PDX 1:00 PM
        17h 25m
        1 stop
        STL 2:00 PM
        Portland - St. Louis | Wed, Jul 22 | Normal Airline
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Find cheap airlines flights from Portland to St. Louis

You can choose from 3 airlines that fly from Portland to St. Louis, including Alaska Airlines, Frontier Airlines, and Delta Air Lines. Alaska Airlines has lowest fares on this route.
Alaska Airlines logo Alaska Airlines
Frontier Airlines logo Frontier Airlines
Delta Air Lines logo Delta Air Lines
Airlines are determined based on actual purchased flight tickets from Portland to St. Louis according to previous 12 months data from Trip.com.

Flight Info | Portland to St. Louis

The distance between Portland and St. Louis is approximately 2,763.15 km. It takes around 3 hours 44 minutes on average to fly from Portland to St. Louis. Based on Trip.com's data travel demand peaks in July. The off-season for travel is October.

Cheapest one-way flight price$107
Cheapest round-trip ticket price$197
Off-season for travelOctober
Peak season for travelJuly
Flight distance2,763.15 km
Average flight time3 hours 44 minutes
Popular airlineAlaska Airlines
Flight statistics for the Portland–St. Louis route are based on aggregated booking data from Trip.com over the past 12 months.

Frequently Asked Questions

  • What are the cheapest flights from Portland to St. Louis (PDX-STL)?

    Based on Trip.com data, Delta Air Lines offers one-way fares as low as $107 on Cheapest nonstop routes (e.g. PDX to STL on Sat, Aug 15), while Delta Air Lines offers Cheapest nonstop round-trips from $197 departing on Thu, Aug 13 and returning on Mon, Aug 17.
  • At the moment, you can catch a nonstop flight from Portland to St. Louis with the following airlines, including: Alaska Airlines Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.
  • It takes around 3 hours 44 minutes to fly from Portland (PDX) to St. Louis (STL).
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Portland to St. Louis is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • Based on Trip.com data in the past 4 weeks, there is 5 flight per week flying from Portland to St. Louis. You can check the weekly schedule for popular airlines on this route below: Alaska Airlines: S/M/T/W/T/F/S -- AS1635 (10:54)
  • To find best deals on flights from Portland to St. Louis, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Sat, Aug 15, with one-way flights priced at just $107.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is Alaska Airlines.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for St. Louis travel is around July.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Portland to St. Louis is October, when demand for travel is lower.
  • After crunching the numbers on our July flight calendar, it's currently cheapest to fly from Portland to St. Louis on July 29, 2026 with Frontier Airlines, with prices starting at $261.
  • You can land at any one of the following hubs in St. Louis, with Portland International Airport to St. Louis Lambert International Airport (PDX-STL) is by far the most common option on this route: St. Louis Lambert International Airport (STL) St. Louis Downtown Airport (CPS).
  • The time difference between St. Louis and Portland is 2h.
  • Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

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Note: Prices shown on this page are estimated lowest price and include all taxes and fees found in the last 24 hours.

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Prices displayed in this page are all-inclusive prices (incl. taxes, fuel surcharge, civil aviation development fund, etc) with all fees confirmed before payment. Fees for luggage, meals, WLAN, or other additional services are also included as shown in the flight cards.

Real-time pricing updates

Prices, availability, and travel information on this page were updated within last 24 hours—even in real-time. The more popular the route, the more precise the data.

Change & Cancellation Policy

Trip.com displays flight cancellation and change policies for each flight ticket during the booking process, including fees and applicable conditions. Please check the following scenarios:
Voluntary cancellation/change:
To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy.
Cancellation/change due to a flight schedule change:
If the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.