$59 Find Cheap Flights from San Diego to Des Moines

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Find cheap flights from San Diego to Des Moines starting at $59.

Book one-way or return flights from San Diego to Des Moines from as little as $59. Choose from the popular airlines below and book your flight today!

One way
Round-trip

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Searching for the best last minute flight from San Diego to Des Moines? Find one-way or return flights that are affordable and fit your itinerary.

Trip.com monitors the ticket fares of flights from San Diego to Des Moines. Stay updated on price trends and snag the best deals for your upcoming trip.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Find cheap airlines flights from San Diego to Des Moines

View airlines operating flights from San Diego to Des Moines. Compare prices, find the option that best suits your travel needs, and enjoy a comfortable journey with a trusted airline.

Frontier Airlines

From $59

United Airlines

From $130

Spirit Airlines

From $140

American Airlines

From $152

Delta Air Lines

From $162

Sun Country Airlines

From $173

Southwest Airlines

From $236

Alaska Airlines

From $374

ANA airlines

Find more flights and airlines

Find cheap flights from San Diego to Des Moines by different airports

Discover different routes, airlines, and transfers and find the best alternative flights for your journey from San Diego to Des Moines.

Cheapest
SAN
10:02
26h 23m
1 transfer
DSM
14:25
San Diego International Airport - Des Moines International Airport
Tue, May 7Frontier Airlines
$59
SAN
10:02
26h 23m
1 transfer
DSM
14:25
San Diego International Airport - Des Moines International Airport
Tue, May 7Frontier Airlines
$59
Find More Flights

Frequently Asked Questions

When are flight tickets from San Diego (SAN) to Des Moines (DSM) the cheapest?
Airlines adjust prices for flights from San Diego to Des Moines based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.
How much do flights from San Diego (SAN) to Des Moines (DSM) cost?
According to Trip.com's data, the lowest price is around $390.
How long does it take to fly from San Diego (SAN) to Des Moines (DSM) and what is the distance?
It takes around 5 hours 2 minutes to fly from San Diego (SAN) to Des Moines (DSM).
What are the most popular airlines that fly from San Diego (SAN) to Des Moines (DSM)?
Airlines with flights from San Diego (SAN) to Des Moines (DSM): Frontier Airlines and Southwest Airlines.

How to find a cheap flight from San Diego to Des Moines

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from San Diego to Des Moines. Book your flights at the right time and save more.

Book Early

Once prices are gone, they're gone. Lock in deals while you can!

Compare Flight Prices

Compare prices on travel agency and airline websites.

Look Out for Deals

Check airline and travel agency websites for latest flight deals

Check One-way Fares

Buying two cheap one-way flights can sometimes be a better deal than a round-trip.

Try Different Dates

Flying during the week, early in the morning, or late at night can help save money.

Use the Trip.com App

Save up to £10 per person when booking your flights on Trip.com

San Diego to Des Moines Flight Information

Cheapest nonstop flight price	$58
Cheapest round-trip ticket price	$254
Off-season for travel	April
Peak season for travel	July
Flight distance	2,293.72km
Average flight time	5 hours 2 minutes
Popular airline	American Airlines