Cheap flight from San Diego to Santiago from $725
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Flights from San Diego to Santiago
Find cheap airlines flights from San Diego to Santiago
Compare prices, find the option that best suits your travel needs, and enjoy a comfortable journey with a trusted airline.
Cheap flight deals from San Diego to Santiago
We've found these cheap flights for you. You can book one-way or round-trip flight tickets.
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SAN 9:03 PM19h 21m1 stopsSCL 7:24 PMSan Diego - Santiago | Mon, Jul 7 | Copa Airlines
SCL 12:18 AM20h 26m1 stopsSAN 5:44 PMSantiago - San Diego | Mon, Jul 14 | Copa Airlines$725 $1,46651% OFF51% OFF$1,466 $725 -
SAN 12:18 PM15h 42m1 stopsSCL 7:00 AMSan Diego - Santiago | Thu, Jun 26 | LATAM Airlines
SCL 8:40 PM15h 59m1 stopsSAN 9:39 AMSantiago - San Diego | Thu, Jul 3 | LATAM Airlines$1,058 $1,46628% OFF28% OFF$1,466 $1,058 -
SAN 6:15 AM20h 45m1 stopsSCL 6:00 AMSan Diego - Santiago | Wed, Jun 18 | Delta Air Lines
SCL 10:45 PM23h 9m1 stopsSAN 6:54 PMSantiago - San Diego | Wed, Jun 25 | LATAM Airlines$1,096 $1,46625% OFF25% OFF$1,466 $1,096 -
SAN 6:15 AM20h 45m1 stopsSCL 6:00 AMSan Diego - Santiago | Wed, Jun 18 | LATAM Airlines
SCL 10:45 PM23h 9m1 stopsSAN 6:54 PMSantiago - San Diego | Wed, Jun 25 | LATAM Airlines$1,10924% OFF$1,466 $1,109
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SAN 9:50 PM29h 55m1 stopsSCL 6:45 AMSan Diego - Santiago | Wed, Jun 18 | Alaska Airlines
SCL 10:45 PM19h 37m1 stopsSAN 3:22 PMSantiago - San Diego | Wed, Jun 25 | LATAM Airlines$1,11324% OFF$1,466 $1,113 -
SAN 6:20 AM20h 40m1 stopsSCL 6:00 AMSan Diego - Santiago | Fri, Jul 18 | Delta Air Lines
SCL 10:45 PM20h 36m1 stopsSAN 4:21 PMSantiago - San Diego | Fri, Jul 25 | Delta Air Lines$1,11624% OFF$1,466 $1,116
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SAN 10:00 AM17h1 stopsSCL 6:00 AMSan Diego - Santiago | Mon, Jun 16 | LATAM Airlines
SCL 10:45 PM19h 37m1 stopsSAN 3:22 PMSantiago - San Diego | Mon, Jun 23 | LATAM Airlines$1,14122% OFF$1,466 $1,141
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SAN 7:35 PM31h 25m1 stopsSCL 6:00 AMSan Diego - Santiago | Tue, Jul 8 | LATAM Airlines
SCL 10:45 PM23h 9m1 stopsSAN 6:54 PMSantiago - San Diego | Tue, Jul 15 | LATAM Airlines$1,14222% OFF$1,466 $1,142
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SAN 7:35 PM31h 25m1 stopsSCL 6:00 AMSan Diego - Santiago | Mon, Jul 14 | LATAM Airlines
SCL 10:45 PM19h 34m1 stopsSAN 3:19 PMSantiago - San Diego | Mon, Jul 21 | LATAM Airlines$1,14222% OFF$1,466 $1,142
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SAN 11:04 AM16h 56m1 stopsSCL 7:00 AMSan Diego - Santiago | Sat, Jun 28 | Delta Air Lines
SCL 8:40 PM15h 59m1 stopsSAN 9:39 AMSantiago - San Diego | Sat, Jul 5 | Delta Air Lines$1,14322% OFF$1,466 $1,143
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SAN 1:00 PM17h 25m1 stopsSCL Invalid DateSan Diego - Santiago | Sun, Jun 15 | Normal Airline
SCL 3:00 PM6hNonstopSAN 4:00 PMSantiago - San Diego | Tue, Jun 17 | Normal AirlineFind More FlightsFind More Flights
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SAN 6:15 AM20h 45m1 stopsSCL 6:00 AMSan Diego - Santiago | Tue, Jun 17 | Delta Air Lines$544 $77330% OFF30% OFF$773 $544
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SAN 6:15 AM20h 45m1 stopsSCL 6:00 AMSan Diego - Santiago | Tue, Aug 5 | Delta Air Lines$558 $77328% OFF28% OFF$773 $558
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SAN 12:07 PM15h 53m1 stopsSCL 7:00 AMSan Diego - Santiago | Tue, Aug 5 | LATAM Airlines$558 $77328% OFF28% OFF$773 $558
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SAN 6:20 AM20h 40m1 stopsSCL 6:00 AMSan Diego - Santiago | Wed, Jul 16 | LATAM Airlines$56227% OFF$773 $562
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SAN 6:15 AM21h 45m1 stopsSCL 7:00 AMSan Diego - Santiago | Thu, Jul 17 | LATAM Airlines$56827% OFF$773 $568
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SAN 3:59 PM35h 1m1 stopsSCL 6:00 AMSan Diego - Santiago | Tue, Jul 8 | Delta Air Lines$57825% OFF$773 $578
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SAN 6:15 AM20h 45m1 stopsSCL 6:00 AMSan Diego - Santiago | Tue, Jun 17 | LATAM Airlines$59823% OFF$773 $598
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SAN 6:15 AM20h 45m1 stopsSCL 6:00 AMSan Diego - Santiago | Wed, Jun 18 | LATAM Airlines$59823% OFF$773 $598
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SAN 9:00 AM18h 45m1 stopsSCL 6:45 AMSan Diego - Santiago | Thu, Jul 24 | Alaska Airlines$60122% OFF$773 $601
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SAN 8:00 AM20h1 stopsSCL 7:00 AMSan Diego - Santiago | Tue, Jul 8 | LATAM Airlines$60322% OFF$773 $603
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SAN 1:00 PM17h 25m1 stopsSCL Invalid DateSan Diego - Santiago | Sun, Jun 15 | Normal AirlineFind More FlightsFind More Flights
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Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.
Flight Info | San Diego to Santiago
| Cheapest one-way flight price | $543 |
|---|---|
| Off-season for travel | March |
| Peak season for travel | March |
| Flight distance | 8,810.71 km |
| Popular airline | Alaska Airlines |
When is the cheapest time to fly from San Diego to Santiago?
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Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.
Frequently Asked Questions
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When are flight tickets from San Diego (SAN) to Santiago (SCL) the cheapest?
Airlines adjust prices for flights from San Diego to Santiago based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays. -
How much do flights from San Diego (SAN) to Santiago (SCL) cost?
According to Trip.com's data, the lowest price is around $1,087.
How to find a cheap flight from San Diego to Santiago
Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from San Diego to Santiago. Book your flights at the right time and save more.
Be flexible with your travel dates to get the cheapest San Diego to Santiago ticket.
Tap "Date" in the flight search bar to browse the calendar and find airfare from San Diego to Santiago for the next six months in 2025. If you're looking to fly within the next three months, the lowest fare is $544 for a one-way ticket on Tue, Jun 17.
Compare cheap San Diego to Santiago flight deals from hundreds of airlines.
Our powerful search system compares prices from over 500 airlines. So you can find the cheapest flights from San Diego to Santiago. The most affordable airline currently operating on this route is Delta Air Lines.
Set up a Price Alert to track fare drops.
Set up a Price Alert for your San Diego to Santiago route to track ticket prices effortlessly—no need to check manually every day.
Don't miss out on cheap San Diego to Santiago flight deals and promo codes.
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Book early or wait unitl the last minute to fine the best fares.
It's always better to book early! Airlines typically release their lowest fares about a year before departure, so check as soon as flights become available. If you miss that window, you may still find great deals closer to your travel date.
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For the best booking experience on the go, download Trip.com and search for cheap flights from San Diego to Santiago to access exclusive deals just for you.
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