Cheap Flights from San Francisco to Panama City from $437

Frequently Asked Questions

• What are the cheapest flights from San Francisco to Panama City (SFO-PTY)?

  Based on Trip.com data, Aeromexico offers one-way fares as low as $437 on Cheapest nonstop routes (e.g. SFO to PTY on Tue, Aug 25), while Delta Air Lines offers Cheapest nonstop round-trips from $762 departing on Mon, Sep 14 and returning on Fri, Sep 18.

• Which airlines offer direct flights from San Francisco to Panama City?

  At the moment, you can catch a nonstop flight from San Francisco to Panama City with the following airlines, including: Copa Airlines Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.

• How long does it take to fly from San Francisco (SFO) to Panama City (PTY) and what is the distance?

  It takes around 7 hours 1 minute to fly from San Francisco (SFO) to Panama City (PTY).

• When is the best time to book flights from San Francisco to Panama City?

  By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from San Francisco to Panama City is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.

• How many flights are there per week from San Francisco to Panama City?

  Based on Trip.com data in the past 4 weeks, there is 17 flight per week flying from San Francisco to Panama City. You can check the weekly schedule for popular airlines on this route below: Copa Airlines: S/M/T/W/T/F/S -- CM383 (01:16) United Airlines: S/M/T/W/T/F/S -- UA7132 (01:16)

• How can I find the best deals on flights from San Francisco to Panama City?

  To find best deals on flights from San Francisco to Panama City, you can use various tools on Trip.com:
  · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Tue, Aug 25, with one-way flights priced at just $437.
  · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is Copa Airlines.
  · Set up price alerts to easily monitor ticket prices without having to check every day.
  · Check Trip.com flight deals and promo codes frequently.
  · Avoid peak season unless you book very early. It seems the peak season for Panama City travel is around January.
  · Get exclusive promo codes for Trip.com app users.

• When are flight tickets from San Francisco (SFO) to Panama City (PTY) the cheapest?

  The cheapest months to fly from San Francisco to Panama City is September, when demand for travel is lower.

• Which upcoming date is cheapest to fly from San Francisco to Panama City on?

  After crunching the numbers on our August flight calendar, it's currently cheapest to fly from San Francisco to Panama City on August 17, 2026 with avianca, with prices starting at $743.

• Which airports can I fly to for Panama City from San Francisco?

  You can land at any one of the following hubs in Panama City, with San Francisco International Airport to Tocumen International Airport (SFO-PTY) is by far the most common option on this route: Tocumen International Airport (PTY) Marcos A. Gelabert International Airport (PAC).

• Is there any time difference between San Francisco and Panama City?

  The time difference between Panama City and San Francisco is 3h.

• How do I change or cancel my ticket from San Francisco to Panama City?

  Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

• What is the average cost of a one-way flight from San Francisco to Panama City?

  Based on Trip.com data for flights departing in the next 30 days, the average one-way fare from San Francisco to Panama City is $795. Fares vary by travel date, airline and availability.

• What is the average cost of a round-trip flight from San Francisco to Panama City?

  Based on Trip.com data for travel in the next 30 days, the average round-trip fare from San Francisco to Panama City is $889. The final price depends on the outbound and return dates, airline and fare conditions.

• How do I book flights from San Francisco to Panama City on Trip.com?

  Enter San Francisco and Panama City, choose your travel dates and passengers, then compare flights by price, duration and baggage. Select a fare, review the change and cancellation rules, enter traveler details and complete payment to receive your confirmation.