Cheap flight from San Francisco to Santiago from $671
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Flights from San Francisco to Santiago
Find cheap airlines flights from San Francisco to Santiago
Compare prices, find the option that best suits your travel needs, and enjoy a comfortable journey with a trusted airline.
Cheap flight deals from San Francisco to Santiago
We've found these cheap flights for you. You can book one-way or round-trip flight tickets.
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SFO 7:45 AM20h 15m1 stopsSCL 7:00 AMSan Francisco - Santiago | Mon, Aug 4 | Delta Air Lines
SCL 10:45 PM14h 15m1 stopsSFO 10:00 AMSantiago - San Francisco | Tue, Aug 12 | Delta Air Lines$671 $94528% OFF28% OFF$945 $671 -
SFO 1:37 AM14h 47m1 stopsSCL 7:24 PMSan Francisco - Santiago | Fri, Jul 18 | Copa Airlines
SCL 4:10 AM22h 30m1 stopsSFO 11:40 PMSantiago - San Francisco | Fri, Jul 25 | Copa Airlines$684 $94528% OFF28% OFF$945 $684 -
SFO 10:55 AM16h 5m1 stopsSCL 6:00 AMSan Francisco - Santiago | Mon, Aug 11 | Delta Air Lines
SCL 10:45 PM14h 15m1 stopsSFO 10:00 AMSantiago - San Francisco | Mon, Aug 18 | LATAM Airlines$687 $94527% OFF27% OFF$945 $687
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SFO 12:35 PM14h 25m1 stopsSCL 6:00 AMSan Francisco - Santiago | Thu, Jul 3 | Delta Air Lines
SCL 8:40 PM16h 32m1 stopsSFO 10:12 AMSantiago - San Francisco | Thu, Jul 10 | Delta Air Lines$69227% OFF$945 $692
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SFO 10:55 AM16h 5m1 stopsSCL 6:00 AMSan Francisco - Santiago | Thu, Aug 7 | Delta Air Lines
SCL 10:45 PM14h 15m1 stopsSFO 10:00 AMSantiago - San Francisco | Sun, Aug 10 | Delta Air Lines$69926% OFF$945 $699
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SFO 10:55 AM16h 5m1 stopsSCL 6:00 AMSan Francisco - Santiago | Mon, Aug 11 | LATAM Airlines
SCL 11:00 AM37h 49m1 stopsSFO 9:49 PMSantiago - San Francisco | Mon, Aug 18 | LATAM Airlines$71125% OFF$945 $711 -
SFO 12:35 PM14h 25m1 stopsSCL 6:00 AMSan Francisco - Santiago | Tue, Jul 1 | Delta Air Lines
SCL 10:45 PM14h 15m1 stopsSFO 10:00 AMSantiago - San Francisco | Mon, Jul 7 | Delta Air Lines$72124% OFF$945 $721
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SFO 6:50 PM32h 10m1 stopsSCL 6:00 AMSan Francisco - Santiago | Sun, Aug 10 | Delta Air Lines
SCL 8:40 PM20h 44m1 stopsSFO 2:24 PMSantiago - San Francisco | Sun, Aug 17 | LATAM Airlines$72623% OFF$945 $726
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SFO 3:45 PM35h 15m1 stopsSCL 6:00 AMSan Francisco - Santiago | Sun, Aug 10 | LATAM Airlines
SCL 10:45 PM27h 26m1 stopsSFO 11:11 PMSantiago - San Francisco | Sun, Aug 17 | LATAM Airlines$73223% OFF$945 $732
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SFO 11:17 PM28h 23m1 stopsSCL 6:40 AMSan Francisco - Santiago | Mon, Aug 11 | Aeromexico
SCL 10:45 PM15h 48m1 stopsSFO 11:33 AMSantiago - San Francisco | Mon, Aug 18 | LATAM Airlines$73722% OFF$945 $737 -
SFO 1:00 PM17h 25m1 stopsSCL Invalid DateSan Francisco - Santiago | Sun, Jun 15 | Normal Airline
SCL 3:00 PM6hNonstopSFO 4:00 PMSantiago - San Francisco | Tue, Jun 17 | Normal AirlineFind More FlightsFind More Flights
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SFO 1:28 AM14h 56m1 stopsSCL 7:24 PMSan Francisco - Santiago | Sun, Aug 10 | Copa Airlines$322 $71055% OFF55% OFF$710 $322
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SFO 1:37 AM18h 31m1 stopsSCL 11:08 PMSan Francisco - Santiago | Thu, Jul 31 | Copa Airlines$327 $71054% OFF54% OFF$710 $327
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SFO 11:19 AM15h 41m1 stopsSCL 6:00 AMSan Francisco - Santiago | Wed, Jun 18 | Frontier Airlines$341 $71052% OFF52% OFF$710 $341 -
SFO 1:37 AM24h 27m1 stopsSCL 5:04 AMSan Francisco - Santiago | Sun, Jun 22 | Copa Airlines$34152% OFF$710 $341
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SFO 1:37 AM18h 31m1 stopsSCL 11:08 PMSan Francisco - Santiago | Mon, Jul 14 | Copa Airlines$34152% OFF$710 $341
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SFO 1:37 AM18h 31m1 stopsSCL 11:08 PMSan Francisco - Santiago | Thu, Jul 24 | Copa Airlines$34152% OFF$710 $341
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SFO 1:28 AM18h 40m1 stopsSCL 11:08 PMSan Francisco - Santiago | Sat, Aug 9 | Copa Airlines$34551% OFF$710 $345
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SFO 9:18 PM29h 42m1 stopsSCL 6:00 AMSan Francisco - Santiago | Wed, Jun 18 | United Airlines$34751% OFF$710 $347 -
SFO 6:00 AM21h1 stopsSCL 6:00 AMSan Francisco - Santiago | Wed, Jun 18 | Delta Air Lines$35350% OFF$710 $353
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SFO 1:37 AM18h 31m1 stopsSCL 11:08 PMSan Francisco - Santiago | Wed, Jul 23 | Copa Airlines$55422% OFF$710 $554
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SFO 1:00 PM17h 25m1 stopsSCL Invalid DateSan Francisco - Santiago | Sun, Jun 15 | Normal AirlineFind More FlightsFind More Flights
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Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.
Flight Info | San Francisco to Santiago
| Cheapest one-way flight price | $318 |
|---|---|
| Off-season for travel | April |
| Peak season for travel | June |
| Flight distance | 9,530.72 km |
| Popular airline | avianca |
When is the cheapest time to fly from San Francisco to Santiago?
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Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.
Frequently Asked Questions
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When are flight tickets from San Francisco (SFO) to Santiago (SCL) the cheapest?
Airlines adjust prices for flights from San Francisco to Santiago based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays. -
How much do flights from San Francisco (SFO) to Santiago (SCL) cost?
According to Trip.com's data, the lowest price is around $828.
How to find a cheap flight from San Francisco to Santiago
Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from San Francisco to Santiago. Book your flights at the right time and save more.
Be flexible with your travel dates to get the cheapest San Francisco to Santiago ticket.
Tap "Date" in the flight search bar to browse the calendar and find airfare from San Francisco to Santiago for the next six months in 2025. If you're looking to fly within the next three months, the lowest fare is $322 for a one-way ticket on Sun, Aug 10.
Compare cheap San Francisco to Santiago flight deals from hundreds of airlines.
Our powerful search system compares prices from over 500 airlines. So you can find the cheapest flights from San Francisco to Santiago. The most affordable airline currently operating on this route is Copa Airlines.
Set up a Price Alert to track fare drops.
Set up a Price Alert for your San Francisco to Santiago route to track ticket prices effortlessly—no need to check manually every day.
Don't miss out on cheap San Francisco to Santiago flight deals and promo codes.
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Book early or wait unitl the last minute to fine the best fares.
It's always better to book early! Airlines typically release their lowest fares about a year before departure, so check as soon as flights become available. If you miss that window, you may still find great deals closer to your travel date.
Search for flights on the go.
For the best booking experience on the go, download Trip.com and search for cheap flights from San Francisco to Santiago to access exclusive deals just for you.
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