Cheap flight from San Francisco to St. Louis from $270

Frequently Asked Questions

• Which airlines offer direct flights from San Francisco to St. Louis?

  At the moment, you can catch a nonstop flight from San Francisco to St. Louis with the following airlines, including: United Airlines Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.

• How long does it take to fly from San Francisco (SFO) to St. Louis (STL) and what is the distance?

  It takes around 3 hours 54 minutes to fly from San Francisco (SFO) to St. Louis (STL).

• When is the best time to book flights from San Francisco to St. Louis?

  By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from San Francisco to St. Louis is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.

• How many flights are there per week from San Francisco to St. Louis?

  Based on Trip.com data in the past 4 weeks, there is 7 flight per week flying from San Francisco to St. Louis. You can check the weekly schedule for popular airlines on this route below: United Airlines: S/M/T/W/T/F/S -- UA336 (10:36)

• When are flight tickets from San Francisco (SFO) to St. Louis (STL) the cheapest?

  The cheapest months to fly from San Francisco to St. Louis is November, when demand for travel is lower.

• Which upcoming date is cheapest to fly from San Francisco to St. Louis on?

  After crunching the numbers on our November flight calendar, it's currently cheapest to fly from San Francisco to St. Louis on November 17, 2025 with Frontier Airlines, with prices starting at $138.

• Which airports can I fly to for St. Louis from San Francisco?

  You can land at any one of the following hubs in St. Louis, with San Francisco International Airport to St. Louis Lambert International Airport (SFO-STL) is by far the most common option on this route: St. Louis Lambert International Airport (STL) St. Louis Downtown Airport (CPS).

• Is there any time difference between San Francisco and St. Louis?

  The time difference between St. Louis and San Francisco is 2h.

• How do I change or cancel my ticket from San Francisco to St. Louis?

  Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.