Trip.com
>
Flights
>
Flights to United States
>
Flights to Illinois
>
Flights to Chicago
Hotels in Chicago
>
Flights from Santiago to Chicago

Find flight deals from Santiago to Chicago for the next 3 months. Book one way flights from $292 or round trip flights from $548.

      • SCL 3:20 PM
        31h
        1 stop
        ORD 9:20 PM
        Santiago - Chicago | Sun, Sep 6 | avianca
        ORD 11:20 PM
        23h
        1 stop
        SCL 12:20 AM
        Chicago - Santiago | Fri, Sep 11 | avianca
        $548 $902
        39% off
        39% off
        $902 $548
      • SCL 12:06 AM
        14h 53m
        1 stop
        ORD 1:59 PM
        Santiago - Chicago | Sun, Sep 6 | Copa Airlines
        ORD 3:20 PM
        12h 50m
        1 stop
        SCL 6:10 AM
        Chicago - Santiago | Fri, Sep 11 | Copa Airlines
        $555 $902
        38% off
        38% off
        $902 $555
      • SCL 10:55 PM
        19h 6m
        1 stop
        ORD 5:01 PM
        Santiago - Chicago | Sun, Sep 6 | Delta Air Lines
        ORD 6:48 PM
        32h 47m
        1 stop
        SCL 5:35 AM
        Chicago - Santiago | Fri, Sep 11 | Delta Air Lines
        $575 $902
        36% off
        36% off
        $902 $575
      • SCL 8:50 PM
        19h 15m
        1 stop
        ORD 3:05 PM
        Santiago - Chicago | Sun, Sep 6 | American Airlines
        ORD 2:30 PM
        15h 35m
        1 stop
        SCL 8:05 AM
        Chicago - Santiago | Fri, Sep 11 | American Airlines
        $720
        20% off
        $902 $720
      • SCL 8:40 PM
        14h 19m
        1 stop
        MDW 9:59 AM
        Santiago - Chicago | Sun, Sep 6 | LATAM Airlines
        ORD 6:00 AM
        23h 25m
        1 stop
        SCL 7:25 AM
        Chicago - Santiago | Fri, Sep 11 | Delta Air Lines
        $838
        7% off
        $902 $838
      • SCL 1:00 PM
        17h 25m
        1 stop
        CHI 2:00 PM
        Santiago - Chicago | Fri, Jul 24 | Normal Airline
        CHI 3:00 PM
        6h
        Nonstop
        SCL 4:00 PM
        Chicago - Santiago | Sun, Jul 26 | Normal Airline
        Find more flights
        Find more flights
      • SCL 12:30 AM
        21h 50m
        1 stop
        ORD 9:20 PM
        Santiago - Chicago | Thu, Aug 27 | avianca
        $292 $482
        39% off
        39% off
        $482 $292
      • SCL 12:30 AM
        21h 50m
        1 stop
        ORD 9:20 PM
        Santiago - Chicago | Fri, Sep 4 | avianca
        $304 $482
        37% off
        37% off
        $482 $304
      • SCL 7:40 AM
        15h 40m
        1 stop
        ORD 9:20 PM
        Santiago - Chicago | Wed, Sep 16 | avianca
        $305 $482
        37% off
        37% off
        $482 $305
      • SCL 6:40 AM
        15h 40m
        1 stop
        ORD 9:20 PM
        Santiago - Chicago | Thu, Aug 20 | avianca
        $305
        37% off
        $482 $305
      • SCL 2:14 AM
        23h 48m
        1 stop
        ORD 1:02 AM
        Santiago - Chicago | Fri, Sep 4 | Copa Airlines
        $309
        36% off
        $482 $309
      • SCL 12:06 AM
        25h 56m
        1 stop
        ORD 1:02 AM
        Santiago - Chicago | Sat, Aug 29 | Copa Airlines
        $311
        35% off
        $482 $311
      • SCL 4:14 AM
        21h 48m
        1 stop
        ORD 1:02 AM
        Santiago - Chicago | Sun, Aug 30 | Copa Airlines
        $313
        35% off
        $482 $313
      • SCL 2:56 AM
        36h 3m
        1 stop
        ORD 1:59 PM
        Santiago - Chicago | Tue, Sep 1 | Copa Airlines
        $313
        35% off
        $482 $313
      • SCL 3:20 PM
        31h
        1 stop
        ORD 9:20 PM
        Santiago - Chicago | Tue, Jul 28 | avianca
        $338
        30% off
        $482 $338
      • SCL 3:20 PM
        31h
        1 stop
        ORD 9:20 PM
        Santiago - Chicago | Tue, Aug 4 | avianca
        $448
        7% off
        $482 $448
      • SCL 1:00 PM
        17h 25m
        1 stop
        CHI 2:00 PM
        Santiago - Chicago | Fri, Jul 24 | Normal Airline
        Find more flights
        Find more flights

Find cheap airlines flights from Santiago to Chicago

You can choose from 1 airlines that fly from Santiago to Chicago, including avianca, avianca has lowest fares on this route.
avianca logo avianca
Airlines are determined based on actual purchased flight tickets from Santiago to Chicago according to previous 12 months data from Trip.com.

Flight Info | Santiago to Chicago

The distance between Santiago and Chicago is approximately 8,544.66 km. Based on Trip.com's data travel demand peaks in July. The off-season for travel is October.

Cheapest one-way flight price $292
Cheapest round-trip ticket price $548
Off-season for travel October
Peak season for travel July
Flight distance 8,544.66 km
Popular airline avianca
Flight statistics for the Santiago–Chicago route are based on aggregated booking data from Trip.com over the past 12 months.

Frequently Asked Questions

  • What are the cheapest flights from Santiago to Chicago (SCL-CHI)?

    Based on Trip.com data, avianca offers one-way fares as low as $292 on Cheapest nonstop routes (e.g. SCL to ORD on Thu, Aug 27), while avianca offers Cheapest nonstop round-trips from $548 departing on Sun, Sep 6 and returning on Fri, Sep 11.
  • At the moment, several airlines serve connecting flights from Santiago to Chicago, including: avianca Selected airlines are based on historical data collected from flight bookings made by users on Trip.com within the last 90 days.
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Santiago to Chicago is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • To find best deals on flights from Santiago to Chicago, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Thu, Aug 27, with one-way flights priced at just $292.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is avianca.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Chicago travel is around July.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Santiago to Chicago is October, when demand for travel is lower.
  • After crunching the numbers on our July flight calendar, it's currently cheapest to fly from Santiago to Chicago on July 28, 2026 with avianca, with prices starting at $303.
  • You can land at any one of the following hubs in Chicago, with Arturo Merino Benitez International Airport to O'Hare International Airport (SCL-ORD) is by far the most common option on this route: O'Hare International Airport (ORD) Chicago Midway International Airport (MDW) Chicago Rockford International Airport (RFD).
  • The time difference between Chicago and Santiago is 2h.
  • Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

Explore More Popular Flights

Note: Prices shown on this page are estimated lowest price and include all taxes and fees found in the last 24 hours.

Book with no extra fees

Prices displayed in this page are all-inclusive prices (incl. taxes, fuel surcharge, civil aviation development fund, etc) with all fees confirmed before payment. Fees for luggage, meals, WLAN, or other additional services are also included as shown in the flight cards.

Real-time pricing updates

Prices, availability, and travel information on this page were updated within last 24 hours—even in real-time. The more popular the route, the more precise the data.

Change & Cancellation Policy

Trip.com displays flight cancellation and change policies for each flight ticket during the booking process, including fees and applicable conditions. Please check the following scenarios:
Voluntary cancellation/change:
To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy.
Cancellation/change due to a flight schedule change:
If the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.