Flight Info | Santiago to Sao Paulo

The distance between Santiago and Sao Paulo is approximately 2,595.22 km. It takes around 4 hours 2 minutes on average to fly from Santiago to Sao Paulo. Based on Trip.com's data, travel demand peaks in January. The cheapest month to book is December.

Cheapest one-way
$99
Sky Airline Sky Airline SCL-SAO 3h 52m · Nonstop Wed, Oct 7
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Cheapest round-trip
$166
Sky Airline Sky Airline SCL-SAO 3h 55m · Nonstop Fri, Aug 28 - Sun, Aug 30
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When to travel
October
Cheapest
January
Peak season for travel
Route details
2,595.22 km
Flight distance
4h 2m
Average flight time

Book direct flights from Santiago to Sao Paulo: One way flights from $99, round trip flights from $166. Find flight deals for the next 3 months below.

Popular airlines from Santiago to Sao Paulo

You can choose from 2 airlines that fly from Santiago to Sao Paulo, including LATAM Airlines, JetSMART Airlines, Sky Airline has lowest fares on this route.
LATAM Airlines logo LATAM Airlines
JetSMART Airlines logo JetSMART Airlines
Airlines are determined based on actual purchased flight tickets from Santiago to Sao Paulo according to previous 12 months data from Trip.com.

Trip.com price insights on flights from Santiago to Sao Paulo

Which month has the cheapest one-way flights from Santiago to Sao Paulo?

The average price of one-way flights from Santiago to Sao Paulo purchased by Trip.com users by month over the past 12 months.

Based on Trip.com’s data, the cheapest month for flights from Santiago to Sao Paulo is October, with an average price of $155; while the month with the highest flight price is usually April, with an average price of up to $301.

$301
$228
$155
$82
    Cheapest
  • $189
    Aug
  • $195
    Sep
  • $155
    Oct
  • $175
    Nov
  • $177
    Dec
  • $287
    Jan
  • $242
    Feb
  • $215
    Mar
  • $301
    Apr
  • $261
    May
  • $195
    Jun
  • $192
    Jul

What is the cheapest month for round-trip flights from Santiago to Sao Paulo?

Average price of round-trip flights from Santiago to Sao Paulo purchased by Trip.com users by month over the past 12 months

According to historical data from Trip.com, the lowest prices for flights from Santiago to Sao Paulo are found during September, with an average price of $299. Conversely, the highest prices are found during January, with an average price of up to $549.

$549
$424
$299
$174
    Cheapest
  • $349
    Aug
  • $299
    Sep
  • $316
    Oct
  • $343
    Nov
  • $376
    Dec
  • $549
    Jan
  • $365
    Feb
  • $329
    Mar
  • $416
    Apr
  • $374
    May
  • $317
    Jun
  • $395
    Jul

When is the cheapest day to fly from Santiago to Sao Paulo during Labor Day?

Data is based on the lowest one-way price from Santiago to Sao Paulo during Labor Day on Trip.com in the past 3 days.

Labor Day is scheduled for Sep 7. The cheapest flights from Santiago to Sao Paulo are available on Sep 9, with fares starting at $155.

$211
$183
$155
$127
    Cheapest
  • $180
    3
    Sep
  • $182
    4
  • $167
    5
  • $211
    6
  • $175
    7
  • $199
    8
  • $155
    9

Frequently Asked Questions

  • What are the cheapest flights from Santiago to Sao Paulo (SCL-SAO)?

    Based on Trip.com data, Sky Airline offers one-way fares as low as $99 on Cheapest nonstop routes (e.g. SCL to GRU on Wed, Oct 7), while Sky Airline offers Cheapest nonstop round-trips from $166 departing on Fri, Aug 28 and returning on Sun, Aug 30.
  • At the moment, you can catch a nonstop flight from Santiago to Sao Paulo with the following airlines, including: LATAM Airlines JetSMART Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.
  • It takes around 4 hours 2 minutes to fly from Santiago (SCL) to Sao Paulo (SAO).
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Santiago to Sao Paulo is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • Based on Trip.com data in the past 4 weeks, there is 103 flight per week flying from Santiago to Sao Paulo. You can check the weekly schedule for popular airlines on this route below: LATAM Airlines: S/M/T/W/T/F/S -- LA754 (08:37) LATAM Airlines: S/M/T/W/T/F/S -- LA750 (12:12)
  • To find best deals on flights from Santiago to Sao Paulo, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Wed, Oct 7, with one-way flights priced at just $99.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is Sky Airline.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Sao Paulo travel is around January.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Santiago to Sao Paulo is December, when demand for travel is lower.
  • After crunching the numbers on our August flight calendar, it's currently cheapest to fly from Santiago to Sao Paulo on August 11, 2026 with Sky Airline, with prices starting at $103.
  • You can land at any one of the following hubs in Sao Paulo, with Arturo Merino Benitez International Airport to São Paulo/Guarulhos–Governor André Franco Montoro International Airport (SCL-GRU) is by far the most common option on this route: São Paulo/Guarulhos–Governor André Franco Montoro International Airport (GRU) São Paulo–Congonhas Airport (CGH) Viracopos International Airport (VCP).
  • The time difference between Sao Paulo and Santiago is 1h.
  • Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.
  • Based on Trip.com data for flights departing in the next 30 days, the average one-way fare from Santiago to Sao Paulo is $240. Fares vary by travel date, airline and availability.
  • Based on Trip.com data for travel in the next 30 days, the average round-trip fare from Santiago to Sao Paulo is $375. The final price depends on the outbound and return dates, airline and fare conditions.
  • Enter Santiago and Sao Paulo, choose your travel dates and passengers, then compare flights by price, duration and baggage. Select a fare, review the change and cancellation rules, enter traveler details and complete payment to receive your confirmation.
  • JetSMART and Sky Airlineare the most popular budget airlines flying from Santiago to Sao Paulo. Check baggage, seat and payment fees before comparing the final price.

Note: Prices shown on this page are estimated lowest price and include all taxes and fees found in the last 24 hours.

Book with no extra fees

Prices displayed in this page are all-inclusive prices (incl. taxes, fuel surcharge, civil aviation development fund, etc) with all fees confirmed before payment. Fees for luggage, meals, WLAN, or other additional services are also included as shown in the flight cards.

Real-time pricing updates

Prices, availability, and travel information on this page were updated within last 24 hours—even in real-time. The more popular the route, the more precise the data.

Change & Cancellation Policy

Trip.com displays flight cancellation and change policies for each flight ticket during the booking process, including fees and applicable conditions. Please check the following scenarios:
Voluntary cancellation/change:
To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy.
Cancellation/change due to a flight schedule change:
If the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.