Find cheap airlines flights from Santo Domingo to Madrid

Choose from 3 carriers that fly from Santo Domingo to Madrid, including Iberia, World2Fly Airlines, and Air Europa. Enjoy the cheapest tickets on this route with World2Fly Airlines.

Book direct flights from Santo Domingo to Madrid: One way flights from $242, round trip flights from $630. Find flight deals for the next 3 months below.

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Flight Info | Santo Domingo to Madrid

The distance between Santo Domingo and Madrid is about 6,706.66 km. It takes around 8 hours 21 minutes on average to fly from Santo Domingo to Madrid. The most popular month to Madrid is January. The off-season for travel is December.

Cheapest one-way flight price$242
Cheapest round-trip ticket price$630
Off-season for travelDecember
Peak season for travelJanuary
Flight distance6,706.66 km
Average flight time8 hours 21 minutes
Popular airlineIberia

When is the cheapest time to fly from Santo Domingo to Madrid?

The cheapest time for Santo Domingo to Madrid flights: Nov 16 to Nov 23 — one way flight prices from $242.

Cheapest flights
From price
Search
  • 29
  • 916
  • 1623
  • 2330
  • Dec

    307
  • 714
  • 1421
  • 2128
  • Jan

    284
  • 411
  • 1118
  • 1825
Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

  • Which airlines offer direct flights from Santo Domingo to Madrid?

    At the moment, you can catch a nonstop flight from Santo Domingo to Madrid with the following airlines, including: Iberia World2Fly Air Europa Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.
  • It takes around 8 hours 21 minutes to fly from Santo Domingo (SDQ) to Madrid (MAD).
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Santo Domingo to Madrid is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • Based on Trip.com data in the past 4 weeks, there is 15 flight per week flying from Santo Domingo to Madrid. You can check the weekly schedule for popular airlines on this route below: Air Europa: S/M/T/W/T/F/S -- UX088 (22:38)
  • The cheapest months to fly from Santo Domingo to Madrid is December, when demand for travel is lower.
  • After crunching the numbers on our November flight calendar, it's currently cheapest to fly from Santo Domingo to Madrid on November 16, 2025 with World2Fly, with prices starting at $284.
  • You can land at any one of the following hubs in Madrid, with Las Americas International Airport to Madrid Barajas Airport (SDQ-MAD) is by far the most common option on this route: Madrid Barajas Airport (MAD).
  • The time difference between Madrid and Santo Domingo is 5h.
  • Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.