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Flights from Syracuse to Santiago

Find flight deals from Syracuse to Santiago for the next 3 months. Book one way flights from $221 or round trip flights from $614.

      • SYR 5:15 AM
        7h 12m
        1 stop
        STI 12:27 PM
        Syracuse - Santiago | Mon, Jul 27 | Delta Air Lines
        STI 6:00 AM
        17h 12m
        1 stop
        SYR 11:12 PM
        Santiago - Syracuse | Mon, Aug 3 | Delta Air Lines
        $614 $1,286
        52% off
        52% off
        $1,286 $614
      • SYR 4:55 PM
        9h
        1 stop
        STI 1:55 AM
        Syracuse - Santiago | Wed, Jul 29 | Delta Air Lines
        STI 6:00 AM
        17h 12m
        1 stop
        SYR 11:12 PM
        Santiago - Syracuse | Thu, Aug 6 | Delta Air Lines
        $668 $1,286
        48% off
        48% off
        $1,286 $668
      • SYR 6:10 AM
        13h 24m
        1 stop
        STI 7:34 PM
        Syracuse - Santiago | Fri, Jul 17 | Delta Air Lines
        STI 8:59 PM
        13h 40m
        1 stop
        SYR 10:39 AM
        Santiago - Syracuse | Thu, Jul 23 | Delta Air Lines
        $685 $1,286
        47% off
        47% off
        $1,286 $685
      • SYR 8:35 PM
        27h 16m
        1 stop
        STI 11:51 PM
        Syracuse - Santiago | Sun, Jul 19 | Jetblue Airways
        STI 6:48 AM
        17h 15m
        1 stop
        SYR 12:03 AM
        Santiago - Syracuse | Sat, Jul 25 | Jetblue Airways
        $913
        28% off
        $1,286 $913
      • SYR 1:00 PM
        17h 25m
        1 stop
        STI 2:00 PM
        Syracuse - Santiago | Tue, Jul 14 | Normal Airline
        STI 3:00 PM
        6h
        Nonstop
        SYR 4:00 PM
        Santiago - Syracuse | Thu, Jul 16 | Normal Airline
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      • SYR 7:21 PM
        17h 1m
        1 stop
        STI 12:22 PM
        Syracuse - Santiago | Sat, Aug 15 | American Airlines
        $221 $630
        65% off
        65% off
        $630 $221
      • SYR 7:21 PM
        17h 1m
        1 stop
        STI 12:22 PM
        Syracuse - Santiago | Wed, Aug 26 | American Airlines
        $373 $630
        41% off
        41% off
        $630 $373
      • SYR 7:00 AM
        18h 48m
        1 stop
        STI 1:48 AM
        Syracuse - Santiago | Wed, Jul 15 | Jetblue Airways
        $447 $630
        28% off
        28% off
        $630 $447
      • SYR 1:00 PM
        17h 25m
        1 stop
        STI 2:00 PM
        Syracuse - Santiago | Tue, Jul 14 | Normal Airline
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Displayed flight fares from Syracuse to Santiago are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

Flight Info | Syracuse to Santiago

The distance between Syracuse and Santiago is approximately 2,685.7 km. Based on Trip.com's data travel demand peaks in December. The off-season for travel is October.

Cheapest one-way flight price$221
Cheapest round-trip ticket price$614
Off-season for travelOctober
Peak season for travelDecember
Flight distance2,685.7 km
Flight statistics for the Syracuse–Santiago route are based on aggregated booking data from Trip.com over the past 12 months.

Frequently Asked Questions

  • What are the cheapest flights from Syracuse to Santiago (SYR-STI)?

    Based on Trip.com data, American Airlines offers one-way fares as low as $221 on Cheapest nonstop routes (e.g. SYR to STI on Sat, Aug 15), while Delta Air Lines offers Cheapest nonstop round-trips from $614 departing on Mon, Jul 27 and returning on Mon, Aug 3.
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Syracuse to Santiago is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • To find best deals on flights from Syracuse to Santiago, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Sat, Aug 15, with one-way flights priced at just $221.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is American Airlines.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Santiago travel is around December.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Syracuse to Santiago is October, when demand for travel is lower.
  • After crunching the numbers on our July flight calendar, it's currently cheapest to fly from Syracuse to Santiago on July 21, 2026 with Delta Air Lines, with prices starting at $614.
  • The time difference between Santiago and Syracuse is 1h.
  • Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

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Note: Prices shown on this page are estimated lowest price and include all taxes and fees found in the last 24 hours.

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Prices displayed in this page are all-inclusive prices (incl. taxes, fuel surcharge, civil aviation development fund, etc) with all fees confirmed before payment. Fees for luggage, meals, WLAN, or other additional services are also included as shown in the flight cards.

Real-time pricing updates

Prices, availability, and travel information on this page were updated within last 24 hours—even in real-time. The more popular the route, the more precise the data.

Change & Cancellation Policy

Trip.com displays flight cancellation and change policies for each flight ticket during the booking process, including fees and applicable conditions. Please check the following scenarios:
Voluntary cancellation/change:
To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy.
Cancellation/change due to a flight schedule change:
If the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.