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Hotels in Santa Cruz
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Best hotels in Santa Cruz

Explore Santa Cruz with 66 stays near iconic landmarks, luxury hotels, and top boutiques for the best shopping and dining

Marriott Santa Cruz de la Sierra Hotel
8.8 (102 reviews)

Marriott Santa Cruz de la Sierra Hotel ★★★★★

📍 4to Anillo Entre Radial 23 Y, Av. Las Ramblas S/N, Santa Cruz

"Hotel room hot water is not hot enough"

1 night $159
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Lido Hotel
8.9 (42 reviews)

Lido Hotel ★★★

📍 Calle 21 de Mayo 527, Santa Cruz

"My friend and I split the bill for one night, about 2,500 yen per person, including breakfast, which I thought was a bargain. It was clean. The receptionist was very kind, carrying our suitcases to our room. The square is about a 10-minute walk away. The shower has a quick release, similar to a waterfall bath. Soap, shampoo, and conditioner were provided, and the amenities were plentiful."

1 night $21
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Ibis Santa Cruz de la Sierra
8.9 (48 reviews)

Ibis Santa Cruz de la Sierra ★★★

📍 Av. Cristobal De Mendoza, Santa Cruz

"This hotel is suitable for both leisure and business trips. The breakfast is plentiful, the hotel restaurant has excellent drinks and delicious, unique dishes, and it's convenient to hail a taxi right outside. Highly recommended."

1 night $39
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Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
9.0 (101 reviews)

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel ★★★★★

📍 Los Tajibos, a Tribute Portfolio Hotel, Av. San Martín 455, Santa Cruz

"One of the best hotel at Santa Cruz and the swimming pool is great!"

1 night $112
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Tryp by Wyndham Santa Cruz
8.8 (75 reviews)

Tryp by Wyndham Santa Cruz ★★★★

📍 9 Este 4, Santa Cruz

"The breakfast type is single and the amount is not much. It is often a little later and there is nothing. The window of the room is open in a patio. The staff is friendly."

1 night $100
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Hotel Osho
8.2 (24 reviews)

Hotel Osho ★★★

📍 Ave Suarez Arana 751, Santa Cruz

"Excellent hôtel, Nice staff, spacious room!!"

1 night $41
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Gran Hotel Santa Cruz
7.2 (2 reviews)

Gran Hotel Santa Cruz ★★★

📍 Rene Moreno, Santa Cruz

"I stayed at this hotel for 2 nights as part of a group tour. I arrived quite early and I was able to get into my room straight away which was nice. The hotel is conveniently located a couple of streets from the central square. My room was a very good size and clean. The bed was large and comfortable enough. The plug sockets weren't in the most convenient locations. The bathroom was decent, there was a sign saying that the hot water pressure could be dodgy so they advise you to turn it on 5 minutes before getting into the shower. It did make some gurgling noises and the pressure was inconsistent at first. The air conditioning and wifi worked good enough. I didn't have much time to try their breakfast, but it looked very good with a lot of choice, and they brought you either scrambled eggs or an omelette. Overall a good stay, if you want somewhere close to the centre of Santa Cruz this is a solid choice. It gets 3 rather than 4 stars from me given that's what I would rate it by international standards."

1 night $59
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Hotel Cortez
9.2 (55 reviews)

Hotel Cortez ★★★★★

📍 Av. Cristóbal De Mendoza 280, Santa Cruz

"This is a very old hotel, located on the Second Ring Road. You must stay in a room near the front desk facing away from the road. Otherwise, if you stay in the main building, it will be very noisy. There is a lot of traffic on the Second Ring Road, and a lot of old Japanese cars make a lot of noise. The soundproofing in the room is not very good, so it will be very noisy. The hotel breakfast is good, which is considered a good breakfast in the local area. The waiter's attitude is very good and he is very willing to help."

1 night $119
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Hotel LP Santa Cruz Centro
8.0 (22 reviews)

Hotel LP Santa Cruz Centro ★★★

📍 Av. Ejercito Nacional 290, Santa Cruz

"$300 and a pair of earrings was stolen from my Fanny pack. I told the front staff who told me management would call me and they never did. I also asked to speak with the owner and never heard back. It’s been 3 weeks and no response. They never gave me the number to the manager. If going to this hotel, put EVERYTHING in the safe and lock your luggage. My mom’s carry on was opened and shuffled through as well."

1 night $44
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Find the perfect stay for your travel style in Santa Cruz

Apart Hotel Toborochi Hotels in Santa Cruz

Apart Hotel Toborochi

"The hotel is in a very good location"

Details ➡
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Hotel Maywa Hotels in Santa Cruz

Hotel Maywa

"I loved the hotel. I was very comfortable during my stay. The bed was super comfortable and the shower was relaxing, as was the staff's attention. I felt right at home. Thank you so much, Hotel Maywa."

$33 Details ➡
Chairu Eco Hotel Hotels in Santa Cruz

Chairu Eco Hotel

"The room was nice."

$50 Details ➡
Hotel G Hotels in Santa Cruz

Hotel G

"I will consider it next time"

$30 Details ➡
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Real traveler reviews of Santa Cruz hotels

9.0
Excellent community rating
Real & verified guest reviews from all over the world
W

CL Wilson du

Solo traveler
Marriott Santa Cruz de la Sierra Hotel ★★★★★
"The gaps in the curtains are too big, the air conditioner is mobile, it keeps turning on and off automatically all night, and the noise is super loud!"
★★★★★
2024-09-22
X

Xiangzhouguyewang

Business traveler
Lido Hotel ★★★
"Very good, everything is satisfactory."
★★★★★
2025-11-03
G

ES Guest User

Couple
Ibis Santa Cruz de la Sierra ★★★
"We spent three days in Santa Cruz. The hotel was fantastic, one of the best we stayed in on our trip through Bolivia. The bed was very comfortable, the cleanliness was impeccable, and the breakfast was excellent. It's located in the upscale Equipetrol area. There are many good and affordable restaurants nearby, as well as some rather expensive clothing stores."
★★★★★
2026-02-21
S

CN Suobotekaqiurui

Business traveler
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel ★★★★★
"It is one of the best hotels in Bolivia, very distinctive and clean"
★★★★★
2024-09-09
G

Guest User

Family
Tryp by Wyndham Santa Cruz ★★★★
"Great experience at this hotel, would stay here again!"
★★★★★
2026-03-13
G

Guest User

Solo traveler
Hotel Osho ★★★
"Nice Hotel. The Roms are big and clean, bedding is fine, and a/c works well. I enjoyed the rich coffee at breakfast with tasty papaya, corncakes, and eggs made to order. Two improvements would be to install dark curtains, and to have a better shower head/shower fixture is too high and cannot be hand held. Good value!"
★★★★★
2024-10-26
G

Guest User

Other
Gran Hotel Santa Cruz ★★★
"I stayed at this hotel for 2 nights as part of a group tour. I arrived quite early and I was able to get into my room straight away which was nice. The hotel is conveniently located a couple of streets from the central square. My room was a very good size and clean. The bed was large and comfortable enough. The plug sockets weren't in the most convenient locations. The bathroom was decent, there was a sign saying that the hot water pressure could be dodgy so they advise you to turn it on 5 minutes before getting into the shower. It did make some gurgling noises and the pressure was inconsistent at first. The air conditioning and wifi worked good enough. I didn't have much time to try their breakfast, but it looked very good with a lot of choice, and they brought you either scrambled eggs or an omelette. Overall a good stay, if you want somewhere close to the centre of Santa Cruz this is a solid choice. It gets 3 rather than 4 stars from me given that's what I would rate it by international standards."
★★★★★
2026-08-29
F

HK Ferdosh

Business traveler
Hotel Cortez ★★★★★
"Perhaps the best hotel to stay in town for business travel. Comfortable, convenient, amazing wet area facilities, wonderful breakfast, staff that goes above and beyond."
★★★★★
2025-11-21
i

ES ivan Quintero Calderón

Couple
Hotel LP Santa Cruz Centro ★★★
"The truth is that I have already repeated because of the tranquility of the place and the hotel The breakfasts are very rich, very tidy and everything is nice!! And above all their coffee... juice... everything That's really cold!!!! The blanket didn't taste like much to me, but the jacuzzi was spectacular, the service, the attention and the taxis to the airport were viru viru, about Hugo and José 5 stars to them too. Thank you!!! We will return!! Long live Spain!! And MY ANDALUSIA 💚 AN ANDALUSIAN WAS HERE"
★★★★★
2024-05-31

Santa Cruz travel info

⚡

Power Plug & Voltage

115V/230V/Type A/C

💵

Exchange Rate

1 USD ≈ 11.90 BOB

💳

Local Payment

Cash/Cards/QR

📱

Connectivity

Entel/Tigo/Viva

🌡️

Current Weather

Mostly clear

More Santa Cruz hotel info

Data type

Details

Number of reviews

1,119

Total properties

66

Weekday Avg. Price

$65

Weekend Avg. Price

$66

Trending hotel

Lido Hotel

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