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Tocumen International Airport to Brussels flight
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Cheap Flights from Tocumen International Airport to Brussels

Search for flights from Tocumen International Airport to Brussels and check out affordable one-way and round-trip options.

  • One way
  • Round-trip
sortSort by: Lowest Price
  • Sort by: Lowest Price
  • Sort by: Earliest Flight
      • PTY20:25
        14h 15m
        1 stop
        BRU17:40
        Panama City - Brussels|Tue, May 21|Air Europa
        $438$614
        28% OFF
        28% OFF
        $614$438
      • PTY20:25
        29h 40m
        2 stops
        BRU09:05
        Panama City - Brussels|Sun, May 26|Air Europa
        $452$614
        26% OFF
        26% OFF
        $614$452
      • PTY20:25
        14h 15m
        1 stop
        BRU17:40
        Panama City - Brussels|Mon, Jun 10|Air Europa
        $471$614
        23% OFF
        23% OFF
        $614$471
      • PTY17:20
        22h 10m
        1 stop
        BRU22:30
        Panama City - Brussels|Mon, May 27|Iberia
        $476
        $476
      • PTY17:20
        18h 40m
        1 stop
        BRU19:00
        Panama City - Brussels|Sun, May 26|Iberia
        $478
        $478
      • PTY17:10
        38h 5m
        2 stops
        BRU14:15
        Panama City - Brussels|Mon, Jun 17|Iberia
        $482
        $482
      • PTY17:10
        32h 55m
        2 stops
        BRU09:05
        Panama City - Brussels|Mon, Jul 1|Iberia
        $484
        $484
      • PTY17:20
        14h 25m
        1 stop
        BRU14:45
        Panama City - Brussels|Sat, May 18|Iberia
        $492
        $492
      • PTY20:25
        14h 15m
        1 stop
        BRU17:40
        Panama City - Brussels|Wed, May 22|Air Europa
        $498
        $498
      • PTY20:25
        14h 15m
        1 stop
        BRU17:40
        Panama City - Brussels|Thu, May 23|Air Europa
        $498
        $498
      • PTY13:00
        3h 5m
        Direct
        BRU14:00
        Panama City - Brussels|Wed, May 8|Air Europa
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Selected Airlines from Tocumen International Airport to Brussels

See which airlines fly from Tocumen International Airport to Brussels. Find the airline that best meets your travel needs by comparing prices and treat yourself to an enjoyable journey.

Air Europa
From $438
Iberia
From $476
Turkish Airlines
From $522
Avianca
From $596
United Airlines
From $602
Copa Airlines
From $659
Air France
From $780
KLM
From $783
American Airlines
From $792
Delta Air Lines
From $822
ANA airlines
Find more flights and airlines

There are 2 airport(s) in Brussels. Discover the top routes now!

Learn about different airports in Brussels, find the best flight and transfer options, and plan your journey.

  • 0.62 km from downtown BrusselsCheapestClosest
    Brussels National Airport
    Tickets From
    $438
  • 49.65 km from downtown Brussels
    Brussels South Charleroi Airport
    Tickets From
    $678
Flight Schedule from Tocumen International Airport to Brussels

Check the schedule for flights from Tocumen International Airport to Brussels and find the flight that best matches your travel plans.

Flight info.
Departure
Arrival
Weekly Schedule

  1. CM228

    Copa Airlines

    07:39

    PTY

    5.7h

    13:18

    ORD

    --T-T-S
    Search

  2. SN9090

    Brussels Airlines

    15:45

    ORD

    8.2h

    05:55

    LHR

    SMTWTFS

  3. BA392

    British Airways

    07:55

    LHR

    1.2h

    10:05

    BRU

    SMTWTFS

  4. UA727

    United Airlines

    09:45

    PTY

    5.3h

    16:05

    EWR

    SMTWTFS
    Search

  5. UA110

    United Airlines

    18:00

    EWR

    7.3h

    06:20

    LHR

    SMTWTFS

  6. SN2106

    Brussels Airlines

    07:45

    LHR

    1.0h

    09:45

    BRU

    SMTWTFS

  7. UA1031

    United Airlines

    10:00

    PTY

    4.3h

    14:17

    IAH

    SMTWTFS
    Search

  8. UA880

    United Airlines

    16:20

    IAH

    9.3h

    07:40

    LHR

    SMTWTFS

  9. SN2094

    Brussels Airlines

    11:05

    LHR

    1.1h

    13:10

    BRU

    SMTWTFS

  10. IB6346

    Iberia

    17:10

    PTY

    10.2h

    10:20

    MAD

    S-T--FS
    Search

  11. IB3214

    Iberia

    16:40

    MAD

    2.3h

    19:00

    BRU

    SMTWT-S

  12. IB6346

    Iberia

    17:10

    PTY

    10.2h

    10:20

    MAD

    S-T--FS
    Search

  13. IB3012

    Iberia

    11:30

    MAD

    1.3h

    12:45

    BCN

    SMTWTFS

  14. VY8982

    Vueling Airlines

    15:15

    BCN

    2.3h

    17:30

    BRU

    SMTWT-S

  15. IB6346

    Iberia

    17:10

    PTY

    10.2h

    10:20

    MAD

    S-T--FS
    Search

  16. IB8954

    Iberia

    12:25

    MAD

    2.3h

    14:45

    BRU

    ---W---

  17. IB6346

    Iberia

    17:10

    PTY

    10.2h

    10:20

    MAD

    S-T--FS
    Search

  18. IB3210

    Iberia

    12:25

    MAD

    2.3h

    14:45

    BRU

    ------S

  19. TK800

    Turkish Airlines

    19:50

    PTY

    12.8h

    16:40

    IST

    --T-T-S
    Search

  20. TK1941

    Turkish Airlines

    18:50

    IST

    3.5h

    21:20

    BRU

    SMTWTFS

  21. TK801

    Turkish Airlines

    19:50

    PTY

    12.8h

    16:40

    IST

    S--W-F-
    Search

  22. TK1941

    Turkish Airlines

    18:50

    IST

    3.5h

    21:20

    BRU

    SMTWTFS

  23. UX056

    Air Europa

    20:25

    PTY

    9.8h

    13:15

    MAD

    SMTWT-S
    Search

  24. UX1173

    Air Europa

    15:15

    MAD

    2.4h

    17:40

    BRU

    SMTWTFS
Find more flights and airlines

Flight Info of Flights from Tocumen International Airport to Brussels

Cheapest nonstop flight price

$437

Off-season for travel

January

Peak season for travel

July

FAQs for Tocumen International Airport to Brussels Flights

  • What is the transportation method from the main airport to downtown in Brussels?

    • The distance from Brussels National Airport to downtown is about 10km. It takes about 30 minutes by taxi.
    • The distance from Brussels South Charleroi Airport to downtown is about 43km. It takes about 1 hour by taxi.

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