Trip.com
>
Flights
>
Flights to Dominican Republic
>
Flights to Santiago
Hotels in Santiago
>
Flights from Boston to Santiago

Book direct flights from Boston to Santiago: One way flights from $219, round trip flights from $516. Find flight deals for the next 3 months below.

      • Cheapest nonstop
        BOS 9:48 PM
        4h
        Nonstop
        STI 1:48 AM
        Boston - Santiago | Thu, Jul 16 | Jetblue Airways
        STI 5:30 AM
        3h 56m
        Nonstop
        BOS 9:26 AM
        Santiago - Boston | Thu, Jul 23 | Jetblue Airways
        $516 $673
        23% off
        23% off
        $673 $516
      • BOS 9:48 PM
        4h
        Nonstop
        STI 1:48 AM
        Boston - Santiago | Wed, Jul 22 | Jetblue Airways
        STI 5:30 AM
        3h 56m
        Nonstop
        BOS 9:26 AM
        Santiago - Boston | Sun, Jul 26 | Jetblue Airways
        $612 $673
        9% off
        9% off
        $673 $612
      • BOS 1:00 PM
        12h 55m
        1 stop
        STI 1:55 AM
        Boston - Santiago | Mon, Jul 20 | Delta Air Lines
        STI 8:59 PM
        10h 27m
        1 stop
        BOS 7:26 AM
        Santiago - Boston | Sun, Jul 26 | Delta Air Lines
        $476 $673
        28% off
        28% off
        $673 $476
      • BOS 11:09 AM
        8h 54m
        1 stop
        STI 8:03 PM
        Boston - Santiago | Tue, Sep 1 | American Airlines
        STI 1:32 PM
        22h 48m
        1 stop
        BOS 12:20 PM
        Santiago - Boston | Tue, Sep 8 | American Airlines
        $480
        28% off
        $673 $480
      • BOS 2:00 PM
        11h 55m
        1 stop
        STI 1:55 AM
        Boston - Santiago | Thu, Jul 23 | Delta Air Lines
        STI 1:52 PM
        9h 39m
        1 stop
        BOS 11:31 PM
        Santiago - Boston | Mon, Jul 27 | Delta Air Lines
        $492
        27% off
        $673 $492
      • BOS 9:48 PM
        4h
        Nonstop
        STI 1:48 AM
        Boston - Santiago | Thu, Jul 16 | Jetblue Airways
        STI 8:59 PM
        10h 16m
        1 stop
        BOS 7:15 AM
        Santiago - Boston | Thu, Jul 23 | Delta Air Lines
        $494
        27% off
        $673 $494
      • BOS 9:48 PM
        4h
        Nonstop
        STI 1:48 AM
        Boston - Santiago | Sun, Jul 19 | Jetblue Airways
        STI 6:00 AM
        15h 39m
        1 stop
        BOS 9:39 PM
        Santiago - Boston | Fri, Jul 24 | Delta Air Lines
        $524
        22% off
        $673 $524
      • BOS 12:41 PM
        10h 11m
        1 stop
        STI 10:52 PM
        Boston - Santiago | Tue, Sep 1 | United Airlines
        STI 6:00 AM
        8h 22m
        1 stop
        BOS 2:22 PM
        Santiago - Boston | Tue, Sep 8 | United Airlines
        $550
        18% off
        $673 $550
      • BOS 9:05 AM
        10h 29m
        1 stop
        STI 7:34 PM
        Boston - Santiago | Tue, Sep 1 | Delta Air Lines
        STI 1:32 PM
        6h 41m
        1 stop
        BOS 8:13 PM
        Santiago - Boston | Tue, Sep 8 | American Airlines
        $555
        18% off
        $673 $555
      • BOS 4:00 PM
        9h 55m
        1 stop
        STI 1:55 AM
        Boston - Santiago | Wed, Aug 19 | Delta Air Lines
        STI 8:59 PM
        16h 22m
        1 stop
        BOS 1:21 PM
        Santiago - Boston | Sun, Aug 23 | Delta Air Lines
        $559
        17% off
        $673 $559
      • BOS 6:05 AM
        6h 22m
        1 stop
        STI 12:27 PM
        Boston - Santiago | Tue, Jul 21 | Delta Air Lines
        STI 8:59 PM
        10h 27m
        1 stop
        BOS 7:26 AM
        Santiago - Boston | Mon, Jul 27 | Delta Air Lines
        $588
        13% off
        $673 $588
      • BOS 7:00 AM
        12h 34m
        1 stop
        STI 7:34 PM
        Boston - Santiago | Fri, Jul 24 | Delta Air Lines
        STI 6:00 AM
        10h 8m
        1 stop
        BOS 4:08 PM
        Santiago - Boston | Mon, Jul 27 | Delta Air Lines
        $588
        13% off
        $673 $588
      • BOS 1:00 PM
        17h 25m
        1 stop
        STI 2:00 PM
        Boston - Santiago | Fri, Jul 17 | Normal Airline
        STI 3:00 PM
        6h
        Nonstop
        BOS 4:00 PM
        Santiago - Boston | Sun, Jul 19 | Normal Airline
        Find more flights
        Find more flights
      • Cheapest nonstop
        BOS 9:45 PM
        4h
        Nonstop
        STI 1:45 AM
        Boston - Santiago | Wed, Aug 5 | Jetblue Airways
        $219 $305
        28% off
        28% off
        $305 $219
      • BOS 9:44 PM
        4h 1m
        Nonstop
        STI 1:45 AM
        Boston - Santiago | Thu, Aug 6 | Jetblue Airways
        $223 $305
        27% off
        27% off
        $305 $223
      • BOS 1:34 PM
        12h 21m
        1 stop
        STI 1:55 AM
        Boston - Santiago | Sat, Aug 22 | Delta Air Lines
        $170 $305
        44% off
        44% off
        $305 $170
      • BOS 6:05 AM
        13h 29m
        1 stop
        STI 7:34 PM
        Boston - Santiago | Tue, Aug 25 | Delta Air Lines
        $172
        44% off
        $305 $172
      • BOS 6:05 AM
        6h 25m
        1 stop
        STI 12:30 PM
        Boston - Santiago | Tue, Sep 1 | Delta Air Lines
        $175
        43% off
        $305 $175
      • BOS 6:05 AM
        6h 25m
        1 stop
        STI 12:30 PM
        Boston - Santiago | Sun, Sep 6 | Delta Air Lines
        $175
        43% off
        $305 $175
      • BOS 6:05 AM
        6h 25m
        1 stop
        STI 12:30 PM
        Boston - Santiago | Wed, Sep 9 | Delta Air Lines
        $175
        43% off
        $305 $175
      • BOS 6:05 AM
        6h 21m
        1 stop
        STI 12:26 PM
        Boston - Santiago | Fri, Sep 11 | Delta Air Lines
        $175
        43% off
        $305 $175
      • BOS 9:05 AM
        16h 50m
        1 stop
        STI 1:55 AM
        Boston - Santiago | Thu, Aug 20 | Delta Air Lines
        $176
        42% off
        $305 $176
      • BOS 6:05 AM
        13h 29m
        1 stop
        STI 7:34 PM
        Boston - Santiago | Sun, Aug 2 | Delta Air Lines
        $178
        42% off
        $305 $178
      • BOS 9:05 AM
        16h 50m
        1 stop
        STI 1:55 AM
        Boston - Santiago | Sat, Aug 15 | Delta Air Lines
        $207
        32% off
        $305 $207
      • BOS 1:34 PM
        12h 21m
        1 stop
        STI 1:55 AM
        Boston - Santiago | Fri, Aug 14 | Delta Air Lines
        $277
        9% off
        $305 $277
      • BOS 1:00 PM
        17h 25m
        1 stop
        STI 2:00 PM
        Boston - Santiago | Fri, Jul 17 | Normal Airline
        Find more flights
        Find more flights

Find cheap airlines flights from Boston to Santiago

You can choose from 2 airlines that fly from Boston to Santiago, including Jetblue Airways, Delta Air Lines, Jetblue Airways has lowest fares on this route.
Jetblue Airways logo Jetblue Airways
Delta Air Lines logo Delta Air Lines
Airlines are determined based on actual purchased flight tickets from Boston to Santiago according to previous 12 months data from Trip.com.

Flight Info | Boston to Santiago

The distance between Boston and Santiago is approximately 2,553.37 km. It takes around 3 hours 54 minutes on average to fly from Boston to Santiago. Based on Trip.com's data travel demand peaks in July. The off-season for travel is September.

Cheapest one-way flight price$170
Cheapest round-trip ticket price$476
Off-season for travelSeptember
Peak season for travelJuly
Flight distance2,553.37 km
Average flight time3 hours 54 minutes
Popular airlineJetblue Airways
Flight statistics for the Boston–Santiago route are based on aggregated booking data from Trip.com over the past 12 months.

Frequently Asked Questions

  • What are the cheapest flights from Boston to Santiago (BOS-STI)?

    Based on Trip.com data, Delta Air Lines offers one-way fares as low as $170 on Cheapest nonstop routes (e.g. BOS to STI on Sat, Aug 22), while Delta Air Lines offers Cheapest nonstop round-trips from $476 departing on Mon, Jul 20 and returning on Sun, Jul 26.
  • At the moment, you can catch a nonstop flight from Boston to Santiago with the following airlines, including: Jetblue Airways Delta Air Lines Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.
  • It takes around 3 hours 54 minutes to fly from Boston (BOS) to Santiago (STI).
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Boston to Santiago is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • Based on Trip.com data in the past 4 weeks, there is 13 flight per week flying from Boston to Santiago. You can check the weekly schedule for popular airlines on this route below: Jetblue Airways: S/M/T/W/T/F/S -- B62023 (14:08) Jetblue Airways: S/M/T/W/T/F/S -- B61323 (22:24)
  • To find best deals on flights from Boston to Santiago, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Sat, Aug 22, with one-way flights priced at just $170.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is Jetblue Airways.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Santiago travel is around July.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Boston to Santiago is September, when demand for travel is lower.
  • After crunching the numbers on our July flight calendar, it's currently cheapest to fly from Boston to Santiago on July 21, 2026 with Delta Air Lines, with prices starting at $497.
  • You can land at any one of the following hubs in Santiago, with Boston Logan International Airport to Cibao International Airport (BOS-STI) is by far the most common option on this route: Cibao International Airport (STI).
  • The time difference between Santiago and Boston is 1h.
  • Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

Explore More Popular Flights

Note: Prices shown on this page are estimated lowest price and include all taxes and fees found in the last 24 hours.

Book with no extra fees

Prices displayed in this page are all-inclusive prices (incl. taxes, fuel surcharge, civil aviation development fund, etc) with all fees confirmed before payment. Fees for luggage, meals, WLAN, or other additional services are also included as shown in the flight cards.

Real-time pricing updates

Prices, availability, and travel information on this page were updated within last 24 hours—even in real-time. The more popular the route, the more precise the data.

Change & Cancellation Policy

Trip.com displays flight cancellation and change policies for each flight ticket during the booking process, including fees and applicable conditions. Please check the following scenarios:
Voluntary cancellation/change:
To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy.
Cancellation/change due to a flight schedule change:
If the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.