Find cheap flights from Des Moines to St. Louis starting at $121.
Book one-way or return flights from Des Moines to St. Louis from as little as $121. Choose from the popular airlines below and book your flight today!
- One way
- Round-trip
- DSM11:374h 9m1 stopSTL15:46Tue, May 21|Des Moines - St. Louis|United Airlines$121$20340% OFF40% OFF$203$121
- DSM13:255h 6m1 stopSTL18:31Thu, Jul 4|Des Moines - St. Louis|American Airlines$122$20340% OFF40% OFF$203$122
- DSM11:374h 9m1 stopSTL15:46Tue, May 7|Des Moines - St. Louis|United Airlines$130$20336% OFF36% OFF$203$130
- DSM11:374h 9m1 stopSTL15:46Wed, May 22|Des Moines - St. Louis|United Airlines$140$140
- DSM11:324h 14m1 stopSTL15:46Sat, May 11|Des Moines - St. Louis|United Airlines$140$140
- DSM11:374h 9m1 stopSTL15:46Thu, May 9|Des Moines - St. Louis|United Airlines$141$141
- DSM11:304h 11m1 stopSTL15:41Wed, May 29|Des Moines - St. Louis|United Airlines$143$143
- DSM11:214h 19m1 stopSTL15:40Thu, Jul 4|Des Moines - St. Louis|United Airlines$144$144
- DSM08:006h 16m1 stopSTL14:16Sun, May 26|Des Moines - St. Louis|United Airlines$154$154
- DSM08:006h 23m1 stopSTL14:23Sun, May 12|Des Moines - St. Louis|United Airlines$156$156
- DSM13:003h 5mDirectSTL14:00Sat, May 4|Des Moines - St. Louis|United AirlinesFind More FlightsFind More Flights
Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.
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Find more flights and airlines
Discover different routes, airlines, and transfers and find the best alternative flights for your journey from Des Moines to St. Louis.
- CheapestDSM11:374h 9m1 transferSTL15:46Des Moines International Airport - St. Louis Lambert International AirportTue, May 21United Airlines$121
- DSM11:374h 9m1 transferSTL15:46Des Moines International Airport - St. Louis Lambert International AirportTue, May 21United Airlines$121Find More Flights
Frequently Asked Questions
How to find a cheap flight from Des Moines to St. Louis
Cheapest nonstop flight price | $120 |
---|---|
Cheapest round-trip ticket price | $295 |
Off-season for travel | May |
Peak season for travel | June |
Flight distance | 438.83km |
Average flight time | 1 hour 7 minutes |
Popular airline | American Airlines |
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