$266 Find Cheap Flights from Medellin to San Francisco

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Find cheap flights from Medellin to San Francisco starting at $266.

Book one-way or return flights from Medellin to San Francisco from as little as $266. Choose from the popular airlines below and book your flight today!

One way
Round-trip

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Searching for the best last minute flight from Medellin to San Francisco? Find one-way or return flights that are affordable and fit your itinerary.

Trip.com monitors the ticket fares of flights from Medellin to San Francisco. Stay updated on price trends and snag the best deals for your upcoming trip.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Find cheap airlines flights from Medellin to San Francisco

View airlines operating flights from Medellin to San Francisco. Compare prices, find the option that best suits your travel needs, and enjoy a comfortable journey with a trusted airline.

Spirit Airlines

From $217

JetSMART Airlines

From $235

Avianca

From $242

Copa Airlines

From $258

Jetblue Airways

From $271

LATAM Airlines

From $284

American Airlines

From $352

Delta Air Lines

From $366

Aeromexico

From $400

United Airlines

From $491

ANA airlines

Find more flights and airlines

Find cheap flights from Medellin to San Francisco by different airports

Discover different routes, airlines, and transfers and find the best alternative flights for your journey from Medellin to San Francisco.

Cheapest
MDE
01:26
23h 24m
2 transfer
SFO
22:50
Jose Marie Cordova Airport - San Francisco International Airport
Fri, May 3Spirit Airlines
$217
MDE
01:26
23h 24m
2 transfer
SFO
22:50
Jose Marie Cordova Airport - San Francisco International Airport
Fri, May 3Spirit Airlines
$217
Find More Flights

Frequently Asked Questions

When are flight tickets from Medellin (MDE) to San Francisco (SFO) the cheapest?
Airlines adjust prices for flights from Medellin to San Francisco based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.
How much do flights from Medellin (MDE) to San Francisco (SFO) cost?
According to Trip.com's data, the lowest price is around $646.
What is the transportation method from the main airport to downtown in San Francisco?
- The distance from San Francisco International Airport to downtown is about 17km. It takes about 30 minutes by taxi.

How to find a cheap flight from Medellin to San Francisco

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Medellin to San Francisco. Book your flights at the right time and save more.

Book Early

Once prices are gone, they're gone. Lock in deals while you can!

Compare Flight Prices

Compare prices on travel agency and airline websites.

Look Out for Deals

Check airline and travel agency websites for latest flight deals

Check One-way Fares

Buying two cheap one-way flights can sometimes be a better deal than a round-trip.

Try Different Dates

Flying during the week, early in the morning, or late at night can help save money.

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