Cheap flight from Mexico City to Medellin from $146

Frequently Asked Questions

• Which airlines offer direct flights from Mexico City to Medellin?

  At the moment, you can catch a nonstop flight from Mexico City to Medellin with the following airlines, including: avianca Copa Airlines Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.

• How long does it take to fly from Mexico City (MEX) to Medellin (MDE) and what is the distance?

  It takes around 4 hours 25 minutes to fly from Mexico City (MEX) to Medellin (MDE).

• When is the best time to book flights from Mexico City to Medellin?

  By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Mexico City to Medellin is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.

• How many flights are there per week from Mexico City to Medellin?

  Based on Trip.com data in the past 4 weeks, there is 13 flight per week flying from Mexico City to Medellin. You can check the weekly schedule for popular airlines on this route below: avianca: S/M/T/W/T/F/S -- AV235 (05:35)

• When are flight tickets from Mexico City (MEX) to Medellin (MDE) the cheapest?

  The cheapest months to fly from Mexico City to Medellin is September, when demand for travel is lower.

• Which upcoming date is cheapest to fly from Mexico City to Medellin on?

  After crunching the numbers on our November flight calendar, it's currently cheapest to fly from Mexico City to Medellin on November 17, 2025 with Arajet Airline, with prices starting at $130.

• Which airports can I fly to for Medellin from Mexico City?

  You can land at any one of the following hubs in Medellin, with Mexico City International Airport to Jose Maria Cordova International Airport (MEX-MDE) is by far the most common option on this route: Jose Maria Cordova International Airport (MDE) Olaya Herrera Airport (EOH).

• Is there any time difference between Mexico City and Medellin?

  The time difference between Medellin and Mexico City is 1h.

• How do I change or cancel my ticket from Mexico City to Medellin?

  Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.