$148 Find Cheap Flights from Mexico City to Panama City

App

Help

USD

Search Bookings

Trip.com

Flights

Flights to Panama

Flights to Panama City

Flights from Mexico City to Panama City

Hotels in Panama City

Worldwide Coverage

Flights to over 5,000 cities

One-stop Service Guarantee

Price guaranteed upon confirmed payment, booking guaranteed once tickets issued

Secure Payment

Convenient & reliable booking and payment system

Find cheap flights from Mexico City to Panama City starting at $148.

Book one-way or return flights from Mexico City to Panama City from as little as $148. Choose from the popular airlines below and book your flight today!

One way
Round-trip

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Searching for the best last minute flight from Mexico City to Panama City? Find one-way or return flights that are affordable and fit your itinerary.

Trip.com monitors the ticket fares of flights from Mexico City to Panama City. Stay updated on price trends and snag the best deals for your upcoming trip.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Find cheap airlines flights from Mexico City to Panama City

View airlines operating flights from Mexico City to Panama City. Compare prices, find the option that best suits your travel needs, and enjoy a comfortable journey with a trusted airline.

Avianca

From $148

Volaris El Salvador

From $188

Volaris

From $194

Volaris Costa Rica

From $195

Aeromexico

From $208

Viva Aerobus

From $254

American Airlines

From $361

LATAM Airlines

From $439

Copa Airlines

From $479

United Airlines

From $479

ANA airlines

Find more flights and airlines

Find cheap flights from Mexico City to Panama City by different airports

Discover different routes, airlines, and transfers and find the best alternative flights for your journey from Mexico City to Panama City.

Cheapest
MEX
00:40
15h 5m
1 transfer
PTY
16:45
Mexico City International Airport - Tocumen International Airport
Thu, May 2Avianca
$148
NLU
18:40
14h 45m
1 transfer
PTY
10:25
Felipe Ángeles International Airport - Tocumen International Airport
Sun, Jun 2Viva Aerobus
$254
TLC
06:30
13h 15m
2 transfer
PTY
20:45
Toluca Airport - Tocumen International Airport
Mon, May 6Viva Aerobus
$280
TLC
06:30
13h 15m
2 transfer
PTY
20:45
Toluca Airport - Tocumen International Airport
Mon, May 6Viva Aerobus
$280
Find More Flights

Frequently Asked Questions

When are flight tickets from Mexico City (MEX) to Panama City (PTY) the cheapest?
Airlines adjust prices for flights from Mexico City to Panama City based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.
How much do flights from Mexico City (MEX) to Panama City (PTY) cost?
According to Trip.com's data, the lowest price is around $653.
How long does it take to fly from Mexico City (MEX) to Panama City (PTY) and what is the distance?
It takes around 3 hours 46 minutes to fly from Mexico City (MEX) to Panama City (PTY).
What is the transportation method from the main airport to downtown in Panama City?
- The distance from Tocumen International Airport to downtown is about 16km. It takes about 30 minutes by taxi.
- The distance from Albrook "Marcos A. Gelabert" International Airport to downtown is about 5km. It takes about 20 minutes by taxi.
What are the most popular airlines that fly from Mexico City (MEX) to Panama City (PTY)?
Airlines with flights from Mexico City (MEX) to Panama City (PTY): Copa Airlines and Emirates.

How to find a cheap flight from Mexico City to Panama City

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Mexico City to Panama City. Book your flights at the right time and save more.

Book Early

Once prices are gone, they're gone. Lock in deals while you can!

Compare Flight Prices

Compare prices on travel agency and airline websites.

Look Out for Deals

Check airline and travel agency websites for latest flight deals

Check One-way Fares

Buying two cheap one-way flights can sometimes be a better deal than a round-trip.

Try Different Dates

Flying during the week, early in the morning, or late at night can help save money.

Use the Trip.com App

Save up to £10 per person when booking your flights on Trip.com

Mexico City to Panama City Flight Information

Cheapest nonstop flight price	$148
Cheapest round-trip ticket price	$391
Off-season for travel	February
Peak season for travel	October
Flight distance	2,403.84km
Average flight time	3 hours 46 minutes
Popular airline	American Airlines