$521 Find Cheap Flights from Santiago to Brussels

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Flights from Santiago to Brussels

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Find cheap flights from Santiago to Brussels starting at $521.

Book one-way or return flights from Santiago to Brussels from as little as $521. Choose from the popular airlines below and book your flight today!

One way
Round-trip

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Searching for the best last minute flight from Santiago to Brussels? Find one-way or return flights that are affordable and fit your itinerary.

Trip.com monitors the ticket fares of flights from Santiago to Brussels. Stay updated on price trends and snag the best deals for your upcoming trip.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Find cheap airlines flights from Santiago to Brussels

View airlines operating flights from Santiago to Brussels. Compare prices, find the option that best suits your travel needs, and enjoy a comfortable journey with a trusted airline.

Avianca

From $488

Iberia

From $521

JetSMART Airlines

From $525

Sky Airline

From $534

Vueling Airlines

From $565

LATAM Airlines

From $566

Copa Airlines

From $694

Aerolineas Argentinas

From $722

Air France

From $839

Air Canada

From $907

ANA airlines

Find more flights and airlines

Find cheap flights from Santiago to Brussels by different airports

Discover different routes, airlines, and transfers and find the best alternative flights for your journey from Santiago to Brussels.

Cheapest
SCL
06:10
44h 50m
2 transfer
BRU
09:00
Arturo Merino Benitez Airport - Brussels National Airport
Thu, Jul 4Avianca
$488
SCL
23:55
40h 35m
2 transfer
CRL
22:30
Arturo Merino Benitez Airport - Brussels South Charleroi Airport
Fri, Jun 28Avianca
$732
SCL
23:55
40h 35m
2 transfer
CRL
22:30
Arturo Merino Benitez Airport - Brussels South Charleroi Airport
Fri, Jun 28Avianca
$732
Find More Flights

Frequently Asked Questions

When are flight tickets from Santiago (SCL) to Brussels (BRU) the cheapest?
Airlines adjust prices for flights from Santiago to Brussels based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.
How much do flights from Santiago (SCL) to Brussels (BRU) cost?
According to Trip.com's data, the lowest price is around $1,312.
What is the transportation method from the main airport to downtown in Brussels?
- The distance from Brussels National Airport to downtown is about 10km. It takes about 30 minutes by taxi.
- The distance from Brussels South Charleroi Airport to downtown is about 43km. It takes about 1 hour by taxi.

How to find a cheap flight from Santiago to Brussels

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Santiago to Brussels. Book your flights at the right time and save more.

Book Early

Once prices are gone, they're gone. Lock in deals while you can!

Compare Flight Prices

Compare prices on travel agency and airline websites.

Look Out for Deals

Check airline and travel agency websites for latest flight deals

Check One-way Fares

Buying two cheap one-way flights can sometimes be a better deal than a round-trip.

Try Different Dates

Flying during the week, early in the morning, or late at night can help save money.

Use the Trip.com App

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