$110 Find Cheap Flights from Santiago to Santa Cruz

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Find cheap flights from Santiago to Santa Cruz starting at $110.

Book one-way or return flights from Santiago to Santa Cruz from as little as $110. Choose from the popular airlines below and book your flight today!

One way
Round-trip

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Searching for the best last minute flight from Santiago to Santa Cruz? Find one-way or return flights that are affordable and fit your itinerary.

Trip.com monitors the ticket fares of flights from Santiago to Santa Cruz. Stay updated on price trends and snag the best deals for your upcoming trip.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Find cheap airlines flights from Santiago to Santa Cruz

View airlines operating flights from Santiago to Santa Cruz. Compare prices, find the option that best suits your travel needs, and enjoy a comfortable journey with a trusted airline.

LATAM Airlines

From $110

Aerolineas Argentinas

From $138

JetSMART Airlines

From $161

Sky Airline

From $192

JetSmart Airlines

From $229

Avianca

From $230

Copa Airlines

From $295

KLM

From $368

ANA airlines

Find more flights and airlines

Find cheap flights from Santiago to Santa Cruz by different airports

Discover different routes, airlines, and transfers and find the best alternative flights for your journey from Santiago to Santa Cruz.

Cheapest
SCL
19:55
8h 45m
1 transfer
VVI
04:40
Arturo Merino Benitez Airport - Viru Viru International Airport
Thu, Jun 6LATAM Airlines
$110
SCL
19:55
8h 45m
1 transfer
VVI
04:40
Arturo Merino Benitez Airport - Viru Viru International Airport
Thu, Jun 6LATAM Airlines
$110
Find More Flights

Frequently Asked Questions

When are flight tickets from Santiago (SCL) to Santa Cruz (SRZ) the cheapest?
Airlines adjust prices for flights from Santiago to Santa Cruz based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.
How much do flights from Santiago (SCL) to Santa Cruz (SRZ) cost?
According to Trip.com's data, the lowest price is around $362.
How long does it take to fly from Santiago (SCL) to Santa Cruz (SRZ) and what is the distance?
It takes around 4 hours 1 minute to fly from Santiago (SCL) to Santa Cruz (SRZ).
What is the transportation method from the main airport to downtown in Santa Cruz?
- The distance from Viru Viru International Airport to downtown is about 17km. It takes about 30 minutes by taxi.
What are the most popular airlines that fly from Santiago (SCL) to Santa Cruz (SRZ)?
Airlines with flights from Santiago (SCL) to Santa Cruz (SRZ): LATAM Airlines.

How to find a cheap flight from Santiago to Santa Cruz

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Santiago to Santa Cruz. Book your flights at the right time and save more.

Book Early

Once prices are gone, they're gone. Lock in deals while you can!

Compare Flight Prices

Compare prices on travel agency and airline websites.

Look Out for Deals

Check airline and travel agency websites for latest flight deals

Check One-way Fares

Buying two cheap one-way flights can sometimes be a better deal than a round-trip.

Try Different Dates

Flying during the week, early in the morning, or late at night can help save money.

Use the Trip.com App

Save up to £10 per person when booking your flights on Trip.com

Santiago to Santa Cruz Flight Information

Cheapest nonstop flight price	$109
Cheapest round-trip ticket price	$249
Off-season for travel	June
Peak season for travel	October
Flight distance	1,893.1km
Average flight time	4 hours 1 minute
Popular airline	LATAM Airlines