$179 Cheap Flights from Buffalo to Panama City
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Flights from Buffalo to Panama City
Cheap flight deals from Buffalo to Panama City Starting at $179
We've found these cheap flights for you. You can book one-way or round-trip flight tickets.
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Round-trip
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One way
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BUF 6:00 AM14h 31m1 stopsPTY 7:31 PMBuffalo - Panama City | Sun, Mar 30 | United Airlines
PTY 9:45 AM13h 10m1 stopsBUF 11:55 PMPanama City - Buffalo | Sat, Apr 5 | United Airlines$450 $61727% OFF27% OFF$617 $450 -
BUF 6:00 AM7h 48m1 stopsPTY 12:48 PMBuffalo - Panama City | Sun, May 18 | Delta Air Lines
PTY 2:13 PM8h 42m1 stopsBUF 11:55 PMPanama City - Buffalo | Wed, May 21 | Delta Air Lines$452 $61727% OFF27% OFF$617 $452 -
BUF 6:00 AM7h 48m1 stopsPTY 12:48 PMBuffalo - Panama City | Tue, May 20 | Delta Air Lines
PTY 2:13 PM8h 42m1 stopsBUF 11:55 PMPanama City - Buffalo | Thu, May 22 | Delta Air Lines$452 $61727% OFF27% OFF$617 $452
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BUF 6:00 AM23h 5m1 stopsPTY 4:05 AMBuffalo - Panama City | Tue, Apr 1 | United Airlines
PTY 10:55 PM23h 49m1 stopsBUF 11:44 PMPanama City - Buffalo | Thu, Apr 3 | United Airlines$45426% OFF$617 $454
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BUF 6:00 AM23h 5m1 stopsPTY 4:05 AMBuffalo - Panama City | Fri, May 9 | United Airlines
PTY 10:55 PM24h 2m1 stopsBUF 11:57 PMPanama City - Buffalo | Fri, May 16 | United Airlines$45526% OFF$617 $455
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BUF 6:00 AM14h 31m1 stopsPTY 7:31 PMBuffalo - Panama City | Sat, May 10 | United Airlines
PTY 9:45 AM13h 12m1 stopsBUF 11:57 PMPanama City - Buffalo | Sat, May 17 | United Airlines$45626% OFF$617 $456
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BUF 6:00 AM23h 5m1 stopsPTY 4:05 AMBuffalo - Panama City | Sat, May 17 | United Airlines
PTY 9:45 AM13h 12m1 stopsBUF 11:57 PMPanama City - Buffalo | Tue, May 20 | United Airlines$45726% OFF$617 $457
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BUF 6:00 AM14h 31m1 stopsPTY 7:31 PMBuffalo - Panama City | Sat, Apr 5 | United Airlines
PTY 9:45 AM12h 59m1 stopsBUF 11:44 PMPanama City - Buffalo | Fri, Apr 11 | United Airlines$46026% OFF$617 $460
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BUF 6:00 AM23h 5m1 stopsPTY 4:05 AMBuffalo - Panama City | Mon, Apr 7 | United Airlines
PTY 9:45 AM12h 59m1 stopsBUF 11:44 PMPanama City - Buffalo | Mon, Apr 14 | United Airlines$46325% OFF$617 $463
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BUF 6:00 AM23h 5m1 stopsPTY 4:05 AMBuffalo - Panama City | Wed, Apr 16 | United Airlines
PTY 10:55 PM23h 49m1 stopsBUF 11:44 PMPanama City - Buffalo | Wed, Apr 23 | United Airlines$46325% OFF$617 $463
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BUF 1:00 PM17h 25m1 stopsPTY Invalid DateBuffalo - Panama City | Sat, Mar 29 | Normal Airline
PTY 3:00 PM6hNonstopBUF 4:00 PMPanama City - Buffalo | Mon, Mar 31 | Normal AirlineFind More FlightsFind More Flights
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BUF 6:00 AM14h 31m1 stopsPTY 7:31 PMBuffalo - Panama City | Sun, Mar 30 | United Airlines$179 $26532% OFF32% OFF$265 $179
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BUF 1:20 PM15h 52m1 stopsPTY 4:12 AMBuffalo - Panama City | Fri, Mar 28 | United Airlines$182 $26531% OFF31% OFF$265 $182
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BUF 7:21 PM9h 44m1 stopsPTY 4:05 AMBuffalo - Panama City | Sat, Mar 29 | United Airlines$185 $26530% OFF30% OFF$265 $185
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BUF 6:00 AM14h 31m1 stopsPTY 7:31 PMBuffalo - Panama City | Mon, Mar 31 | United Airlines$18530% OFF$265 $185
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BUF 6:00 AM14h 31m1 stopsPTY 7:31 PMBuffalo - Panama City | Fri, May 9 | United Airlines$19327% OFF$265 $193
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BUF 6:00 AM14h 31m1 stopsPTY 7:31 PMBuffalo - Panama City | Wed, May 7 | United Airlines$19427% OFF$265 $194
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BUF 6:00 AM14h 31m1 stopsPTY 7:31 PMBuffalo - Panama City | Sat, Apr 5 | United Airlines$19626% OFF$265 $196
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BUF 8:50 AM20h 15m1 stopsPTY 4:05 AMBuffalo - Panama City | Fri, Apr 18 | United Airlines$19825% OFF$265 $198
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BUF 6:00 AM23h 5m1 stopsPTY 4:05 AMBuffalo - Panama City | Tue, Apr 8 | United Airlines$19825% OFF$265 $198
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BUF 6:45 PM19h 10m1 stopsPTY 12:55 PMBuffalo - Panama City | Wed, Apr 16 | Delta Air Lines$19925% OFF$265 $199
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BUF 1:00 PM17h 25m1 stopsPTY Invalid DateBuffalo - Panama City | Sat, Mar 29 | Normal AirlineFind More FlightsFind More Flights
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Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.
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Frequently Asked Questions
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When are flight tickets from Buffalo (BUF) to Panama City (PTY) the cheapest?
Airlines adjust prices for flights from Buffalo to Panama City based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays. -
How much do flights from Buffalo (BUF) to Panama City (PTY) cost?
According to Trip.com's data, the lowest price is around $642. -
What is the transportation method from the main airport to downtown in Panama City?
- The distance from Tocumen International Airport to downtown is about 16 km. It takes about 30 minutes by taxi.
- The distance from Albrook "Marcos A. Gelabert" International Airport to downtown is about 5 km. It takes about 20 minutes by taxi.
How to find a cheap flight from Buffalo to Panama City
Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Buffalo to Panama City. Book your flights at the right time and save more.
Be flexible with your travel dates to get the cheapest Buffalo to Panama City ticket.
Tap "Date" in the flight search bar to browse the calendar and find airfare from Buffalo to Panama City for the next six months in 2025. If you're looking to fly within the next three months, the lowest fare is $179 for a one-way ticket on Sun, Mar 30.
Compare cheap Buffalo to Panama City flight deals from hundreds of airlines.
Our powerful search system compares prices from over 500 airlines. So you can find the cheapest flights from Buffalo to Panama City. The most affordable airline currently operating on this route is United Airlines.
Set up a Price Alert to track fare drops.
Set up a Price Alert for your Buffalo to Panama City route to track ticket prices effortlessly—no need to check manually every day.
Don't miss out on cheap Buffalo to Panama City flight deals and promo codes.
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Book early or wait unitl the last minute to fine the best fares.
It's always better to book early! Airlines typically release their lowest fares about a year before departure, so check as soon as flights become available. If you miss that window, you may still find great deals closer to your travel date.
Search for flights on the go.
For the best booking experience on the go, download Trip.com and search for cheap flights from Buffalo to Panama City to access exclusive deals just for you.
Flight Info | Buffalo to Panama City
| Cheapest one-way flight price | $179 |
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| Off-season for travel | March |
| Peak season for travel | December |
| Flight distance | 3,778.53 km |
| Popular airline | United Airlines |
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