$222 Find Cheap Flights from Chicago to Panama City

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Find cheap flights from Chicago to Panama City starting at $222.

Book one-way or return flights from Chicago to Panama City from as little as $222. Choose from the popular airlines below and book your flight today!

One way
Round-trip

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Searching for the best last minute flight from Chicago to Panama City? Find one-way or return flights that are affordable and fit your itinerary.

Trip.com monitors the ticket fares of flights from Chicago to Panama City. Stay updated on price trends and snag the best deals for your upcoming trip.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Find cheap airlines flights from Chicago to Panama City

View airlines operating flights from Chicago to Panama City. Compare prices, find the option that best suits your travel needs, and enjoy a comfortable journey with a trusted airline.

Frontier Airlines

From $161

Spirit Airlines

From $178

United Airlines

From $199

Delta Air Lines

From $242

American Airlines

From $264

Southwest Airlines

From $282

Avianca

From $309

Copa Airlines

From $707

Aeromexico

From $726

Air Canada

From $1,053

ANA airlines

Find more flights and airlines

Find cheap flights from Chicago to Panama City by different airports

Discover different routes, airlines, and transfers and find the best alternative flights for your journey from Chicago to Panama City.

Cheapest
MDW
19:17
25h 28m
2 transfer
PTY
20:45
Midway International Airport - Tocumen International Airport
Wed, May 1Frontier Airlines
$161
ORD
07:27
26h 58m
2 transfer
PTY
10:25
O'Hare International Airport - Tocumen International Airport
Tue, May 7Spirit Airlines
$178
RFD
08:36
11h 51m
1 transfer
PTY
20:27
Chicago Rockford International Airport - Tocumen International Airport
Fri, May 24Allegiant Air
$1,555
RFD
08:36
11h 51m
1 transfer
PTY
20:27
Chicago Rockford International Airport - Tocumen International Airport
Fri, May 24Allegiant Air
$1,555
Find More Flights

Frequently Asked Questions

When are flight tickets from Chicago (CHI) to Panama City (PTY) the cheapest?
Airlines adjust prices for flights from Chicago to Panama City based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.
How much do flights from Chicago (CHI) to Panama City (PTY) cost?
According to Trip.com's data, the lowest price is around $703.
How long does it take to fly from Chicago (CHI) to Panama City (PTY) and what is the distance?
It takes around 5 hours 28 minutes to fly from Chicago (CHI) to Panama City (PTY).
What is the transportation method from the main airport to downtown in Panama City?
- The distance from Tocumen International Airport to downtown is about 16km. It takes about 30 minutes by taxi.
- The distance from Albrook "Marcos A. Gelabert" International Airport to downtown is about 5km. It takes about 20 minutes by taxi.
What are the most popular airlines that fly from Chicago (CHI) to Panama City (PTY)?
Airlines with flights from Chicago (CHI) to Panama City (PTY): United Airlines, EVA Air and Copa Airlines.

How to find a cheap flight from Chicago to Panama City

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Chicago to Panama City. Book your flights at the right time and save more.

Book Early

Once prices are gone, they're gone. Lock in deals while you can!

Compare Flight Prices

Compare prices on travel agency and airline websites.

Look Out for Deals

Check airline and travel agency websites for latest flight deals

Check One-way Fares

Buying two cheap one-way flights can sometimes be a better deal than a round-trip.

Try Different Dates

Flying during the week, early in the morning, or late at night can help save money.

Use the Trip.com App

Save up to £10 per person when booking your flights on Trip.com

Chicago to Panama City Flight Information

Cheapest nonstop flight price	$222
Cheapest round-trip ticket price	$432
Off-season for travel	January
Peak season for travel	October
Flight distance	3,744.48km
Average flight time	5 hours 28 minutes
Popular airline	American Airlines