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Flights from Cancun to Des Moines

Find cheap airlines flights from Cancun to Des Moines

You can choose from 1 airlines that fly from Cancun to Des Moines, including Delta Air Lines, Frontier Airlines has lowest fares on this route.
Delta Air Lines logo Delta Air Lines
Airlines are determined based on actual purchased flight tickets from Cancun to Des Moines according to previous 12 months data from Trip.com.

Find flight deals from Cancun to Des Moines for the next 3 months. Book one way flights from $202 or round trip flights from $387.

      • CUN 12:11 PM
        9h 21m
        1 stop
        DSM 9:32 PM
        Cancun - Des Moines | Wed, Apr 29 | United Airlines
        DSM 5:30 AM
        7h 28m
        1 stop
        CUN 12:58 PM
        Des Moines - Cancun | Wed, May 6 | United Airlines
        $387 $810
        52% off
        52% off
        $810 $387
      • CUN 3:43 PM
        7h 59m
        1 stop
        DSM 11:42 PM
        Cancun - Des Moines | Thu, Apr 23 | United Airlines
        DSM 5:30 AM
        7h 28m
        1 stop
        CUN 12:58 PM
        Des Moines - Cancun | Tue, Apr 28 | United Airlines
        $431 $810
        47% off
        47% off
        $810 $431
      • CUN 7:51 AM
        14h 52m
        1 stop
        DSM 10:43 PM
        Cancun - Des Moines | Wed, Apr 1 | United Airlines
        DSM 8:20 AM
        10h 59m
        1 stop
        CUN 7:19 PM
        Des Moines - Cancun | Wed, Apr 8 | United Airlines
        $432 $810
        47% off
        47% off
        $810 $432
      • CUN 11:00 AM
        6h 45m
        1 stop
        DSM 5:45 PM
        Cancun - Des Moines | Wed, Apr 29 | Aeromexico
        DSM 5:45 AM
        8h 16m
        1 stop
        CUN 2:01 PM
        Des Moines - Cancun | Wed, May 6 | Aeromexico
        $439
        46% off
        $810 $439
      • CUN 12:55 PM
        10h 22m
        1 stop
        DSM 11:17 PM
        Cancun - Des Moines | Thu, Apr 16 | United Airlines
        DSM 8:20 AM
        25h 46m
        1 stop
        CUN 10:06 AM
        Des Moines - Cancun | Fri, Apr 24 | United Airlines
        $445
        45% off
        $810 $445
      • CUN 5:30 AM
        17h 14m
        1 stop
        DSM 10:44 PM
        Cancun - Des Moines | Wed, Mar 25 | United Airlines
        DSM 6:12 AM
        27h 54m
        1 stop
        CUN 10:06 AM
        Des Moines - Cancun | Sat, Mar 28 | United Airlines
        $448
        45% off
        $810 $448
      • CUN 3:15 PM
        7h 19m
        1 stop
        DSM 10:34 PM
        Cancun - Des Moines | Thu, Apr 16 | Aeromexico
        DSM 2:44 PM
        5h 31m
        1 stop
        CUN 8:15 PM
        Des Moines - Cancun | Fri, Apr 24 | Aeromexico
        $508
        37% off
        $810 $508
      • CUN 12:35 PM
        8h 4m
        1 stop
        DSM 8:39 PM
        Cancun - Des Moines | Thu, Apr 23 | Delta Air Lines
        DSM 7:00 AM
        7h 4m
        1 stop
        CUN 2:04 PM
        Des Moines - Cancun | Thu, Apr 30 | Aeromexico
        $533
        34% off
        $810 $533
      • CUN 8:00 AM
        8h 33m
        1 stop
        DSM 4:33 PM
        Cancun - Des Moines | Wed, Apr 1 | Aeromexico
        DSM 5:35 AM
        14h 39m
        1 stop
        CUN 8:14 PM
        Des Moines - Cancun | Wed, Apr 8 | Aeromexico
        $549
        32% off
        $810 $549
      • CUN 7:39 AM
        6h 39m
        1 stop
        DSM 2:18 PM
        Cancun - Des Moines | Wed, Mar 18 | United Airlines
        DSM 5:30 AM
        7h 48m
        1 stop
        CUN 1:18 PM
        Des Moines - Cancun | Wed, Mar 25 | United Airlines
        $599
        26% off
        $810 $599
      • CUN 1:00 PM
        17h 25m
        1 stop
        DSM Invalid Date
        Cancun - Des Moines | Fri, Mar 20 | Normal Airline
        DSM 3:00 PM
        6h
        Nonstop
        CUN 4:00 PM
        Des Moines - Cancun | Sun, Mar 22 | Normal Airline
        Find more flights
        Find more flights
      • CUN 10:40 AM
        12h 49m
        1 stop
        DSM 11:29 PM
        Cancun - Des Moines | Tue, Apr 14 | Frontier Airlines
        $202 $406
        50% off
        50% off
        $406 $202
      • CUN 10:08 AM
        9h 8m
        1 stop
        DSM 7:16 PM
        Cancun - Des Moines | Mon, Mar 30 | Frontier Airlines
        $227 $406
        44% off
        44% off
        $406 $227
      • CUN 10:08 AM
        9h 8m
        1 stop
        DSM 7:16 PM
        Cancun - Des Moines | Fri, Mar 27 | Frontier Airlines
        $227 $406
        44% off
        44% off
        $406 $227
      • CUN 2:49 PM
        7h 54m
        1 stop
        DSM 10:43 PM
        Cancun - Des Moines | Tue, Apr 28 | United Airlines
        $236
        42% off
        $406 $236
      • CUN 12:35 PM
        8h 4m
        1 stop
        DSM 8:39 PM
        Cancun - Des Moines | Thu, Apr 23 | Delta Air Lines
        $257
        37% off
        $406 $257
      • CUN 2:18 PM
        20h 12m
        1 stop
        DSM 10:30 AM
        Cancun - Des Moines | Tue, Mar 24 | United Airlines
        $269
        34% off
        $406 $269
      • CUN 11:00 AM
        11h 34m
        1 stop
        DSM 10:34 PM
        Cancun - Des Moines | Tue, Apr 28 | Aeromexico
        $279
        31% off
        $406 $279
      • CUN 3:54 PM
        21h 35m
        1 stop
        DSM 1:29 PM
        Cancun - Des Moines | Thu, Apr 23 | Frontier Airlines
        $281
        31% off
        $406 $281
      • CUN 2:00 PM
        7h 8m
        1 stop
        DSM 9:08 PM
        Cancun - Des Moines | Tue, Apr 14 | Delta Air Lines
        $300
        26% off
        $406 $300
      • CUN 12:10 PM
        25h 1m
        1 stop
        DSM 1:11 PM
        Cancun - Des Moines | Tue, Apr 14 | American Airlines
        $300
        26% off
        $406 $300
      • CUN 1:00 PM
        17h 25m
        1 stop
        DSM Invalid Date
        Cancun - Des Moines | Fri, Mar 20 | Normal Airline
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        Find more flights

Displayed flight fares from Cancun to Des Moines are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

Flight Info | Cancun to Des Moines

The distance between Cancun and Des Moines is approximately 2,366.53 km. Based on Trip.com's data travel demand peaks in December. The off-season for travel is September.

Cheapest one-way flight price$202
Cheapest round-trip ticket price$387
Off-season for travelSeptember
Peak season for travelDecember
Flight distance2,366.53 km
Popular airlineDelta Air Lines
Flight statistics for the Cancun–Des Moines route are based on aggregated booking data from Trip.com over the past 12 months.

Frequently Asked Questions

  • What are the cheapest flights from Cancun to Des Moines (CUN-DSM)?

    Based on Trip.com data, Frontier Airlines offers one-way fares as low as $202 on Cheapest nonstop routes (e.g. CUN to DSM on Tue, Apr 14), while United Airlines offers Cheapest nonstop round-trips from $387 departing on Wed, Apr 29 and returning on Wed, May 6.
  • At the moment, several airlines serve connecting flights from Cancun to Des Moines, including: Delta Air Lines Selected airlines are based on historical data collected from flight bookings made by users on Trip.com within the last 90 days.
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Cancun to Des Moines is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • To find best deals on flights from Cancun to Des Moines, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Tue, Apr 14, with one-way flights priced at just $202.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is Frontier Airlines.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Des Moines travel is around December.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Cancun to Des Moines is September, when demand for travel is lower.
  • After crunching the numbers on our March flight calendar, it's currently cheapest to fly from Cancun to Des Moines on March 30, 2026 with Frontier Airlines, with prices starting at $227.
  • You can land at any one of the following hubs in Des Moines, with Cancun International Airport to Des Moines International Airport (CUN-DSM) is by far the most common option on this route: Des Moines International Airport (DSM).
  • The time difference between Des Moines and Cancun is 1h.
  • Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

Trip.com airline insights on flights from Cancun to Des Moines

Which airlines offer the cheapest nonstop flights from Cancun to Des Moines?

Data is based on the average price of all nonstop flights from Cancun to Des Moines on Trip.com in the past 12 months.

Based on Trip.com data from the past 12 months, Aeromexico offers the cheapest nonstop flights from Cancun to Des Moines, with an average price of $229.

$223
$229
$236
$242
$248
Aeromexico
$229
Aeromexico
Delta Air Lines
$247
Delta Air Lines
United Airlines
$248
United Airlines

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Note: Prices shown on this page are estimated lowest price and include all taxes and fees found in the last 24 hours.

Book with no extra fees

Prices displayed in this page are all-inclusive prices (incl. taxes, fuel surcharge, civil aviation development fund, etc) with all fees confirmed before payment. Fees for luggage, meals, WLAN, or other additional services are also included as shown in the flight cards.

Real-time pricing updates

Prices, availability, and travel information on this page were updated within last 24 hours—even in real-time. The more popular the route, the more precise the data.

Change & Cancellation Policy

Trip.com displays flight cancellation and change policies for each flight ticket during the booking process, including fees and applicable conditions. Please check the following scenarios:
Voluntary cancellation/change:
To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy.
Cancellation/change due to a flight schedule change:
If the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.