$107 Find Cheap Flights from Charleston to Knoxville

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Find cheap flights from Charleston to Knoxville starting at $107.

Book one-way or return flights from Charleston to Knoxville from as little as $107. Choose from the popular airlines below and book your flight today!

One way
Round-trip

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Searching for the best last minute flight from Charleston to Knoxville? Find one-way or return flights that are affordable and fit your itinerary.

Trip.com monitors the ticket fares of flights from Charleston to Knoxville. Stay updated on price trends and snag the best deals for your upcoming trip.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Find cheap airlines flights from Charleston to Knoxville

View airlines operating flights from Charleston to Knoxville. Compare prices, find the option that best suits your travel needs, and enjoy a comfortable journey with a trusted airline.

Spirit Airlines

From $68

Frontier Airlines

From $78

Breeze Airways

From $107

United Airlines

From $222

Delta Air Lines

From $235

American Airlines

From $269

ANA airlines

Find more flights and airlines

Find cheap flights from Charleston to Knoxville by different airports

Discover different routes, airlines, and transfers and find the best alternative flights for your journey from Charleston to Knoxville.

Cheapest
CHS
12:52
18h 31m
2 transfer
TYS
07:23
Charleston International Airport - Mcghee Tyson Airport
Wed, May 8Spirit Airlines
$68
CHS
12:52
18h 31m
2 transfer
TYS
07:23
Charleston International Airport - Mcghee Tyson Airport
Wed, May 8Spirit Airlines
$68
Find More Flights

Frequently Asked Questions

When are flight tickets from Charleston (CHS) to Knoxville (TYS) the cheapest?
Airlines adjust prices for flights from Charleston to Knoxville based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.
How much do flights from Charleston (CHS) to Knoxville (TYS) cost?
According to Trip.com's data, the lowest price is around $482.

How to find a cheap flight from Charleston to Knoxville

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Charleston to Knoxville. Book your flights at the right time and save more.

Book Early

Once prices are gone, they're gone. Lock in deals while you can!

Compare Flight Prices

Compare prices on travel agency and airline websites.

Look Out for Deals

Check airline and travel agency websites for latest flight deals

Check One-way Fares

Buying two cheap one-way flights can sometimes be a better deal than a round-trip.

Try Different Dates

Flying during the week, early in the morning, or late at night can help save money.

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