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Flights from Madrid to Panama City
Cheap flight deals from Madrid to Panama City
We've found these cheap flights for you. You can book one-way or round-trip flight tickets.
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Round-trip
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One way
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Cheapest nonstopMAD 3:05 PM10h 35mNonstopPTY 6:40 PMMadrid - Panama City | Wed, Apr 2 | Air EuropaPTY 8:25 PM9h 50mNonstopMAD 1:15 PMPanama City - Madrid | Wed, Apr 9 | Air Europa$521 $63718% OFF18% OFF$637 $521
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MAD 3:05 PM10h 35mNonstopPTY 6:40 PMMadrid - Panama City | Wed, Apr 9 | Air EuropaPTY 8:25 PM9h 50mNonstopMAD 1:15 PMPanama City - Madrid | Mon, Apr 14 | Air Europa$541 $63715% OFF15% OFF$637 $541
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MAD 3:05 PM10h 35mNonstopPTY 6:40 PMMadrid - Panama City | Sat, Apr 5 | Air EuropaPTY 8:25 PM9h 50mNonstopMAD 1:15 PMPanama City - Madrid | Sun, Apr 13 | Air Europa$541 $63715% OFF15% OFF$637 $541
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MAD 3:05 PM10h 35mNonstopPTY 6:40 PMMadrid - Panama City | Tue, Apr 1 | Air EuropaPTY 8:25 PM9h 50mNonstopMAD 1:15 PMPanama City - Madrid | Wed, Apr 9 | Air Europa$54614% OFF$637 $546
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MAD 3:05 PM10h 35mNonstopPTY 6:40 PMMadrid - Panama City | Tue, Apr 8 | Air EuropaPTY 8:25 PM9h 50mNonstopMAD 1:15 PMPanama City - Madrid | Sun, Apr 13 | Air Europa$54814% OFF$637 $548
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MAD 3:05 PM10h 35mNonstopPTY 6:40 PMMadrid - Panama City | Mon, Apr 14 | Air EuropaPTY 8:25 PM9h 50mNonstopMAD 1:15 PMPanama City - Madrid | Wed, Apr 16 | Air Europa$55613% OFF$637 $556
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MAD 3:05 PM10h 35mNonstopPTY 6:40 PMMadrid - Panama City | Mon, Apr 21 | Air EuropaPTY 8:25 PM9h 50mNonstopMAD 1:15 PMPanama City - Madrid | Mon, Apr 28 | Air Europa$57210% OFF$637 $572
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MAD 5:30 PM13h 40m1 stopsPTY 12:10 AMMadrid - Panama City | Fri, Apr 4 | aviancaPTY 10:05 PM18h 25m1 stopsMAD 11:30 PMPanama City - Madrid | Sun, Apr 6 | avianca$55513% OFF$637 $555
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MAD 9:40 AM18h 30m1 stopsPTY 9:10 PMMadrid - Panama City | Mon, Apr 7 | aviancaPTY 3:25 AM13h 5m1 stopsMAD 11:30 PMPanama City - Madrid | Tue, Apr 15 | avianca$55912% OFF$637 $559
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MAD 6:00 AM17h 50m1 stopsPTY 4:50 PMMadrid - Panama City | Mon, May 26 | KLMPTY 7:55 PM13h 50m1 stopsMAD 4:45 PMPanama City - Madrid | Mon, Jun 2 | Air France$5809% OFF$637 $580
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MAD 1:00 PM17h 25m1 stopsPTY Invalid DateMadrid - Panama City | Wed, Apr 2 | Normal AirlinePTY 3:00 PM6hNonstopMAD 4:00 PMPanama City - Madrid | Fri, Apr 4 | Normal AirlineFind More FlightsFind More Flights
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Cheapest nonstopMAD 3:05 PM10h 35mNonstopPTY 6:40 PMMadrid - Panama City | Sun, May 11 | Air Europa$362 $40711% OFF11% OFF$407 $362
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MAD 3:05 PM10h 35mNonstopPTY 6:40 PMMadrid - Panama City | Fri, May 16 | Air Europa$363 $40711% OFF11% OFF$407 $363
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MAD 3:05 PM10h 35mNonstopPTY 6:40 PMMadrid - Panama City | Mon, May 12 | Air Europa$363 $40711% OFF11% OFF$407 $363
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MAD 3:05 PM10h 35mNonstopPTY 6:40 PMMadrid - Panama City | Tue, Apr 1 | Air Europa$36710% OFF$407 $367
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MAD 3:05 PM10h 35mNonstopPTY 6:40 PMMadrid - Panama City | Mon, May 26 | Air Europa$36710% OFF$407 $367
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MAD 3:05 PM10h 35mNonstopPTY 6:40 PMMadrid - Panama City | Fri, Apr 25 | Air Europa$36810% OFF$407 $368
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MAD 3:05 PM10h 35mNonstopPTY 6:40 PMMadrid - Panama City | Fri, May 2 | Air Europa$36810% OFF$407 $368
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MAD 3:05 PM10h 35mNonstopPTY 6:40 PMMadrid - Panama City | Sat, May 3 | Air Europa$36810% OFF$407 $368
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MAD 3:05 PM10h 35mNonstopPTY 6:40 PMMadrid - Panama City | Mon, May 19 | Air Europa$3709% OFF$407 $370
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MAD 3:05 PM10h 35mNonstopPTY 6:40 PMMadrid - Panama City | Fri, May 9 | Air Europa$3719% OFF$407 $371
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MAD 1:00 PM17h 25m1 stopsPTY Invalid DateMadrid - Panama City | Wed, Apr 2 | Normal AirlineFind More FlightsFind More Flights
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Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.
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Find cheap airlines flights from Madrid to Panama City
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Frequently Asked Questions
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When are flight tickets from Madrid (MAD) to Panama City (PTY) the cheapest?
Airlines adjust prices for flights from Madrid to Panama City based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays. -
How much do flights from Madrid (MAD) to Panama City (PTY) cost?
According to Trip.com's data, the lowest price is around $1,015. -
How long does it take to fly from Madrid (MAD) to Panama City (PTY) and what is the distance?
It takes around 10 hours 37 minutes to fly from Madrid (MAD) to Panama City (PTY). -
What is the transportation method from the main airport to downtown in Panama City?
- The distance from Tocumen International Airport to downtown is about 16 km. It takes about 30 minutes by taxi.
- The distance from Albrook "Marcos A. Gelabert" International Airport to downtown is about 5 km. It takes about 20 minutes by taxi.
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What are the most popular airlines that fly from Madrid (MAD) to Panama City (PTY)?
Airlines with flights from Madrid (MAD) to Panama City (PTY): Air Europa, Copa Airlines, Iberia, Qatar Airways, British Airways, Etihad Airways, El Al and China Eastern Airlines.
How to find a cheap flight from Madrid to Panama City
Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Madrid to Panama City. Book your flights at the right time and save more.
Be flexible with your travel dates to get the cheapest Madrid to Panama City ticket.
Tap "Date" in the flight search bar to browse the calendar and find airfare from Madrid to Panama City for the next six months in 2025. If you're looking to fly within the next three months, the lowest fare is $362 for a one-way ticket on Sun, May 11.
Compare cheap Madrid to Panama City flight deals from hundreds of airlines.
Our powerful search system compares prices from over 500 airlines. So you can find the cheapest flights from Madrid to Panama City. The most affordable airline currently operating on this route is Air Europa.
Set up a Price Alert to track fare drops.
Set up a Price Alert for your Madrid to Panama City route to track ticket prices effortlessly—no need to check manually every day.
Don't miss out on cheap Madrid to Panama City flight deals and promo codes.
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Book early or wait unitl the last minute to fine the best fares.
It's always better to book early! Airlines typically release their lowest fares about a year before departure, so check as soon as flights become available. If you miss that window, you may still find great deals closer to your travel date.
Search for flights on the go.
For the best booking experience on the go, download Trip.com and search for cheap flights from Madrid to Panama City to access exclusive deals just for you.
Flight Info | Madrid to Panama City
Cheapest one-way flight price | $360 |
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Cheapest round-trip ticket price | $521 |
Off-season for travel | May |
Peak season for travel | December |
Flight distance | 8,177.05 km |
Average flight time | 10 hours 37 minutes |
Popular airline | avianca |
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